Sentences with phrase «functional genomics studies»

Not exact matches

The study is the culmination of 12 years of collaboration and combines the French team's expertise in cloning and reproductive biology with the U.S. team's expertise in functional genomics.

Methods employed in cognitive neuroscience include psychophysical experiments, functional neuroimaging, electrophysiological studies of neural systems and, increasingly, cognitive genomics and behavioral genetics.

She stayed on as a postdoc in the same microbiology group and now studies the functional genomics and bioenergetics of Saccharomyces cerevisiae to improve its use in winemaking.

I realize that your «Working Group On Review Of Bioengineering And Technology And Instrumentation Development Research», defined «bioengineering and technology» as encompassing areas such as biotechnology, functional genomics, informatics, chemistry and physics, nevertheless they did not discuss the problems experienced by physicists engaged in basic research on the frontier of physics and biology from the present system of study sections.

Included are studies of physiological ecology, evolutionary physiology, stress physiology, functional morphology and movement, animal sensation, computational and systems neuroscience, and environmental genomics.»

Research builds on a series of recent landmark studies, at JCVI, which have led to transformative new methodology for synthetic biology and functional genomics

We expect that this genomic level study will contribute to linking functional diversity and phylogenetic diversity within the dominant bacterial grazers in the oceans.

The INFRAFRONTIER mission: ◊ to shape the European Research Area in the field of mouse functional genomics and thereby make an important contribution to the study of human disease.

The perspectives are to upgrade the scale of the functional genomic screen to a genome wide study to get an highlight of all of the biological networks relevant to be targeted for DM1.

My ultimate career goal is to enjoy a hybrid position that involves directing a diagnostic laboratory while also performing functional studies dedicated to improving and expanding the identification of pathological genomic variants by leveraging the above research paradigm.

Because alleles found to be mutated only once in 5,338 tumors rendered cells tumorigenic, these observations underscore the value of integrating genomic information with functional studies.

Ageing research and more generally the study of the functional basis of human diseases profit enormously from the large - scale approaches and resources in mouse functional genomics: systematic targeted mutation of the mouse genome, systemic phenotyping in mouse clinics, and the archiving and distribution of the mouse resources in public repositories.

«EnhancerFinder is a machine - learning algorithm that takes in basic genetic information — a HAR sequence, known evolutionary patterns, other functional genomics data — and returns a prediction of that HAR's function,» explained Tony Capra, PhD, the study's lead author.

Our research combines diverse techniques ranging from genomics, computational biology, tumour imaging, in vitro and in vivo functional models to study biological and clinical phenotypes.The proteins produced by these genes may serve as targets for novel chemotherapy drugs and other cancer treatments, or imaging scans.

These studies showed not just proof of concept of a new technology, but a spectacular jump in what is possible within functional genomics.

This section invites manuscripts describing (a) Linkage, association, substitution or positional mapping and epigenetic studies in any species; (b) Validation studies of candidate genes using genetically - engineered mutant model organisms; (c) Studies focused on epistatis and gene - environment interactions; (d) Analysis of the functional implications of genomic sequence variation and aim to attach physiological or pharmacogenomic relevance to alterations in genes or proteins; (e) Studies of DNA copy number variants, non-coding RNA, genome deletions, insertions, duplications and other single nucleotide polymorphisms and their relevance to physiology or pharmacology in humans or model organisms, in vitro or in vivo; and (f) Theoretical approaches to analysis of sequence varstudies in any species; (b) Validation studies of candidate genes using genetically - engineered mutant model organisms; (c) Studies focused on epistatis and gene - environment interactions; (d) Analysis of the functional implications of genomic sequence variation and aim to attach physiological or pharmacogenomic relevance to alterations in genes or proteins; (e) Studies of DNA copy number variants, non-coding RNA, genome deletions, insertions, duplications and other single nucleotide polymorphisms and their relevance to physiology or pharmacology in humans or model organisms, in vitro or in vivo; and (f) Theoretical approaches to analysis of sequence varstudies of candidate genes using genetically - engineered mutant model organisms; (c) Studies focused on epistatis and gene - environment interactions; (d) Analysis of the functional implications of genomic sequence variation and aim to attach physiological or pharmacogenomic relevance to alterations in genes or proteins; (e) Studies of DNA copy number variants, non-coding RNA, genome deletions, insertions, duplications and other single nucleotide polymorphisms and their relevance to physiology or pharmacology in humans or model organisms, in vitro or in vivo; and (f) Theoretical approaches to analysis of sequence varStudies focused on epistatis and gene - environment interactions; (d) Analysis of the functional implications of genomic sequence variation and aim to attach physiological or pharmacogenomic relevance to alterations in genes or proteins; (e) Studies of DNA copy number variants, non-coding RNA, genome deletions, insertions, duplications and other single nucleotide polymorphisms and their relevance to physiology or pharmacology in humans or model organisms, in vitro or in vivo; and (f) Theoretical approaches to analysis of sequence varStudies of DNA copy number variants, non-coding RNA, genome deletions, insertions, duplications and other single nucleotide polymorphisms and their relevance to physiology or pharmacology in humans or model organisms, in vitro or in vivo; and (f) Theoretical approaches to analysis of sequence variation.

Laboratory activities minimally include performing a lab - based patient - oriented research project applicable to cancer genomics, with an emphasis on mastering techniques commonly used within a human genetics laboratory, such as PCR, gene sequencing, mutation analysis, western blots, and functional protein studies.

To improve fuel production titer, rate, and yield (TRY), we study the producing host and fuel biosynthesis pathway intensively using various functional genomics tools such as targeted proteomics, metabolomics, and transcriptomics, and engineer the metabolic pathway in the producing host using synthetic biology tools and systems biology.

Genomic studies, which in principle group together co-regulated genes, can potentially identify new components of known regulatory pathways in ES cells that can subsequently be explored in functional studies.

To investigate the underlying mechanisms, we undertook (1) bioinformatic, functional genomic annotation and human osteoblast expression studies; (2) gene - function prediction; (3) skeletal phenotyping of 120 knockout mice with deletions of genes adjacent to lead independent SNPs; and (4) analysis of gene expression in mouse osteoblasts, osteocytes and osteoclasts.

We apply personalised functional genomics to study diseases in patient - derived cells using systematic and targeted approaches to unravel mechanisms and discover novel treatments (see video).