In July, a 33 - year - old woman in Edinburgh became the first in Britain to give birth after having
frozen ovarian tissue returned to her body.
Doctors have performed similar operations before and about 60 women have had their fertility restored with
frozen ovarian tissue since 2001.
If the approach works in women it could be used to boost fertility or help those who
froze ovarian tissue prior to chemotherapy.
Ovarian tissue freezing, an outpatient procedure which removes and
freezes ovarian tissue for later use, can deliver these outcomes but has been considered experimental until now.
Not exact matches
Helen Picton, who oversaw the tissue -
freezing at Leeds University, told the BBC that in Europe alone, several thousand girls and young women have had
ovarian tissue
frozen and stored.
«Is «
ovarian tissue
freezing» superior to egg
freezing?.»
309
ovarian tissue
freezing procedures resulted in 84 births and 8 pregnancies that lasted beyond the first trimester.
Using
frozen embryos lowered the rate of
ovarian hyperstimulation syndrome compared to using fresh embryos from 7.1 to 1.3 percent.
Frozen embryo transfer allows a woman's ovary to recover from
ovarian stimulation during in vitro fertilization and also gives time for her exposed endometrial lining to shed.
This «
freeze - all» approach, initially developed as a strategy for minimising risk of
ovarian hysperstimulation syndrome (OHSS) in high risk patients, also addresses concerns that some have raised that the drugs used for
ovarian stimulation during IVF may have a negative impact on the uterine receptivity of some patients.
Recently Kutluk Oktay, the chief of reproductive endocrinology and infertility at New York Methodist Hospital in Brooklyn, has been experimenting with
freezing and transplanting swatches of
ovarian tissue.
While individual, already - developed eggs die easily when
frozen, immature follicle eggs embedded in the
ovarian tissue fare a lot better.
The need for better access to fertility preservation has become more pressing in recent years for two reasons: first, the improved rates of survival in young women and girls diagnosed with cancer; and second, improvements in the techniques of
freezing eggs and
ovarian tissue to restore fertility.
«Oocyte and embryo
freezing are regarded as established,» he said, «but
ovarian tissue cryopreservation is considered experimental, although it is the only option for prepubertal girls.»
«This study reinforces our previous research by noting that the elective
freezing of embryos is safer for all IVF patients (ovulatory and anovulatory) by reducing the risk of
ovarian hyperstimulation syndrome,» Legro said.
Previous research from the team showed that using
frozen embryos resulted in more live births among women with polycystic
ovarian syndrome — women who do not ovulate normally — but the researchers said not as much was known about using fresh versus
frozen embryos in women who do ovulate normally.
The researchers also found that using
frozen embryos resulted in a lower risk of the woman developing
ovarian hyperstimulation syndrome, a condition that sometimes affects women undergoing fertility treatment.
Reality star Diem Brown of MTV's Real World / Road Rules Challenge was recently diagnosed with
ovarian cancer for a second time, and she's now going through fertility treatments in the hopes of
freezing her eggs before her second ovary is removed, she shares on People.com.
She is an expert in ovulation induction, in vitro fertilization, egg
freezing and egg donation, as well as the management of recurrent pregnancy loss, endometriosis, and polycystic
ovarian syndrome.
The embryos have been
frozen and I'm cleaning out my body from the mild
ovarian stimulation drugs and optimizing my health before I do the embryo transfer.