Sentences with phrase «full impact of a development»

-- Require «Resource Impact Statements» that will detail the full impact of a development on all resources and services.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Guy Timberlake, chief executive officer of the American Small Business Coalition, said the full impact of the decision is unclear, but that it seems to invalidate elements of the small disadvantaged business program and the federal contracting component of the 8 (a) business development program.

A distinction of greater consequence was in process of development during these years, but its full impact upon the work of the minister was not to be felt until a later period.

«One example of how full service has impacted our fast - casual business is we have a culinary development team now that's focused on homing in on Currito's recipes — innovating, adjusting, and tinkering them,» Joe Lanni says.

This includes Corporate Social Investment, whereby the group promotes the development of learners through three academies which offer holistic, full - year programmes centred around sport, art and education; Entrepreneur Development which focuses on skills - based entrepreneurial development through its Tsogo Sun Book a Guesthouse and Supplier Development programmes; and Environmental Education, committed to initiatives that reduce the impact the business has on the edevelopment of learners through three academies which offer holistic, full - year programmes centred around sport, art and education; Entrepreneur Development which focuses on skills - based entrepreneurial development through its Tsogo Sun Book a Guesthouse and Supplier Development programmes; and Environmental Education, committed to initiatives that reduce the impact the business has on the eDevelopment which focuses on skills - based entrepreneurial development through its Tsogo Sun Book a Guesthouse and Supplier Development programmes; and Environmental Education, committed to initiatives that reduce the impact the business has on the edevelopment through its Tsogo Sun Book a Guesthouse and Supplier Development programmes; and Environmental Education, committed to initiatives that reduce the impact the business has on the eDevelopment programmes; and Environmental Education, committed to initiatives that reduce the impact the business has on the environment.

In a series of separate public hearings this fall, members of Congress and New Mexico state legislators heard testimonies from the full range of people who have something to say about uranium mining — community members aggrieved by six decades of mining impacts, industry officials trumpeting new jobs from renewed uranium activity, and government regulators trying to figure out how to address both the past uranium legacy and future uranium developments.

I encourage you to read the full CRUK Science Update Blog post «High - impact science: Hedgehogs, flies and skin cancer — the story of vismodegib», it's an excellent example of how research on flies, rodents and a range of other organisms combined with studies of cancer genetics in humans to enabled the development of an innovative therapy.

Included in this resource: Definitions and Key terms about Globalisation Features of Globalisation Real world impacts on the 2008 Financial Crisis Full Key Comparison of the benefits and drawbacks of globalisation e.g. Increased Competition, Export Opportunities, Development e.g. Environmental Market Failure, Consumer Choice, Unemployment DO N'T FORGET TO REVIEW!

Provides full details of the National Professional Development Evaluation Study, including teacher impact and student impact.

To give evaluators a full and complete understanding of the impact Seesaw has on student learning, its ability to document student growth and development over time, and its capacity to strengthen the home / school connection, we strongly recommend Burlington teachers make their evaluator a co-teacher in their Seesaw class (es).

[Working full time jobs] has impacted development far more than I anticipated at the outset of the project.

To apply for a full fellowship, please submit up to 10 images (slides or jpegs on cd) of your work, resume / bio and a statement explaining how this will impact your development as an artist by May 1.

From the crews romp at Rios Tropicales, a Costa Rican low - impact river rafting company supporting the sustainable development of a local community, to their flight on Nature Air to destination Leatherback Trust, an organization working to protect the leatherback turtles nesting on the beaches around Playa Grand — it's an adventurous read chock full of inspiring companies and people making a difference.

Politicians and business leaders must make full economic calculations of the impact of the new Little Ice Age on everything — industry, agriculture, living conditions, development.

The resolution called for one panel discussion on identifying challenges and ways forward towards the realization of all human rights for all, including the right to development, in particular those in vulnerable situations, as well as the measures and best practices to promote and protect human rights that can be adopted by States in addressing the adverse effects of climate change on the full and effective enjoyment of human rights, and another panel discussion on how climate change has had an adverse impact on States» efforts to progressively realize the right to food, and policies, lessons learned and good practices.

