Sentences with phrase «from small phase»

Early data from a small phase Ib / II study [23] of ipilimumab combined with T - VEC, which demonstrated that the combination offers much higher complete and overall response rates than have been seen with either agent alone, appear to confirm that there are beneficial synergies between these two therapeutic modalities.

In a few weeks, meeting participants learned, enough data may be available from small phase I trials of a vaccine jointly made by the U.S. National Institute of Allergy and Infectious Diseases and GlaxoSmithKline (GSK) that began in September to launch efficacy studies.

Not exact matches

In part, this will come from the consolidation of the tech sector and expansion of small firms still in a high - growth phase, comprising a large share of current serviced office users.

The superpatient person is like one who has a very serious illness, who has come through the most dangerous phase of the illness yet later unexpectedly dies from a sudden relapse of fever; the fever was finally the cause of death.15 Again, the superpatient person is like a soldier who has had a great victory in the field — the main battle is over; going into the city thinking the victory already secured, the negligent soldier is stupidly captured by a small, insignificant force within the gates.

Except in a few small islands in the Pacific, until 1914 the Christian communities which arose from missions from the West were small minorities, Christian enclaves in overwhelming non-Christian populations, dependent on continued infusions from Europe and America and regarded by the non-Christian neighbors as aliens, the religious phase of Western imperialism and colonialism.

Under the Montreal Protocol, Quarantine and Pre-Shipment and feedstock uses are not subject to phase - down, while non-Quarantine and Pre-Shipment uses (i.e. those uses that do not fall within the definition of Quarantine and Pre-Shipment or the definition of feedstock) have been phased out, apart from a small number of exempted critical uses.

Maybe in the newborn phase, you have a few small newborn ones and then you can get the one size ones that will fit from six or 10 pounds up to like 20 pounds.

As an only child from a small family I had never been exposed to the challenges of this phase of life.

He says small businesses are already «underwater» from high worker's compensation costs, taxes, and the new measure by the Cuomo administration to phase in a $ 15 dollar an hour minimum wage.

He says small businesses are already «underwater» from high worker's compensation costs, taxes, and the new measure by the Cuomo administration to phase in a $ 15 an hour minimum wage.

To encourage small businesses and farms to pass down their business from one generation to the next, the Senate proposed speeding up the full phase - in of estate tax reform first enacted in 2014.

They received $ 50,000 in phase I Small Business Innovation Research funding from the federal government, along with matching state funds that allowed Edwards — Hemmert moved on — to conduct early product research during his doctoral studies.

Anasys recently received a phase - 2 Small Business Innovation Research grant from DOE to couple atomic force microscopy and mass spectrometry in a commercial product.

The HYPO - RT - PC trial, a randomized multi-institutional phase III trial in Scandinavia, was designed to assess outcomes from highly accelerated extreme hypofractionation, which is delivered in smaller number of high doses — seven fractions of 6.1 Gy each in this study.

In 2011, Science's editors will be watching a smaller detector at the Large Hadron Collider called LHCb, which will study B mesons in great detail; new techniques that should lead to the discovery of many more genes contributing to adaptation; an ignited fusion burn at the National Ignition Facility; broadly neutralizing antibodies, which are capable of disabling a wide range of viral variants; the first plug - in hybrid electric cars whose batteries are charged from a wall socket go on the market; and the results of the first phase III trial of a malaria vaccine.

The Vestas Tower Crane, still in the prototype phase, is designed to attach to a cable lowered down from a small crane located inside the turbine tower's nacelle (the cover housing the wind turbine's generator and gearbox) and hoisted upward.

For instance, it was believed that the light from the smaller lasers would need to be precisely matched in color, phase, and other properties in order to produce the electron - accelerating motion within the plasma.

Small businesses working with DOE can also apply for a Phase 3 award to pursue commercial applications of the R&D, but those funds must come from non-SBIR or STTR sources.

The newly found titanium suboxide — called Magnéli phases — was once thought rare, found only sparingly on Earth in some meteorites, from a small area of rock formations in western Greenland, and occasionally in moon rocks.

