Sentences with phrase «from rosiglitazone»

Klotho is a secreted protein that can be measured in the serum of patients and this can help in determining which patients would benefit from rosiglitazone therapy and would be eligible for further studies.

Not exact matches

The researchers showed that the type 2 diabetes drug rosiglitazone, which increases insulin sensitivity, also protects neurons from ADDLs.

«Our compound clears lipids from the diabetic mouse liver, whereas rosiglitazone has the opposite effect,» said Saez.

Clinical trials of GlaxoSmithKline's diabetes drug Avandia (rosiglitazone) and Merck's anti-inflammatory Vioxx (rofecoxib) revealed an elevated cardiac risk from the drugs, but relevant findings were held back from regulators or never published.

Pini M, Rhodes DH, Castellanos KJ, Cabay RJ, Grady EF, Fantuzzi G. Rosiglitazone improves survival and hastens recovery from pancreatic inflammation in obese mice.

But women, already benefiting from metformin, improved heart metabolism further by adding rosiglitazone, with the desired effect of reducing the heart's dependence on fat metabolism.

The diabetes drug rosiglitazone has been under intense scrutiny since a 2007 study in the New England Journal of Medicine looked at more than 40 clinical trials and linked the drug's use with increased risk of heart attack and death from heart disease.

In the report, published in the December 2007 issue of Nature Medicine, researchers from the Salk Institute in La Jolla, California report that rosiglitazone (Avandia) has been shown to interfere with >> Read Article