The data set, one of the largest of its kind, includes primary data and associated metadata from nearly 530,000 immune cells
from umbilical cord blood of newborns and bone marrow of adults.
Not exact matches
Stem cells can be obtained licitly, without loss
of human life — for example,
from an adult organism or
from the
blood of the
umbilical cord at the time
of birth.
The bones
of the middle ear and the nerve endings
from the brain are developing so that your baby will hear sounds such as your heartbeat and
blood moving through the
umbilical cord.
The bones
of the inner ear and the nerve endings
from the brain have developed enough so that your little one will hear sounds such as your heartbeat, your stomach growling and
blood moving through the
umbilical cord.
From ads in parenting magazines, direct mailings, and flyers in their obstetrician's office, expecting parents are repeatedly told
of their «once - in - a-lifetime chance» to save their baby's
umbilical cord blood for possible use later to save his life.
Blood from the mother goes through the placenta into the attached umbilical cord and into the blood of the growing f
Blood from the mother goes through the placenta into the attached
umbilical cord and into the
blood of the growing f
blood of the growing fetus.
In one
of the most recent studies to document the extraordinary exposure and accumulation
of pollutants and toxins in children today, the
umbilical cord blood of babies
from around America was tested for toxins at the time
of their births.
Instead
of tossing it aside, some doctors, scientists and parents are choosing to bank this fetal
blood — harvesting it
from the baby's
umbilical cord and placenta, freezing it and storing it away for later.
But the factor that may make the discovery very significant is that
umbilical cord blood can be saved, stored and multiplied without any
of the ethical dilemmas facing embryonic stem cell use, which are derived
from human fetuses.
Investigators found that the presence
of cotinine, which results
from the breakdown
of nicotine in the body, in the
umbilical cord blood of newborns increased their risk
of developing asthma by age 7 years.
The amount
of blood that can be milked
from an
umbilical cord is not huge.
The stem cells, derived
from human
umbilical cord -
blood and coaxed into an embryonic - like state, were grown without the conventional use
of viruses, which can mutate genes and initiate cancers, according to the scientists.
Stem cells
from umbilical cord blood are highly prized for their ability to change into the cells
of other tissues.
To assess risk, Thomas Adamkiewicz, codirector
of the Hemoglobinopathy / Genomics Training Program at Morehouse School
of Medicine in Atlanta, surveyed four medical centers and found that seven children with sickle - cell disease had been treated with
umbilical cord blood from unrelated donors.
Using stem cells
from umbilical cord blood, researchers are growing clusters
of real liver cells in the lab.
In the new study, scientists compared weight gain for 325 expectant mothers
from Avilés, Spain, with the levels
of 35 chemicals in their babies»
umbilical cord blood.
The technology to grow NK cells
from umbilical cord blood was developed by Nina Shah, M.D., assistant professor and Elizabeth J. Shpall, M.D., professor in the department
of Stem Cell Transplantation and Cellular Therapy at The University
of Texas MD Anderson Cancer Center.
«Our group pioneered the development
of cell culture technology for harvesting large numbers
of stem cells
from human bone marrow and human
umbilical cord blood,» Dr. Yeh said, noting that stem cells
from these two sources are abundant and can be guided into different types
of cells using tissue engineering.
In general, founder cells are easy to acquire
from a donor and come in one
of four types: fibroblasts, keratinocytes, peripheral and
umbilical cord blood, and dental pulp cells.
So beginning in 2000, the University
of Minnesota began a new approach: using stem cells
from two
umbilical cord blood sources, which increased the chances
of engraftment in adults to 90 percent.
While still attached to its mother via the
umbilical cord, the baby received a temporary pacemaker, which stabilized its dangerously low and irregular heart rate and ensured enough
blood flow
from the heart to the rest
of its body for delivery.
Won Soon Park, MD, PhD, and colleagues
from Samsung Medical Center and Biomedical Research Institute, Seoul, Republic
of Korea, conducted a phase I, single - center trial
of intratracheal transplantation
of human
umbilical cord blood - derived mesenchymal stem cells to nine very preterm infants (24 - 26 weeks gestational age) who were at high risk
of developing BPD.
Blood from the
umbilical cord «is one
of the best measures
of contaminants being transferred
from mother to fetus,» said Sharon Sagiv, lead author
of the study and an epidemiologist who now works at Boston University.
Additional data *
of immune cells
from umbilical cord blood and adult bone marrow was provided by the Broad Institute
of MIT and Harvard.
At that key point, Takebe added two more types
of cell known to help to recreate organ - like function in animals: endothelial cells, which line
blood vessels, taken
from an
umbilical cord; and mesenchymal cells, which can differentiate into bone, cartilage or fat, taken
from bone marrow.
An innovative experimental treatment for boosting the effectiveness
of stem - cell transplants with
umbilical cord blood has a favorable safety profile in long - term animal studies, report scientists
from Dana - Farber Cancer Institute, Beth Israel Deaconess Medical Center (BIDMC), and Children's Hospital Boston (CHB).
In late 2015, the company also launched its MagCloudz streptavidin cell - separation kit and partnered with the University
of Massachusetts Medical School in research toward the enrichment and purification
of CD3 + T cells
from human
umbilical cord blood.
Allogeneic cell transplantation enables the use
of «younger» cells,
from fetal origins (e.g.,
umbilical cord blood, placenta) or healthy donors, which are considered to be effective due to higher regenerative potential and plasticity.
DBA
Cord Blood Registry (CBR) are collaborating to customize the creation of high - quality stem cell lines from umbilical cord blood tissu
Cord Blood Registry (CBR) are collaborating to customize the creation of high - quality stem cell lines from umbilical cord blood tiss
Blood Registry (CBR) are collaborating to customize the creation
of high - quality stem cell lines
from umbilical cord blood tissu
cord blood tiss
blood tissue...
Unlike embryonic stem cells
from earlier in development, fetal stem cells
from umbilical cord blood are multipotent - they can develop into a limited number
of cell types.
One type
of stem cell transplant, autologous hematopoietic stem cell transplantation, uses stems cells
from your own bone marrow, or
from external
umbilical cord blood.
In a study
of umbilical cord blood from New York City children, researchers found a change in a gene called ACSL3 that is associated with prenatal exposure to chemical pollutants called polycyclic aromatic hydrocarbons (PAHs), which are byproducts
of incomplete combustion
from carbon - containing fuels, resulting in high levels in heavy - traffic areas.