Scientists at the Max Planck Institute of Neurobiology in Martinsried have now come one crucial step closer to this «holy grail of motion vision»: They identified the cells that represent these so - called «elementary motion detectors» in
the fruit fly brain.
«Mapping behavior in
the fruit fly brain.»
New research by neuroscientists at Cold Spring Harbor Laboratory (CSHL), published in The Journal of Neuroscience, reveals a set of cells in
the fruit fly brain that respond specifically to food odors.
Circled green spots are the cell bodies of two dNPF neurons, one in each hemisphere of
the fruit fly brain.
Using a combination of molecular biology, neurobiology and behavioral tests, the researchers now show that loss of ATF1 changes the response of
the fruit fly brain to a whiff of yeast.
Their end goal is to identify specific populations of neurons in
the fruit fly brain that are necessary for emotion primitives — and whether these functions are conserved in higher organisms, such as mice or even humans.
The program has already found some new features of
the fruit fly brain, said study coauthor Hanchuan Peng of the Howard Hughes Medical Institute's Janelia Farm Research Campus in Ashburn, Va. «We can see very beautiful and very complicated patterns,» said Peng, who presented the results April 9 at the 51st Annual Drosophila Research Conference.
«New light sensing molecule discovered in
the fruit fly brain: The discovery could help inform future research into degenerative retinal disorders.»
Davis now plans to investigate the precise function of integrins in
the fruit fly brain.
Gaiti Hasan's team from NCBS has now uncovered how this happens — the researchers have discovered an integrative circuit of nerve cells in
fruit fly brains that allows them to ignore the lack of proteins in their food to enter the pupal stage.
«
Fruit fly brains shed light on why we get tired when we stay up too late.»
The study uses imaging technology and electrophysiology to understand what happens between neurons at synapses to make sense of how
fruit fly brains process odors.
Not exact matches
These cells appear to be absent in the
brains of female
fruit flies.
According to the latest studies from the
fly laboratory of California Institute of Technology (Caltech) biologist David Anderson, male Drosophilae, commonly known as
fruit flies, fight more than their female counterparts because they have special cells in their
brains that promote fighting.
So they engineered
fruit flies» genes to enhance or repress the activity of Rac in their
brains and taught them to associate a smell with an electric shock.
Bingwei Lu, a neuroscientist at Stanford University in California, has shown that a microRNA sequence which suppresses certain genes is linked to the death of
brain cells in
fruit flies.
Fruit flies with the mutant form of LRRK2 also had a disrupted microRNA pathway associated with the gene, and accumulated toxic proteins that killed motor - coordinating neurons in the
brain.
Many studies have linked more sleep to better memory, but new research in
fruit flies demonstrates that extra sleep helps the
brain overcome catastrophic neurological defects that otherwise would block memory formation, report scientists at Washington University School of Medicine in St. Louis.
Then, Lorin Milescu's students used live - imaging techniques and software developed in their lab to demonstrate that the Gr28bD protein can, through temperature differences, modulate the
brain activity of
fruit flies.
Shaw works with
fruit flies to explore the
brain mechanisms that control sleep, which he and others have shown to be similar to those seen in people.
RED - LIGHT DISTRICT Levels of a
brain reward compound increased in male
fruit flies genetically engineered to ejaculate when exposed to red light when the insects were bathed in the rosy hue.
However, testing the validity of data analysis algorithms is difficult since it is still unclear how even relatively simple neural systems like the
brain of a
fruit fly work.
Left: A
fruit fly showing location of
brain pacemaker cells that express rhodopsin 7.
New research shows that a seventh rhodopsin, Rh7, is expressed in the
brain of
fruit flies where it regulates the
fly's day - night activity cycles.
Feeding the
fruit flies spermidin significantly reduced the amount of protein aggregates in their
brains, and their memories improved to juvenile levels.
Newly hatched
fruit flies deprived of sleep end up with
brain and behavior problems later in life, scientists report in the April 18 Science.
With increasing age, the proteins accumulate in the
brains of
fruit flies, mice, and humans.