The impact statement, released Dec. 20, is an overview of possible impacts to full - scale oil shale development on nearly 2 million acres in the three states.

Very shortly, the full impact of the Legal Services Act 2007 will see the injection of capital from outside investors, which the government hopes will increase funds for the development of technological systems and processes and improve the quality and choice of legal services offered to consumers.

Certified as a Real Estate Specialist by the State Bar of Arizona, his practice involves the full range of real estate entitlements including zoning, general plan amendments, specific area plan approvals and amendments, interpretations, variances, use permits, subdivision and site plan approvals, annexation, development agreements, construction permits, development impact fees, real estate transactions, right - of - way abandonments and other development - related matters.

Only third parties experiencing a first hand impact on a right or serious interest relating to competition can challenge consent agreements, the Competition Tribunal ruled in Burns Lake Native Development Corporation v. Commissioner of Competition and West Fraser Timber Co. Ltd. [more] Full article

«Sometimes children and adolescents feel sad, anxious, and overwhelmed by changing life situations, which may impact the development of their full academic, emotional and social potential.

First, is whether the NIC Principles pay sufficient regard to the full range of social, economic, cultural and political factors that impact on development outcomes in Indigenous communities.

Early diagnosis and intervention for children with FASD are thought to be key to preventing behavioural, mental health and learning difficulties.36 — 38 However, Fitzroy Valley community members have reported that a current lack of diagnostic and intervention support for children with FASD impacts their children's ability to reach their full potential.14 Children with FASD need access to interventions which support their development of emotional and behavioural regulation skills.38 It is recognised that educators, alongside the family, play a crucial role in supporting children with FASD to improve life outcomes through contextually appropriate and evidence - based interventions.36 While there is limited evidence for strategies that can assist children affected by FASD, 2 particularly to improve self - regulation and executive functioning skills, 8 17 32 39 the Alert Program for Self - Regulation has evidence to suggest it is a promising intervention.17 39

This full - day workshop examines the social emotional needs of babies and toddlers; the impact of stress on early childhood brain development; and the implications of complicated deployments, parental injury, and parental loss for very young children.

This document is also available in pdf format (180k) This research findings is one of four & accompanied with a full report (GUS) The circumstances of persistently poor children, (GUS) Health inequalities in the early years, research findings 2/2010, (GUS) Maternal mental health & its impact on child behaviour & development, research findings 3/2010, (GUS) children's social, emotional & behavioural charactoristics at entry to primary school, research findings 4/2010

An evaluation of the long - term impact of the Chicago Child - Parent Centers, for example, showed that children attending the program for a full day scored better on measures of social - emotional development, math and reading skills, and physical health than similar children attending the program part day.Arthur Reynolds et al. «Association of a Full - Day vs. Part - Day Preschool Intervention with School Readiness, Attendance, and Parent Involvement,» JAMA 312, no. 20 (2014): 2126 — 2full day scored better on measures of social - emotional development, math and reading skills, and physical health than similar children attending the program part day.Arthur Reynolds et al. «Association of a Full - Day vs. Part - Day Preschool Intervention with School Readiness, Attendance, and Parent Involvement,» JAMA 312, no. 20 (2014): 2126 — 2Full - Day vs. Part - Day Preschool Intervention with School Readiness, Attendance, and Parent Involvement,» JAMA 312, no. 20 (2014): 2126 — 2134.

pay sufficient regard to the full range of social, economic, cultural and political factors that impact on development outcomes in Indigenous communities;

full information is provided about the scope and impacts of the proposed development activities on their lands, resources and well - being

Recently Florida's largest private landowner, the St. Joe Company, took REM on a tour of its developments along the Gulf to show how, despite the impact of the real estate crisis in the U.S., several of the company's new developments are moving ahead full - steam.

This gives me an idea as to the percentage of time I need to devote to marketing, networking and business development,» said Peter Metzner, president of Dynamic Change, a leadership and team development firm in Chapel Hill, N.C. «If my pipeline is full and I neglect business development, I usually will see the impact within the next quarter.»