Sentences with phrase «functional polymorphism»
A functional polymorphism refers to a variation or difference in our genes that influences how our body functions. These variations can affect different aspects of our biology, such as our physical traits, metabolism, or the way we respond to certain medicines or diseases. Full definition
Most of the single nucleotide polymorphisms, including experimentally identified functional polymorphisms, are present at very low frequencies.
phys.org
However, whether this and other functional polymorphisms can affect neuroblastoma risk of Chinese children remains unknown.
Ortiz GJ, Li Y, Post SM, Pant V, Xiong S, Larsson CA, El - Naggar AK, Johnson DG, Lozano G. (2017) Contrasting effects of an Mdm2 functional polymorphism on tumor phenotypes.
Further, existing research has been limited to one or two functional polymorphisms at the expense of a more comprehensive assessment of the serotonin system.
FUNCTIONAL POLYMORPHISM IN THE BRAIN - DERIVED NEUROTROPHIC FACTOR GENE INTERACTS WITH STRESSFUL LIFE EVENTS BUT NOT CHILDHOOD MALTREATMENT IN THE ETIOLOGY OF DEPRESSION.
We explored the relationships between callous - unemotional traits and functional polymorphisms of selected serotonin - system genes, and tested the association between callous - unemotional traits and serum serotonin levels independently of antisocial and aggressive behaviour.
Functional polymorphism within the promotor of the serotonin transporter gene is associated with severe hyperkinetic disorders
A study of the interplay between peer drinking and the functional polymorphism rs1229984 in the alcohol dehydrogenase 1B gene (ADH1B) in the development of adolescent drinking milestones has found that peer drinking reduces the protective effects of an ADH1B variant.
A functional polymorphism in the promoter region of the human serotonin transporter gene (SLC6A4) has been associated with several dimensions of neuroticism and psychopathology, especially anxiety traits, but the predictive value of this genotype against these complex behaviors has been inconsistent.
Human Gene Mutation Database; published mutations causing or associated with human inherited disease; disease - associated / functional polymorphisms.
You can have what I call a functional polymorphism, where if you have a lot of oxidative stress, a lot of heavy metals, uhm — those can block or slow down those pathways, as well.
And you know, what people understand is that you - you may not have any copies of MTHFR, that you can have what I call a functional polymorphism where those pathways are not working because of too much oxidative stress, or environmental chemicals, or nutrient deficiencies.
The functional polymorphism of the monoamine oxidase A (MAOA) gene affecting enzyme activity moderated the relation between early maltreatment and later antisocial behaviour in males.
Association of Bax and Bcl - 2 Functional Polymorphisms and Protein Levels with Posttraumatic Stress Disorder
Association analysis between a functional polymorphism in the monoamine oxidase A gene promoter and severe mood disorders