Slumber is known to improve recall in creatures from
fruit flies to humans, and the reigning theory among neuroscientists has been that the waves of
brain activity during deep sleep reactivate neurons that were triggered during the day, strengthening neuronal connections and cementing them into solid memories.
The switch in the
brain that sends us off to sleep has been identified by researchers at Oxford University's Centre for Neural Circuits and Behaviour in a study in
fruit flies.
In the
fruit fly, the ability to distinguish smells lies in a region of the
brain called the mushroom body (MB).
The surprising details of this process, observed in the
brains of
fruit flies, could shed light on how the human
brain develops — and what happens when problems arise.
A protein that can switch shapes and accumulate inside
brain cells helps
fruit flies form and retrieve memories, a new study finds.
He has measured
brain waves in sleeping
fruit flies, identified genes that are active in humans during sleep, and demonstrated that sleep enhances learning and memory.
To understand the development of the human
brain, the researchers looked to a much simpler animal, the
fruit fly, in which they could control and observe cells more easily.
Synaptic connections (shown from different angles, top and bottom) developed during a
fruit fly's waking hours (left) were pared down after sleep (right), confirming that the
brain does some housecleaning during slumber to keep only the most useful connections.
Using the
fruit fly Drosophila melanogaster as a model, the team led by Prof. Dr. Christoph Schuster and Prof. Dr. Hilmar Bading investigates how the
brain learns.
Historically, animal models — from
fruit flies to mice — have been the go - to technique to study the biological consequences of aging, especially in tissues that can't be easily sampled from living humans, like the
brain.
A scent's location on the map also predicts the
brain activity caused by getting a whiff: previous research in a variety of animals such as
fruit flies, honeybees, mice, rats and tadpoles showed that neighboring odors cause similar patterns of neuron activity.
In a 2012 paper in Neuron, based on meetings organized by the Oxnard, California - based Kavli Foundation, Yuste and colleagues laid out a plan to progress gradually from mapping the
brain activity of simple model organisms such as the
fruit fly to charting the
brains of creatures that contain roughly 1 million neurons, such as the Etruscan shrew.
The researchers studied the
fruit fly Drosophila melanogaster, a model animal for learning about the
brain and its communication channels.
Researchers led by investigators Jerry Workman, Ph.D. and Susan Abmayr, Ph.D. at the Stowers Institute for Medical Research found that
fruit flies that lack Ataxin - 7 experience neurodegeneration in the
brain and the eye — paralleling the effects of the human disease.
In both mouse and
fruit fly embryos, Detlev Arendt, an evolutionary biologist at the European Molecular Biology Laboratory in Heidelberg, Germany, has found that cells involved in forming the
brain and nerve cord divide into three columns of cells.
Knocking down the expression of either the
fruit fly version of the FOXD1 gene or the
fruit fly version of ALDH1A3 blocks the formation of
brain tumors in a
brain cancer model of the
fruit fly species Drosophila melanogaster, the researchers found.
Gallio and his team wanted to study the
brain activity of a
fruit fly while it performed a complex behavior, but this is not easily achieved under a microscope.
Brain scientist Professor Thomas Nowotny was surprised to find that the «nose» of
fruit flies can identify odours from illicit drugs and explosive substances almost as accurately as wine odour, which the insects are naturally attracted to because it smells like their favourite food, fermenting
fruit.
In earlier research involving
fruit flies, Professor Verstreken had already demonstrated that a protein known as «Skywalker» plays a crucial role in maintaining communication between
brain cells.
What do our heads and
brains have in common with the anatomy of a
fruit fly?
Alessia Soldano and Bassem Hassan (VIB / KU Leuven) were the first to unravel the function of APPL — the
fruit -
fly version of APP — in the
brain of healthy
fruit flies.
Now a team of researchers has used computer - vision and machine - learning techniques in
fruit flies to create behavior anatomy maps that will help us understand how specific
brain circuits generate Drosophila aggression, wing extension, or grooming.
Boyden's team has also worked on the
brains of
fruit flies and zebrafish, while a collaborating group is applying expansion microscopy to human
brains.