Sentences with phrase «function at»

«Our research focuses on the development of reforming catalysts that can be applied to a host of technologies, such as biomass gasification, pyrolysis, and natural gas — and will further the understanding for how catalysts function at the molecular level,» said Robert Dagle, who led this experimental research at PNNL.

The upper extremity motor score (UEMS), is a scale used to quantify motor function at each of five upper extremity muscle groups driving arm and hand function; these scores are also used to determine «motor levels,» which define the level within the cord above which a subject has normal function.

The fact that cognitive impairments were seen at the pre-plaque stage, where Aβ could be detected intraneuronally (by IHC) and in CSF (by MALDI - MS), suggests that a combination of intraneuronal and soluble extracellular Aβ may be responsible for impairing neuronal function at early time points.

Our study demonstrates the power of combining the BD AbSeq technology with RNA - seq to gain a more comprehensive understanding of cell lineage and function at the single - cell level.

In the 1960s, groundbreaking experiments by David Hubel and Torsten Wiesel and other «mapmakers of the mind» inspired a generation of scientists to explore brain function at the cellular level.

We use neuronal cultures, induced pluripotent stem (iPS) cells and transgenic and gene - targeted mouse models to study the differential effects of apoE3 and apoE4 on cell signaling pathways and cytoskelatal structure and function at molecular, cellular and behavioral levels.

All patients survived with stable renal function at month 12 and no chimerism was detectable at month 3.

«RITS might be exerting its effect at centromeres through Ago1 and the RNAi machinery, but might enforcing its function at the telomeres through Chp1 and its PIN domain.»

Recently, Pang and his team found that though cone degeneration in Rpe65 - deficient mice begins by 14 days after birth, a few cones in the peripheral dorsal and temporal quadrants of the retina still function at five weeks and perhaps later, when virtually all other cones are degenerated.

We analyzed the role of DNM2 and several actin binding proteins on clathrin plaque function at costameres in vitro by using either siRNA depletion combined to high resolution electron microscopy or in vivo by intravital microscopy.

It concentrates on analysis of gene function at all levels: the gene and its product, the cell and cellular interactions, embryonic tissues and the entire animal.

This discovery could pave the way for the rational design of 2D superconducting devices that function at relatively high temperatures.

Immunophilins are now known to function at the crossroads of protein folding and trafficking, and signal transduction.

I will also explore BIN1 function at the cellular level using in vitro techniques coupled with high resolution imaging.

Using our detailed insights into how the brain circuitry is organized, both globally and locally, makes it possible to describe brain function at a computational level.

These devices can also function at higher operating temperatures and in high radiation environments such as space.

The American Journal of Physiology - Heart and Circulatory Physiology focuses on the physiology of the heart, blood vessels and lymphatics, including experimental and theoretical studies of cardiovascular function at all levels of organization ranging from the intact animal to the cellular, subcellular and molecular levels.

«The most interesting thing about these materials is they function at temperatures above 500 degrees Celsius,» says MIT graduate student Jessica Swallow, pictured with the equipment used for testing the new materials.

«The most interesting thing about these materials is that they function at temperatures above 500 degrees Celsius,» Swallow explains.

«We now plan to apply this technology to dissect the process of invasion and understand what genes and proteins function at what step,» Rayner says.

«By linking fisheries to ecology, we can now make informed statements about ecosystem function at a given level of fish biomass.»

To find out, the researchers at Fraunhofer IAF developed a mathematical model that describes how radio frequency circuits should be designed if they are to function at extremely low temperatures.

Previous research has shown that blood vessels tend to contract at high altitude, so researchers decided to see if they could improve blood vessel function at high altitude simply by having test subjects drink beet juice.

This program, McKnight Technological Innovations in Neuroscience Awards, focuses on «how technology may be used or adapted to monitor, manipulate, analyze, or model brain function at any level, from the molecular to the entire organism.»

In a related Comment published today in The Lancet, Jonathan Barasch, MD, PhD, professor of medicine and pathology and cell biology at CUMC, and colleagues Drs. Joseph Bonventre (Harvard Medical School, Brigham and Women's Hospital) and Richard Zager (University of Washington Medicine) explain that the blood test, which measures serum creatinine — a waste product that is removed by the kidneys and excreted in urine — only offers a snapshot of the kidney's function at a given moment, which can vary depending on individual factors such as body size and muscle mass.

