Benchmarking tools for the alignment of
functional noncoding DNA.
Benchmarking tools for the alignment of
functional noncoding DNA D.A. Pollard, C.M. Bergman, J. Stoye, S.E. Celniker, and M.B. Eisen BMC Bioinformatics (2004) 5:6 Correction Download entire paper in pdf format Download correction in pdf format
Candidate genes and
functional noncoding variants identified in a canine model of obsessive - compulsive disorder.
Not exact matches
This, in my opinion, is one of the most compelling parts of this study: in vivo
functional validation of a single base change in a
noncoding enhancer that's hundreds of thousands of bases away from the gene it regulates.
We know, of course, that
noncoding portions of the human genome contain
functional elements contributing to phenotypic variation.
Huang Y - F, Gulko B, Siepel A. Fast, scalable prediction of deleterious
noncoding variants from
functional and population genomic data.
Genome editing technology enables precise modification of individual protein coding genes, as well as
noncoding regulatory sequences, enabling the elucidation of
functional effects in human disease relevant cellular systems.