Sentences with phrase «from zebrafish»

Rawls, J. F., Mahowald, M. A., Ley, R. E. & Gordon, J. I. Reciprocal gut microbiota transplants from zebrafish and mice to germ - free recipients reveal host habitat selection.

To learn from zebrafish how to enable the adult brains to better cope with neurodegenerative disease and regenerate

These feeder cells, derived from zebrafish testicular cancer cell lines, promote the growth of spermatagonia and stimulate them to mature into functional sperm,» said Dr. Sakai, the study's senior author and a reproductive biologist.

In addition, the significant number (> 1000) novel models that came from RNA - Seq that were absent from the zebrafish cDNAs suggests that the deep sequencing offered by RNA - Seq can be used to expand the gene annotation of even well - studied model organisms.

Western blotting of phospho - Smad1 / 5/8 from zebrafish embryo extracts was previously described (35).

As further evidence of BMP signaling activation, proteins isolated from zebrafish embryos were examined by immunoblotting for phosphorylated Smad1 / 5.

«New clues to treat Alagille Syndrome from zebrafish: How Jagged genes establish liver duct cell lineage.»

The study, led by Yadong Wang, the William Kepler Whiteford Professor in Bioengineering in the Swanson School of Engineering and the principal investigator of the Biomaterials Foundry at Pitt, found that a single administration of extracellular matrices (ECM) from zebrafish hearts restored the function of the heart and regenerated adult mouse heart tissues after acute myocardial infarction.

The researchers tested the effectiveness of ECM from normal zebrafish and from zebrafish with damaged hearts, in which the ECM had already begun the healing process.

They found that while both types of ECM were effective in repairing damage to the mice hearts, the ECM obtained from the zebrafish hearts that were healing were even more potent in restoring heart function in the mice.

«Regenerative potential of cells in mouse retina: Researchers use a clue from zebrafish to discover the cues that reprogram Müller glia into retinal neurons.»

The next steps for the research group are to use what they have learned from this zebrafish model of gut inflammation to design better probiotics to treat intestinal inflammation.

Not exact matches

Predatory bacteria can efficiently eat other gram - negative bacteria, munch through biofilms and even save zebrafish from the jaws of an infectious death.

The design differs from that of a conventional commercial microscope: Keller placed the laser and objective lens at right angles to each other atop a table; then he embedded zebrafish embryos in agarose in a sample tube between the two.

The study found that zebrafish that failed to inherit specific genetic instructions from mom developed fatal defects earlier in development, even if the fish could make their own version of the gene.

Although reindeer noses aren't typically red, or infused with enough light to guide a sleigh, Farber says other earthly creatures are that color and glow through bioluminescence or fluorescence — everything from jelly fish to sea anemones to the zebrafish he studies.

The zebrafish is a tropical, freshwater fish that comes from Asia.

Taking the example of cocaine, researchers at Eawag, together with colleagues at Zurich University, have now shown that the uptake and distribution patterns and the effects of the drug in zebrafish differ in many ways from those in mammals.

Often, those smaller animals express the genetic abnormality very differently from humans, says clinical scientist and pediatric neurologist James Dowling at the University of Michigan, Ann Arbor, who studies the myopathies and their genetic causes in both children and zebrafish.

Zebrafish in which ctgfa was disabled had glial cells that often failed to extend into the lesions, and the fish were unable to recover from spinal injury.

Removing a single gene from the brains of mice and zebrafish causes these animals to become more anxious than normal.

Similar to zebrafish, mice in which Lef1 had been removed from the hypothalamus showed signs of anxiety, including being smaller and a reluctance to explore.

«Although zebrafish look quite different from humans, they share an astonishing 70 percent of their genetic material with humans, including genes important for the formation of new heart muscle,» Yin said.

Which leaves only those poor insomniac zebrafish, for whom I bear tidings that should have church bells ringing from one end of Zebrafish Land to the other immediately upon their receipt: Apparently, fish don't just get zebrafish, for whom I bear tidings that should have church bells ringing from one end of Zebrafish Land to the other immediately upon their receipt: Apparently, fish don't just get Zebrafish Land to the other immediately upon their receipt: Apparently, fish don't just get insomnia.

Instead of mice, it produces fluorescent zebrafish, which are easier for the undergraduate - staffed lab to handle, in part because they go from fertilization to free - swimming fish in a matter of days.