In a small phase I and II clinical trial, Johns Hopkins researchers and colleagues elsewhere found that the high - fat, low - carbohydrate ketogenic diet was a safe and effective treatment option for the majority of adults experiencing a relatively rare, often fatal and always severe form of epilepsy marked by prolonged seizures that require medically induced comas to prevent them from further damaging the body and the brain.

Adding the monoclonal antibody drug trastuzumab — already used to treat certain breast cancers — to the chemotherapy regimen of women with a rare form of uterine cancer lengthens the amount of time their tumors are kept from growing, according to Johns Hopkins Medicine researchers conducting a small phase II trial of the regimen, testing its safety and value.

The dentate gyrus also generates theta waves, which are difficult to separate from the CA1 waves because they are considerably smaller in amplitude, but there is some evidence that dentate gyrus theta is usually about 90 degrees out of phase from CA1 theta.

Our group has 3 major goals: Develop novel therapeutic approaches based on centrosomal clustering To further develop our first prototype inhibitors of centrosomal clustering preclinically and to establish a robust and specific high throughput small molecule screen Discover key events in myeloma pathogenesis To investigate the pivotal transition from the pre-malignant, asymptomatic to malignant, symptomatic stages of plasma cell dyscrasias in order to understand the pathophysiology and thereby identify novel targets Translate small molecule therapeutics from bench to clinical trials To evaluate novel agents in the preclinical setting and to initiate early phase clinical trials in hematologic malignancies with focus on multiple myeloma

ViaCyte, Inc. (CA, USA) has received a Small Business Innovative Research Phase III award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK; MD, USA) to further the development of stem cell - derived functional human beta cells in vitro.

It would be nice to have a review of the «experiment's» (my word) two phases from the point of view of regional and global (I'm guessing small) climate effects.

Smaller, cheaper and easier to breed than mice, zebrafish in their juvenile phase can actually live in the tiny amount of liquid — ranging from tens of nanoliters to several milliliters — that fits in the wells of a standard 96 - well plate used to screen drug compounds.

During this phase, more oxygen needs to get to your muscles from the small blood vessels.

In sports it is only small period during the transition from an eccentric phase to the concentric phase.

By the end of the follicular phase, the luteinizing hormone surge results in ejection of the oocyte and transforms the remaining follicle into the corpus luteum; small and large luteal cells are formed from theca and granulosa cells, respectively.

This was later amended again to allow a phased rollout of late submission automatic penalties and saw employers with 50 or more employees being subject to these penalties as from 6th October 2014 and smaller employers enjoying a delay until 6th March 2015.

This research is limited in that it collected data solely from the teachers» point of view as expressed in focus groups and interviews in the first study phase, and the second phase is limited by its small sample of teachers.

Most notably, the IBO only looked at students who remained enrolled in schools while they phased out, not those who benefited from being able to attend new small schools.

The government will phase - in mandatory 1.9 per cent contributions from employers and workers over two years, starting with larger companies in 2017 before moving on to smaller operations like convenience stores and dry cleaners.

Zeniquin should not be used in cats younger than 12 months of age or dogs during their rapid growth phase, which can vary from 8 - 18 months based on the breed (small and medium breeds up to 8 months of age, large breeds up to 12 months of age, and giant breeds up to 18 months of age).

From the capital's small - town history to a booming tech city and all the phases in between, Austin Motel has stood privy to it all.

Set across five decks of a massive spaceship, robot opponents slash, shoot, launch missiles from their backs, fire screen sweeping lasers and create smaller enemies to attack, while the giant enemy bosses fight with everything they've got across multiple phases.

(PS diffusion of matter and energy (latent heat) during such phase changes requires compositional and temperature gradients — entropy must then be produced, so there is a departure from actually being adiabatic — a smaller departure if pressure is being changed less rapidly (so that diffusions occur across smaller gradients).

The starting point of this line is the average total quantity of allowances (phase 2 cap) to be issued by Member States for the 2008 - 12 period, adjusted to reflect the broadened scope of the system from 2013 as well as any small installations that Member States have chosen to exclude.

Jackson, R.C., G.M. McFarquhar, A. Fridlind, and R. Atlas, 2015: The dependence of cirrus gamma size distributions expressed as volumes in N0 - λ - μ phase space and bulk cloud properties on environmental conditions: Results from Small Ice Particles in Cirrus Experiment (SPARTICUS).

