Not exact matches
Yes, it's known that most higher
brain functions (such as perception, memory, and intelligence) are centered in the cerebral cortex, that 0.1 - inch - thick infolding of
neuron - rich gray matter overlaying both the right and the left hemispheres that would cover some 1.5 square feet if it were laid out like a tablecloth.
They say that drinking coke really ignites the creative
functions in their
brain by getting their
neurons firing at 100 %.
Far from endorsing a simple reduction of mind to mere
neurons, many neuroscientists are embracing paradigms that emphasize the holistic character of
brain function and the ways that reason and emotion interplay to make up a self.
What all these have in common is that, without any central control, individual units (genes, cells
neurons or workers) respond to simple, local information, in ways that allow the whole system (cells,
brains, organisms or colonies) to
function: the appropriate number of units performs each activity at the appropriate time.
For instance, motion pictures of living
brain cells taken through a microscope reveal tiny microglial cells that look like spiders and climb the trunks and branches of
neurons cleaning up debris and performing who knows what other
functions.
Myelin plays a key role in the health and
function not only of
neurons but the
brain and the rest of the nervous system, too.
DHA is being accumulated in the
brain of a child between the 26th and the 40th week of pregnancy and has a crucial influence on the
neuron functioning.
As they studied
brain activity in the knockout mice, the researchers also found prominent changes in a receptor in the
brain known as mGluR5 and other proteins that support the
function of
neurons and synapses, said co-lead author Xiaoming Wang, M.D., Ph.D., senior research associate in Duke's department of pediatrics.
However, little is known about how
neurons in this
brain region
function as gatekeepers.
But a detailed knowledge of how a single
neuron works and what are the
functions of the various parts of the
brain is not enough to give an answer to the initial question.
Further study revealed that these so - called immune proteins are actually present on the surface of certain nerve cells, but that they
functioned differently in the
brain than they did in the rest of the body; rather than scouting for germs, they influenced signals sent between
neurons.
Many of Markram's colleagues think that he is too ambitious, that a model of billions of
neurons, no matter how intricate, can not tell much about the
functions of a real
brain.
Until recently it has been difficult to study the role of glial cells in controlling appetite or any other
brain function, because scientists haven't developed many techniques for silencing or stimulating these cells, as they have for
neurons.
The cerebral cortex of the
brain is layered like an onion, with
neurons in different layers responsible for distinct levels of cognitive
function.
In the past, researchers have believed this executive
function was the job of single
neurons acting independently from one another — the
brain's version of a crowd of people in a large room all singing different songs in different rhythms and different keys.
The 2009 book The Playful
Brain: Venturing to the limits of neuroscience, for example, reviewed many studies showing that playful activity leads to the growth of more connections between neurons, particularly in the frontal lobe — the part of the brain responsible for uniquely human higher mental funct
Brain: Venturing to the limits of neuroscience, for example, reviewed many studies showing that playful activity leads to the growth of more connections between
neurons, particularly in the frontal lobe — the part of the
brain responsible for uniquely human higher mental funct
brain responsible for uniquely human higher mental
functions.
Seeking additional insight into similar mechanisms at work in other centers of the
brain, Donato and his team discovered that the signal to develop one area known to be involved in more abstract
functions, including memory and navigation, originated from deep within the
brain, in a specific population of
neurons that kicks off the maturation of an entire neural network.
To understand how they work, it's easiest to start from the beginning, in 1943, when neurophysiologist Warren McCulloch and mathematician Walter Pitts used math to describe the
function of
neurons in animal
brains.
The research, published in the current issue of the journal Science, demonstrates that
brain cells, known as astrocytes, which play fundamental roles in nearly all aspects of
brain function, can be adjusted by
neurons in response to injury and disease.
The protein is thought to destroy the
neurons in the
brain that make dopamine, a neurotransmitter that helps regulate a number of
functions, including movement and coordination.
One such drug — known as a Kv3 potassium channel modulator, in development by U.K. - based Autifony Therapeutics — may help improve
neuron function in the part of the
brain responsible for processing sounds.
In an era of increasing excitement about mapping the
brain's «connectome,» this finding fits with our growing understanding of complex
brain functions as residing not in discrete
brain regions, but in densely connected networks of
neurons spread throughout different parts of the
brain.
«Now, our goal is to see how this mechanism is affected in different
brain diseases and determine if it can be harnessed to protect
neurons and ultimately preserve
brain function.»
Astrocytes are star - shaped cells in our
brain that surround
brain neurons, and neural circuits, protecting them from injury and enabling them to
function properly — in essence, one of their main roles is to «baby - sit»
neurons.
Subplate
neurons form the first connections in the developing cerebral cortex — the outer part of the mammalian
brain that controls perception, memory and, in humans, higher
functions such as language and abstract reasoning.