Mark T. Keating and his colleagues at Harvard Medical School wounded the hearts of adult zebrafishes by surgically removing 20 percent of the muscle from the lower chamber.

The results from McCammon's initial screen with zebrafish indicate that two genes in the 16p11.2 region could be key for brain development: fam57ba and doc2a.

The researchers believed that by triggering the microglia to transition from phase 1 to phase 2 more quickly by using the drug, they could improve the zebrafishes» regenerative capabilities.

Based on analyses of scales from highly relevant species for aquaculture such as common carp (Cyprinus carpio), gilthead sea bream (Sparus aurata), sea bass (Dicentrarchus labrax), Mozambique tilapia (Oreochromis mossambicus), Atlantic salmon (Salmo salar), rainbow trout (Oncorhynchus mykiss) and pike perch (Stizostedion lucioperca) as well as from fish commonly used in experimental studies such as zebrafish (Danio rerio), it was found that glucocorticoids, especially cortisol, incorporate in fish scales over time.

These DNA elements have epigenetic functions that are similar in zebrafish and human melanoma and could potentially be targeted with drugs to stop a mole from becoming cancerous.

Finally, they demonstrated that zebrafish OPCs differentiate into mature oligodendrocytes when cultured together with human motor neurons, differentiated from induced pluripotent stem cells.

When zebrafish with the green fluorescing endothelial gene matured, the researchers observed green FGPs on the surface of the fish's brains — confirming that these cells arose from endothelial tissue.

National Institutes of Health researchers studying zebrafish have determined that a population of cells that protect the brain against diseases and harmful substances are not immune cells, as had previously been thought, but instead likely arise from the lining of the circulatory system.

In addition to fruit flies, they successfully used the program to analyze images of zebrafish and mice, as well as data collected from a commercial light sheet microscope and a commercial confocal microscope.

When the scientists prevented the genes from working in zebrafish, they failed to develop fingerlike projections called fin rays — the fishes» «hands.»

In a paper published in the journal PLOS ONE, MDI Biological Laboratory scientists Benjamin L. King, Ph.D., and Voot P. Yin, Ph.D., identified these common genetic regulators in three regenerative species: the zebrafish, a common aquarium fish originally from India; the axolotl, a salamander native to the lakes of Mexico; and the bichir, a ray - finned fish from Africa.

Because these genes have the same function in zebrafish, humans, and other tetrapods, it should help researchers further understand how our ancestors left the water and evolved limbs from fins.

In the current study, the researchers showed that FGPs are present on the surface of the zebrafish brain and that these blood vessel - associated FGPs do not arise from the immune system, as had been previously thought, but from endothelial cells themselves.

Tobin also uses zebrafish to study bacteria closely related to those that cause tuberculosis, and findings from this model have been applied to understanding human disease.

Ruvkun's work showed that a microRNA called let - 7 regulates maturation from the larval stage to adulthood — and that it operates in many creatures, from fruit flies to zebrafish to mollusks.

New research from a team including Carnegie's Daniel Gorelick and Marnie Halpern on the effects of these chemicals on zebrafish shows that embryonic heart valves could be particularly in danger.

Zebrafish (Danio rerio) embryos illustrating the function of the transporter protein Abcb4 acting as effective chemical defense by keeping out chemical compounds from the embryos.

His group also worked frantically without an electric pump to change the water in their 125 40 - liter tanks of transgenic zebrafish, which otherwise would have died from lack of oxygen.

«The scales of sharks and skates are very different from the scales of zebrafish [and other] types of bony fish,» he said.

The study, published in Nature Communications, examined the changes that occur in cancer cells as they break away from tumours in cell cultures, zebrafish and mice.

Sometimes referred to as the stem cells of the zebrafish eye, Müller glia are the cells from which all other types of retinal cells are regenerated in the fish.

Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim, together with U.S. colleagues, have now observed in the embryo of the zebrafish that muscle cells migrate from the undamaged atrium into the ventricle and thus significantly contribute to regeneration.

The researchers placed the robot in a shared tank with shoals of live zebrafish, aiming to determine if the fish would perceive the robot as a predator, and whether visual cues from the robot could be used to modulate the fishes» social behavior and activity.

The resulting zebrafish grew an extra tail — and only a tail — that extended from its trunk.

By observing whole - brain activity in live zebrafish, researchers from the RIKEN Brain Science Institute have visualized for the first time how information stored as long - term memory in the cerebral cortex is processed to guide behavioral choices.