Of the participants, 69 had normal cognitive function at the start of the study, 52 had been recently diagnosed with mild cognitive impairment, and 31 were diagnosed with Alzheimer's disease.

Finally, the study provides an example of a highly integrative approach to understanding brain function at multiple scales, «linking genes and gene networks to the properties of single neurons and populations of neuron subtypes, all the way up to the level of animal behaviors,» said Okaty.

The FMT arm also demonstrated sustained and significant improvements in cognitive function at 1 year compared with both baseline and SOC.

The original, randomized, open label study, which enrolled 20 outpatient men with cirrhosis and recurrent HE receiving standard - of - care (SOC) treatment, had previously reported that a single FMT enema after antibiotic pretreatment improved cognitive function at Day 20 and reduced HE episodes and hospitalizations over the following 5 months compared with SOC.1 The long - term outcomes of this study, which were presented today at The International Liver Congress ™ 2018 in Paris, France, demonstrated sustained and statistically significant reductions in the number of HE episodes and hospitalizations as well as improvements in cognitive function over 1 year in the men who received FMT compared with the control group.

All participants completed questionnaires to assess their levels of fatigue and physical function at the start of the trial and at 12 weeks, roughly 4 weeks after the GES guidance with the physiotherapist had ended.

And since the acidic proteins are able to function at a much wider pH range than suspected, the scientists say that corals can continue to build reefs, even as the ocean acidifies.

«Social institutions would function at a better level if we could get rid of all these negative potential effects.»

«If it were possible to repeat lung function at one time only, the best time would be around age 25, when lung growth peaks.»

Future studies will be devoted to elucidate how Hox genes perform this protective function at the molecular level.

In «Neonatal Caffeine Treatment and Respiratory Function at 11 Years in Children,» Dr. Doyle and colleagues report on their study to determine if the lung benefits of caffeine in premature babies persist in mid-childhood.

Thirty - one years ago, Gould and Vrba suggested that repetitive DNA sequences known as transposons, which originated from viruses, might serve no direct function at first, but may be used to great advantage later on.

A lack of light in the morning can diminish the biological chain reaction and make many of us feel below par and not function at full throttle.

To understand how DIXDC1 mutations put normal brain function at risk, Cheyette's team turned to mutant mice that lacked a functioning copy of the gene.

«Children who had low lung function at the start of the trial followed a series of predicted growth patterns: most had reduced lung growth with time and a significant number would go on to meet the criteria for COPD.»

«We need to know how it will function at the full scale,» he says.

Dr. Butler - Dawson and her team are focusing future research on delving deeper into understanding the factors that contribute to declining kidney function, such as why workers who live closer to the sugarcane field are more likely to have impaired kidney function at the end of the harvest season.

In addition to low lung function at the start of the study, being male also predicted worse outcomes, but this is likely a consequence of higher asthma prevalence in boys.

In mid-February, Spine published a Pitt / UPMC research project showing the early addition of manual - thrust manipulation leads to significantly greater reductions in low - back pain and improved function at four weeks.

The work has highlighted a potential link to environmental contaminants, after they were able to demonstrate that chemicals found in the sperm and testes of adult dogs — and in some commercially available pet foods — had a detrimental effect on sperm function at the concentrations detected.

The meaning of life, in this view, is making that system function at ever - higher «levels of description.»

The participants answered questionnaires about sexual function at the outset and every three months during the 12 - month study.

More knowledge of the basic function of auxin is in itself important to the life sciences: how plants function at various levels, from cell to organs and as a whole.

How will they function at parties if they can't protect themselves from salvers of appetizers with a theatrically pale and desperate wave of the hand?

«We're trying to determine the threshold for getting the most function at the most affordable cost.

Researchers in China have developed a battery with organic compound electrodes that can function at -70 degrees Celsius — far colder than the temperature at which lithium - ion batteries lose most of their ability to conduct and store energy.