Interactions between externally - forced climate signals from sunspot peaks and the internally - generated Pacific Decadal and North Atlantic Oscillations «When the PDO is in phase with the 11 year sunspot cycle there are positive SLP anomalies in the Gulf of Alaska, nearly no anomalous zonal SLP gradient across the equatorial Pacific, and a mix of small positive and negative SST anomalies there.

The forcing was rather small before 1990, therefore the data starting from 1990 dominates the conclusions, and the total period since 1990 might be also suitable from the point of view of covering well enough different phases of natural variability.

This report found that phasing out the small remaining uses of ODSs, which are currently exempted from phase - outs, would hasten ozone recovery by about 11 years.

I understand that during that phase the atmosphere cools from the top down, leaving a small band of warm air only by the morning.

To point out just a couple of things: — oceans warming slower (or cooling slower) than lands on long - time trends is absolutely normal, because water is more difficult both to warm or to cool (I mean, we require both a bigger heat flow and more time); at the contrary, I see as a non-sense theory (made by some serrist, but don't know who) that oceans are storing up heat, and that suddenly they will release such heat as a positive feedback: or the water warms than no heat can be considered ad «stored» (we have no phase change inside oceans, so no latent heat) or oceans begin to release heat but in the same time they have to cool (because they are losing heat); so, I don't feel strange that in last years land temperatures for some series (NCDC and GISS) can be heating up while oceans are slightly cooling, but I feel strange that they are heating up so much to reverse global trend from slightly negative / stable to slightly positive; but, in the end, all this is not an evidence that lands» warming is led by UHI (but, this effect, I would not exclude it from having a small part in temperature trends for some regional area, but just small); both because, as writtend, it is normal to have waters warming slower than lands, and because lands» temperatures are often measured in a not so precise way (despite they continue to give us a global uncertainity in TT values which is barely the instrumental's one)-- but, to point out, HadCRU and MSU of last years (I mean always 2002 - 2006) follow much better waters» temperatures trend; — metropolis and larger cities temperature trends actually show an increase in UHI effect, but I think the sites are few, and the covered area is very small worldwide, so the global effect is very poor (but it still can be sensible for regional effects); but I would not run out a small warming trend for airport measurements due mainly to three things: increasing jet planes traffic, enlarging airports (then more buildings and more asphalt — if you follow motor sports, or simply live in a town / city, you will know how easy they get very warmer than air during day, and how much it can slow night - time cooling) and overall having airports nearer to cities (if not becoming an area inside the city after some decade of hurban growth, e.g. Milan - Linate); — I found no point about UHI in towns and villages; you will tell me they are not large cities; but, in comparison with 20-40-60 years ago when they were «countryside», many small towns and villages have become part of larger hurban areas (at least in Europe and Asia) so examining just larger cities would not be enough in my opinion to get a full view of UHI effect (still remembering that it has a small global effect: we can say many matters are due to UHI instead of GW, maybe even that a small part of measured GW is due to UHI, and that GW measurements are not so precise to make us able to make good analisyses and predictions, but not that GW is due to UHI).

It would be nice to have a review of the «experiment's» (my word) two phases from the point of view of regional and global (I'm guessing small) climate effects.

He has many years of experience representing a variety of clients ranging from Fortune 500 companies to small business owners in all phases of litigation including complex commercial cases, corporations, contracts, deceptive trade practices, mass toxic tort cases, premises liability, products liability, and general civil litigation.

He has many years of experience representing a variety of clients ranging from Fortune 500 companies to small business owners in all phases of litigation including complex commercial...

Ultimately, it seems like a fairly iterative update which consists mostly of tweaks — wider aperture, OIS, more advanced phase detection, smaller pixels — but if those tweaks come together to substantially improve what was already a stellar camera experience from the previous generation, I can certainly see the device leading the industry in this respect.

Major strengths include the ability to successfully and profitably manage numerous small, medium and multi-million dollar turnkey concurrent projects through all project phases from conception through completion within targeted cost, sched...

The second phase is eliciting from the child criticisms of you, however small, that are then inflamed and distorted by the response these elicited criticisms receive from the narcissistic / (borderline) parent.