Sentences with phrase «fully human monoclonal antibody»

Key Highlight: • Facilitated the introduction of HUMIRA (adalimumab) for the healthcare professionals as the latest and the only fully human monoclonal antibody against TNF for the treatment of moderate to severe psoriasis in patient failed at least on two DMARD's.
Guselkumab, a fully human monoclonal antibody targeting IL - 23, in this Phase 2 study for the treatment of PsA, was well tolerated with no unexpected safety findings in this patient population.2 Guselkumab is now being pursued in a Phase 3 development programme for psoriatic arthritis.
Dupilumab, a fully human monoclonal antibody discovered by Regeneron Pharmaceuticals and being developed by Regeneron and Sanofi, thwarts activation of the Th2 immune response implicated in asthma by blocking two cytokines, interleukin - 4 and interleukin - 13.
Denosumab, a fully human monoclonal antibody drug, binds specifically to RANK - ligand (RANKL) and inhibits osteoclast - induced bone resorption by preventing the binding of RANKL to RANK.

Not exact matches

Dr. Caskey and her team describe the first in human, phase 1 clinical trial of a first in class fully human highly neutralizing anti-HIV monoclonal antibody.
A fully human, well tolerated monoclonal antibody, if formulated for long duration may be a very attractive alternative to daily PrEP oral treatment for some individuals.
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