Not exact matches
The coordinated assembly and disassembly
of actin in the cell cortex, which lies just beneath the plasma membrane, generates cortical
actin waves that are crucial for important cell
functions including migration and cell polarity.
Penn Vet researchers showed that differences in the order
of nucleotides — not the amino acids — governed the distinct
functions of two forms
of actin.
Structure /
Function Analysis
of the Interaction
of Phosphatidylinositol 4, 5 - Bisphosphate with
Actin - capping Protein.
Itk
functions to control
actin polymerization at the immune synapse through localized activation
of Cdc42 and WASP.
We analyzed the role
of DNM2 and several
actin binding proteins on clathrin plaque
function at costameres in vitro by using either siRNA depletion combined to high resolution electron microscopy or in vivo by intravital microscopy.
The inflammasome adaptor ASC regulates the
function of adaptive immune cells by controlling Dock2 - mediated Rac activation and
actin polymerization.
Interference with
actin dynamics is superior to disturbance
of microtubule
function in the inhibition
of human ovarian cancer cell motility.
Defects in nuclear
actin polymerization and myosin motor
function result in heterochromatin repair defects and widespread chromosome rearrangements, revealing the importance
of the relocalization pathway in genome integrity.
Senior author
of the study Xuetong «Snow» Shen, Ph.D., associate professor in The University
of Texas MD Anderson Cancer Center Department
of Molecular Carcinogenesis, developed a unique model system to nail down
actin's
function in the nucleus: the
actin - containing INO80 chromatin remodeling complex in yeast cells.
At long last, one
of actin's key nuclear
functions was uncovered.
Study Uncovers
Actin's Action in the Nucleus (03/25/2013) The function of nuclear actin has stumped scientists for several dec
Actin's Action in the Nucleus (03/25/2013) The
function of nuclear
actin has stumped scientists for several dec
actin has stumped scientists for several decades.
Actin dynamics and organisation are tightly regulated processes responsible for the range
of different and specific cellular
functions in response to various stimuli.