Sentences with phrase «fruit fly genes»

UNE researchers have discovered a dozen or so fruit fly genes to target for the treatment of chronic pain.

Fruit fly genes overlap with humans by about 70 percent.

When they screened other, similar fruit fly genes, though, the scientists found one that did.

After moving to Berkeley, he arrived at a career crossroads in 1994, when Spyros Artavanis - Tsakonas, then at Yale, discovered and subsequently patented the human relative of the fruit fly gene notch, which plays a role in cell - to - cell interactions and could be an anti-cancer target.

Most of the rechristened genes were identified by geneticists studying the fruit fly; when equivalent genes were later found in the human genome, researchers simply continued using the name of the fruit fly gene to avoid confusion.

Collins and Anthony James of the University of California, Irvine, thought they might use the mutant bug to test a fancy trick: Take a bit of DNA, called a transposon, that likes to wiggle into genomes, and use it to insert a fruit fly gene for darker eye color into a mosquito's DNA.

For instance, one protein produced by a key fruit fly gene serves two separate functions over the course of fly development.

«Plants modified to express fruit fly gene used to detoxify contaminated land.»

Now, he has another claim on immortality: Geneticists have named a newly discovered fruit fly gene in his honor.

Researchers have found that a small change in a fruit fly gene affects the frequency at which they sing to their mates, Ars Technica reports.

In 2000, behavioral geneticist Ulrike Heberlein of the University of California, San Francisco, found that mutations in a fruit fly gene that disrupts the synthesis of their version of the neurotransmitter noradrenaline dampen a fruit fly's ability to acquire tolerance to ethanol.

In the study, Spradling, with colleagues Michael Buszczak and Shelley Paterno, determined that the fruit fly gene scrawny (so named because of the appearance of mutant adult flies) modifies a specific chromosomal protein, histone H2B, used by cells to package DNA into chromosomes.

For example, they found that the genes cut and numb, among others, influence the identity and type of neurons made by their progenitors, and that the fruit fly gene atonal is implicated in vision and hearing.

Not exact matches

As informative as the bunker studies are, to investigate the genes that underlie the biological clock scientists had to turn to fruit flies.

Together with Christian Schlötterer, the Head of the Institute, and other colleagues, Nicola Palmieri investigated the genes in a European species of fruit fly (Drosophila pseudoobscura).

An exciting prospect for the future involves the recovery of an entire system of clock - regulated genes in organisms such as fruit flies and mice.

Orphan genes were first discovered in the fruit fly but are found in all organisms, including man.

The less adept mice, Rubin's team found, carry extra copies of a previously known human gene called DYRK; a mutated version of an almost identical gene in fruit flies, called minibrain, causes neurological defects.

So they engineered fruit flies» genes to enhance or repress the activity of Rac in their brains and taught them to associate a smell with an electric shock.

«Variation at a central metabolic gene influences male fruit fly lifespan.»

Bingwei Lu, a neuroscientist at Stanford University in California, has shown that a microRNA sequence which suppresses certain genes is linked to the death of brain cells in fruit flies.

Her team found a gene, which they have since dubbed happyhour, that makes fruit flies sensitive to booze.

A team of scientists led by the University of Birmingham has shown how a common mRNA modification, N6 - methyladenosine (m6A), regulates gene expression to determine the sex of fruit flies.

Data published by the International Human Genome Sequencing Consortium indicate that somewhere between 113 and 223 genes present in bacteria and in the human genome are absent in well - studied organisms — such as the yeast Saccharomyces cerevisiae, the fruit fly Drosophila melanogaster and the nematode Caenorhabditis elegans — that lie in between those two evolutionary extremes.

But a new study, published today in Nature, has revealed that m6A plays a key role in the regulation of the Sex - lethal (Sxl) gene, which controls sex determination of the fruit fly Drosophila.

«Knocking down the expression of this gene is lethal for fruit flies — male and female,» said Anholt, who also directs NC State's W.M. Keck Center for Behavioral Biology.

The overexpression of an important gene that regulates energy metabolism can cause a severe shortening of lifespan in male fruit flies but has only a small negative effect on lifespans of female fruit flies, according to new research from North Carolina State University.

«Our study validates using fruit flies as a model to discover new genes that may also control aggression in humans.»

Fruit flies with the mutant form of LRRK2 also had a disrupted microRNA pathway associated with the gene, and accumulated toxic proteins that killed motor - coordinating neurons in the brain.

In today's issue of Cell, a team reports that it has found in mice and humans a close relative of a fruit fly clock gene — the first evidence that some of these genes may have been conserved over the course of evolution.

Our team showed that the same common gene is critical to building limbs in humans and fruit flies.

Together, the researchers focused on a family of genes that encode taste receptors found in fruit flies.

The quest was to figure out how these genes sculpted the fruit fly body form.

I was looking around for insights when I came across the very thin literature on the genes that sculpt fruit fly bodies, including the study of spectacular mutants.

Just as we were getting started, it became clear from our research and others» that these body - building genes were not restricted to fruit flies; they were shared throughout the animal kingdom.

Molecular geneticist Cheng Chi Lee, developmental biologist Gregor Eichele, and their co-workers at the Baylor College of Medicine in Houston have isolated a gene in mice and humans that shares 44 % of the amino acid sequence of the period (per) gene of the fruit fly Drosophila melanogaster.

They downloaded sequences of more than 700 genes from organisms ranging from fruit flies to humans and compared genes from closely related species.

Dr Elliott said: «The treatment of fruit flies carrying the faulty LRRK2 gene with UDCA showed a profound rescue of dopaminergic signalling.

The researchers also found that cockroaches have genes that allow them to regrow broken limbs — the same genes present in other insects, including the fruit fly.

«Same switches program taste, smell in fruit flies: Findings help explain how complex nervous systems arise from few genes.»

It either turned off one of 195 genes that arose in fruit flies less than 35 million years ago, or one of 245 genes from further back.

In March, researchers from the University of California, San Diego reported online in Science that they had created a gene drive in fruit flies.

Already, researchers have used CRISPR / Cas9 to edit genes in human cells grown in lab dishes, monkeys (SN: 3/8/14, p. 7), dogs (SN: 11/28/15, p. 16), mice and pigs (SN: 11/14/15, p. 6), yeast, fruit flies, the worm Caenorhabditis elegans, zebrafish, tobacco and rice.

A gene drive turned normal fruit flies (A) into yellow flies (B).

The technology has been developed in recent years in fruit flies, mosquitoes and other organisms, using CRISPR gene editing.

«I'm not used to that kind of conference,» says Messer, who says he told the group about his lab's efforts to study the evolution of resistance to CRISPR gene drives in fruit flies.

Researchers working in the Development and Growth Control Lab at IRB Barcelona reveal that the Dpp gene (BMP in humans) plays a double role in the structural organisation and growth of the wings of the fruit fly Drosophila melanogaster.

A subset of such genes, known as Hox genes, is found across the animal kingdom, in humans as well as fruit flies.

It wasn't immediately apparent how the gene regulated fruit fly activity.

In a series of experiments sparked by fruit flies that couldn't sleep, Johns Hopkins researchers say they have identified a mutant gene — dubbed «Wide Awake» — that sabotages how the biological clock sets the timing for sleep.