«A prominent and well - characterized feature of AD is progressive, region - specific declines in the cerebral metabolic rate of glucose (CMRglc)-LSB-...] Carriers of a common Alzheimer's susceptibility gene [APOE Ɛ4] have
functional brain abnormalities in young adulthood, several decades before possible onset of dementia.
Dr. Jogia won the award for his work on
the functional brain abnormalities associated with reward and working memory processing in Bipolar Disorder.
Associations between circadian activity rhythms and
functional brain abnormalities among euthymic bipolar patients: a preliminary study.
Not exact matches
I am proposing a demanding criterion: that you be able to detect
abnormalities in patients beforehand by such
brain - imaging techniques as
functional MRI [which measures blood flow in the
brain], and then use imaging to see whether or not there is a change in those markers for the disease as the therapy progresses.
While those studies uncovered widespread
functional and anatomical
brain abnormalities in ASD, the results were not highly consistent, possibly reflecting the complex
brain pathology in autism spectrum disorders.
The researchers found a link between
abnormalities in white matter and a decrease in
functional connectivity in the
brain's default - mode network, a set of regions that typically shows abnormal behavior in people at genetic risk for Alzheimer's disease.
It is hoped that the delivery of the missing SGSH gene provides a permanent source of
functional enzyme in the
brain that reverses phenotypic
abnormalities of CNS neural cells.
One of the lab's goals is to improve the understanding of
functional, structural, and neurochemical
brain abnormalities in depression.
MRI, positron emission testing (PET scan),
functional MRI, computerized tomography (CT scan) and / or single photon emission computed tomography (SPECT) to look for scar tissue or other
brain abnormalities that may be causing seizures
An important area for future work will be to understand
functional connectivity
abnormalities in ASD at the global level, across the whole
brain, as well as in specific
functional networks or sets of nodes.
Supporting evidence for our findings comes from studies reporting on decreased default mode
functional connectivity in combination with studies reporting on degenerative
brain abnormalities in the cingulum bundle.
Furthermore, several multimodal
brain imaging results point to anatomo -
functional abnormalities in the STS in both children and adults with ASD.