Sentences with phrase «from the bone marrow transplant»

Writing in Journal of Immunology, lead author and BSI member, Professor Graham Anderson explains, «Post-transplantation, T - cell progenitors derived from the bone marrow transplant can struggle to enter the thymus, as if the doorway to the thymus is closed.

Further information is available from our Bone Marrow Transplant Unit under the direction of Dr. Steven Suter.

Not exact matches

Etkin and Schultz did not know each other at the time, but a mutual friend from the Hamptons heard that Susan was going to Seattle for a bone marrow transplant in early 1997.

Enlivex is developing a treatment for Graft - versus - Host disease (GvHD) resulting from bone - marrow transplants.

At the age of 19, I was diagnosed with leukemia and treated with chemo and a bone marrow transplant from my sister.

A drug used to stop immune cells from gobbling up transplanted organs and bone marrow has been caught boosting the immune response to a virus in mice and monkeys.

In the early 2000s, Johns Hopkins scientists Leo Luznik and Ephraim Fuchs found that giving patients high doses of cyclophosphamide — a drug derived from nitrogen mustard and used to treat blood cancers — three days after bone marrow transplant successfully thwarts acute and chronic GVHD.

The Boston patients, in contrast, are free of the virus thanks to a combination of a bone marrow transplant plus continuing antiretroviral drugs to stop newly donated immune cells from being infected.

They both had standard chemotherapy to kill their native blood cells before undergoing a bone - marrow transplant from a donor to repopulate their blood.

St. Jude Children's Research Hospital leads study showing that a drug withdrawn from the market in 2010 may enhance the effectiveness of bone marrow transplants for select pediatric leukemia patients

Two men known only as the «Boston patients» have both stopped taking their anti-HIV medications following transplants of bone - marrow stem cells that appear to have banished the virus from their bodies.

Researchers at Dana - Farber / Boston Children's Cancer and Blood Disorders Center report promising outcomes from a clinical trial with patients with a rare form of bone marrow failure who received a hematopoietic stem cell transplant (HSCT) after pre-treatment with immunosuppressive drugs only.

«When we transplanted our labeled blood stem cells from the bone marrow into other mice, only a few stem cells were active in the recipients, and many stem cells were lost,» Rodewald explains.

In recent studies of cancer patients who received a bone marrow transplant, genes from the marrow's white blood cells were found in the patient's tumor cells.

These so - called hematopoietic stem cells (from Greek meaning «to make blood») have been reliably used over the past 40 years to seed bone marrow transplants in the treatment of some cancers and immune disorders.

We also know that patients who receive bone marrow transplants from less compatible donors have a lower risk of developing new cancers.

HSCs can be harvested from a suitable donor and then transplanted into a patient, where, after establishing themselves in the bone marrow, they can generate healthy blood cells.

Now, in a study recently published in the journal PLOS ONE, a team of scientists from VCU Massey Cancer Center have shown a genetic relationship between the reactivation of hCMV and the onset of graft - versus - host disease (GVHD), a potentially deadly condition in which the immune system attacks healthy tissue following a bone marrow or stem cell transplant.

What's interesting is that when you do a bone marrow transplant for cancer, some of those with autoimmune disease go into remission, as if the immune system has been eliminated and allowed to rebuild from scratch.

To treat hereditary blood diseases, doctors could take a sample of bone marrow cells from a patient, correct the faulty gene, and then grow healthy cells in the bioreactor and transplant them back into the patient.

Then they infused him with a bone marrow transplant from his brother.

More recently, physicians have learned how to harvest blood - forming stem cells from a donor's blood and transplant them into a patient, sidestepping the need for an operating room and a needle stick into the pelvis to extract bone marrow.

His Hutch team found that leukemia patients who received bone marrow transplants from an identical twin had far higher relapse rates than people who used a closely matched, but not identical, sibling.

GVHD affects up to half of the more than 30,000 people worldwide each year who receive an immune system transplanted from a donor, as either bone marrow or peripheral blood stem cells.

They then carried out bone marrow transplants to replace the immune system with one from mice that showed either high or low levels of interleukin - 6 levels in response to stress.

This technology has been developed from a skin explant model for predicting a potentially serious complication of bone marrow transplantation, «graft versus host» disease — a common complication following the transplant.

