«What has emerged from our study as well as from other work on introgression is that interbreeding with archaic humans does indeed have
functional implications for modern humans, and that the most obvious consequences have been in shaping our adaptation to our environment — improving how we resist pathogens and metabolize novel foods,» Kelso says.
Our work on pyrmidine de novo synthesis and other pathways is also leading not only to structures, but
also functional implications and characterization of interaction between the enzymes and their inhibitors.
The strong association of rs117026326 with SLE and
the functional implications of nearby NCF1 took the team to their next hypothesis: that the rs117026326 SNP might tag causal variants of NCF1 that were not present in the 1000 Genomes Project database.
The approach, which was validated in well - known contexts, can now be used for more reliable protein structure predictions as well as to shed light on
the functional implications of structural domains.
«It has the potential to open a whole new set of studies into
the functional implications of interspecies interactions.»
To investigate the evolutionary and
functional implications of their observations, the researchers assembled a large dataset containing information on extinct and extant fishes.
Surprises in Architecture and Gene Content, and Their Functional Implications
Structural analysis of arabinose -5-phosphate isomerase from Bacteroides fragilis and
functional implications.
«Systematic and
functional implications of the facial morphology of Australopithecus and early Homo.»
These groups of features may have
functional implications.