Sentences with phrase «functions of acetylcholine»

Not exact matches

Specifically, intensive postmortem neurological studies of their brain tissues reveal a relatively low density of acetylcholine (a neurotransmitter) nerve sites, which, at normal densities, function in critical ways to help re-initiate breathing following a sleep - related apnea or extended breathing pauses.

In animal models, exposure to cigarette smoke or nicotine during fetal development alters the expression of the nicotinic acetylcholine receptor in areas of the brainstem important for autonomic function, 28 alters the neuronal excitability of neurons in the nucleus tractus solitarius (a brainstem region important for sensory integration), 29 and alters fetal autonomic activity and medullary neurotransmitter receptors.30 In human infants, there are strong associations between nicotinic acetylcholine receptor and serotonin receptors in the brainstem during development.31 Prenatal exposure to tobacco smoke attenuates recovery from hypoxia in preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDS.

AChE inhibitors have also been given to Alzheimer's patients in an attempt to boost acetylcholine levels and improve cognitive function, she says — but her research suggests that the long - term effect may be the opposite of that intended.

Similar SH3 binding motifs exist in the formins, proteins that function in pattern formation in embryonic limbs of the mouse, and one subtype of the muscarinic acetylcholine receptor.

A Gain - of - Function Mutation in the α9 Nicotinic Acetylcholine Receptor Alters Medial Olivocochlear Efferent Short - Term Synaptic Plasticity

The rationale behind the project is that acetylcholine plays are role in cognitive functioning and that there is a subgroup of schizophrenia patients that have reduced density and M1 receptor binding in the hippocampus and dorsolateral prefrontal cortex that are referred to as «muscarinic receptor - deficit schizophrenia» or MRDS.

Yakel's research is directed toward understanding the role of the nicotinic acetylcholine receptor and brain function, as well as how dysfunction in this receptor leads to various neurodegenerative diseases and addiction.

Here's a tantalizing prospect, hinted at by a long - running thread of brain research: compounds that boost the function of certain acetylcholine circuits in the brain might also modify production of toxic beta - amyloid protein.

The yolk of an egg is an excellent source of choline, a precursor to acetylcholine, the neurotransmitter that helps to improve your focus and attention by regulating cognitive function.

To make matters worse, as you age, you make fewer of the chemicals your brain needs to function properly — including the signaling brain chemical acetylcholine, which helps support memory and cognition.

The nutrient DMAE works to maintain healthy levels of acetylcholine, an important neurotransmitter for cognitive function.

Brain Function — DMAE works by accelerating the brain's synthesis of the neurotransmitter acetylcholine, which in turn plays a key role in maximising mental ability as well as in preventing loss of memory in ageing adults.

Acetyl - L - Carnitine also promotes biosynthesis of acetylcholine, a key neurotransmitter for brain and nerve function.

This disease is caused by an inability of the certain nerve receptors (nicotinic acetylcholine receptors (AChRs) to function properly.