Scientists in Germany have developed a new approach that may prevent leukemia and lymphoma patients from developing graft - versus - host disease (GvHD) after therapeutic bone marrow transplants.

Using stem cells harvested from human bone marrow, researchers transplanted cells into mice modeling ALS and already showing disease symptoms.

- host, because it may also help prevent the leukemia from returning,» says Reddy, who is also co-director of the hematologic malignancies and bone marrow transplant program at the U-M Comprehensive Cancer Center.

The study enrolled 61 older adults from the University of Michigan and Washington University in St. Louis who were undergoing a reduced - intensity bone marrow transplant with cells donated from a relative.

«This condition is one of the main reasons that many bone marrow transplant patients endure long hospital stays after their diseases are cured,» said Kean, who wears a bracelet around her badge from a pediatric patient cured of leukemia one year ago, but is still in the hospital due to complications from GVHD.

A new class of drugs reduced the risk of patients contracting a serious and often deadly side effect of lifesaving bone marrow transplant treatments, according to a study from researchers at the University of Michigan Comprehensive Cancer Center.

In patients with GVHD, newly transplanted T cells from the bone marrow graft attack the transplant recipient's body.

To test whether adipose tissue F4 / 80 + cells shared a common bone marrow origin with other tissue macrophage populations, we transplanted bone marrow from C57BL / 6J mice expressing the CD45.1 leukocyte marker into 6 - week - old lethally irradiated C57BL / 6J mice expressing the CD45.2 leukocyte marker.

Recently, an HIV infected patient with acute myelogenous leukemia received a bone marrow transplant from a ccr5Δ32 homozygous donor [6].

The concept was first tested inadvertently in Germany in 2006, when a person with leukaemia who was also HIV positive received a bone marrow transplant that happened to come from someone whose blood cells couldn't make CCR5 proteins.

For some, bone marrow transplant from a matched sibling donor or a matched, unrelated donor may be favored when remission is obtained.

Dr. Goodman is also involved in collaborative efforts with the San Antonio Bone Marrow Transplant Center to study the outcome of allogeneic bone marrow transplants following a relapse from autologous bone marrow transplaBone Marrow Transplant Center to study the outcome of allogeneic bone marrow transplants following a relapse from autologous bone marrow transpMarrow Transplant Center to study the outcome of allogeneic bone marrow transplants following a relapse from autologous bone marrow transplabone marrow transplants following a relapse from autologous bone marrow transpmarrow transplants following a relapse from autologous bone marrow transplabone marrow transpmarrow transplants.

For example, a bone - marrow transplant is accomplished by injecting stem cells from a donor into the bloodstream of the patient.

Additional trials were excluded from consideration if their only relationship to stem cells involved now - conventional unmanipulated bone marrow or cord blood transplants.

In the future, outpatient blood and bone marrow stem cell transplantation will be offered to a broader group of patients with other blood disorders and for allogeneic transplants (transplant from non-twin donor stem cells).

The South Florida Bone Marrow / Stem Cell Transplant Institute is now running a new clinical trial protocol (08001 - BMSCTI) for investigating a novel cancer therapy using transfusions of white blood cells from healthy donors.

A US - Brazilian project with 23 patients found most were able to produce their own insulin after a transplant of stem cells from their own bone marrow.

We welcome referrals from other doctors whose patients need bone marrow transplants.

This is why transplants of HSCs (from bone marrow) are also used to treat cancers of the hematopoietic (blood) system, such as leukemia or lymphoma.

To study blood development, researchers typically purify blood stem cells from the bone marrow of mice and transplant them into mice exposed to radiation, thus creating a tractable experimental system.

On day 0, recipient mice were transplanted with 5 × 106 T cell — depleted bone marrow (TCD - BM) cells and 1 × 106 spleen T cells from B6 donors.

In the late 1940s, University of Chicago researcher Dr. Leon Jacobson discovered that he could save a mouse, whose bone marrow and spleen had been destroyed with radiation, by transplanting healthy spleen tissue from another mouse.

Patients receive one of two types of stem cell - based transplants: autologous, in which a patient donates and receives back his / her own stem cells; or allogeneic, in which bone marrow - derived stem cells come from a related or unrelated donor whose human leukocyte antigens (HLA) are genetically matched with those of a patient.

The condition that results when the immune cells of a transplant (usually of bone marrow) from a donor attack the tissues of the person receiving the transplant.