Richard Rogers of the Pennington Biomedical Research Center at Louisiana State University and colleagues used a drug called fluorocitrate to knock out the
function of certain astrocytes and
neurons in the
brains of rats, blocking the sensation of hunger.
Motor
neurons, or nerve cells, in the
brain and spinal cord control the
function of muscles throughout the body.
Potentially explaining why even healthy
brains don't
function well with age, Salk researchers have discovered that genes that are switched on early in
brain development to sever connections between
neurons as the
brain fine - tunes, are again activated in aging neuronal support cells called astrocytes.
Although not nearly as well studied as
neurons, astrocytes — named for their star - shaped appearance — make up one - third to one - half of all the cells in the
brain and are increasingly being found to be critical for neuronal
function.
«We discovered that rhythmic oscillations of groups of
neurons in the prefrontal cortex — an area of the
brain involved in decision - making and executive
functions — controlled the strength of oscillations in
neurons of the neighbouring nucleus accumbens, an area involved in pleasure, reward and addiction,» says Liu.
«This is very useful because when the fiber is inserted into the
brain, it may affect the
function of
neurons very close to the fiber,» explained Ohayon.
«Ultrathin endoscope captures
neurons firing deep in the
brain: New fiber - based endoscope, tested in mice, poised to bring new insights into
brain function.»
The
neuron - packed
brain region — it's tucked underneath the cerebral hemispheres and plays a role in motor control and cognitive
functions, such as attention and language — seemed to stop aging at the 80 - year benchmark, which meant it remained fully functional but somehow impervious to deterioration of time for decades.
«It was particularly exciting to see plasticity in the
neurons impaired by mHTT,» said Davidson, noting that in the HD mice,
brain areas that had begun to atrophy recovered volume and permitted better motor
function after the researchers restored mTORC1 activity to more normal levels.
Last August in
Neuron, his team described organoids that survived for more than 20 months — long enough, analyses showed, for astrocytes to mature and
function in ways that mimic their real -
brain counterparts.
During development, subplate
neurons are among the first
neurons to form in the cerebral cortex — the outer part of the mammalian
brain that controls perception, memory and, in humans, higher
functions such as language and abstract reasoning.
The study published in Cell Metabolism reports a mechanism by which two types of
brain cells,
neurons and glia, normally support each other's
functions.
Neurons and the connections they make with one another, called synapses, are the keys to the
brain's
functions.
Researchers at Blue
Brain Project report groups of
neurons bound into such cavities provide the missing link between neural structure and
function, in their new study published in Frontiers in Computational Neuroscience.
Because mirror
neuron activity is thought to be a very basic part of
brain function — and it can be seen in many animals besides humans — the new finding supports the notion that our
brain is predisposed to distinguish «us versus them.»
«Uncovering the power of glial cells:
Brain implants can rely on more than
neurons to
function.»
Their end goal is to identify specific populations of
neurons in the fruit fly
brain that are necessary for emotion primitives — and whether these
functions are conserved in higher organisms, such as mice or even humans.
In an article recently published in the Journal of Neuroscience, University of Helsinki researchers establish that GDNF is an important physiological regulator of the
functioning of the
brain's dopamine
neurons.
Similarly, using light to stimulate atrophied
neurons that may be associated with schizophrenia could someday allow clinicians to repair cognitive
function, Boyden said, and enhance the flow of information through disordered
brain circuits that otherwise may be giving rise to delusions and paranoia.
The study supports the importance of the serotonin which is specified and maintained by a specific gene, the Pet - 1 gene — for normal
functioning of the
neurons, synapses and networks in the cortex, as well as proper development of
brain circuitry.
Under ordinary circumstances, the protein tau contributes to the normal, healthy
functioning of
brain neurons.
«The
brain and the gut are linked, so it's not too surprising that the health of the gut can impact the
functioning of
neurons,» says Jun Sun, associate professor of gastroenterology and hepatology at UIC and corresponding author of the paper.
The study found that after oral feeding, ground cinnamon is metabolized into sodium benzoate, which then enters into the
brain, stops the loss of Parkin and DJ - 1, protects
neurons, normalizes neurotransmitter levels, and improves motor
functions in mice with PD.
There are two camps for explaining the weak performance of artificial intelligence: Either we do not know enough of the fundamental principles of
brain function, or we have not simulated enough
neurons working together.
If the new mechanism also operates in the human
brain and can be potentiated, this could become of clinical importance not only for stroke patients, but also for replacing
neurons which have died, thus restoring
function in patients with other disorders such as Parkinson's disease and Huntington's disease,» says Olle Lindvall, Senior Professor of Neurology.