Sentences with phrase «functional engraftment»

Not exact matches

Central role for disabled - 2 in mesenchymal stem cardiac protein expression and functional consequences after engraftment in acute myocardial infarction.

«The ability to form functional vascular networks in 3D tissues before they are implanted not only enables thicker tissues to be formed, it also raises the possibility of surgically connecting these networks to the natural vasculature to promote immediate perfusion of the implanted tissue, which should greatly increase their engraftment and survival.»

Some of the recognized challenges are poor engraftment of implanted cells and, in the case of human cardiomyocytes, functional immaturity and lack of electrical integration, leading to limited contribution to the heart's contractile activity and increased arrhythmogenic risks.