Further animal studies led to the FDA's change of heart.
He and his colleagues plan
further animal studies of the drug and hope to move on to safety trials in people.
The exact mechanisms must be probed in
further animal studies, Reid says, but eventually he hopes researchers will be able to use a patient's bacterial makeup as a biomarker for cancer screening or to develop probiotics for improving prognosis and treatment outcomes.
Further animal studies by Kipnis and others show that learning new tasks triggers a mild stress response within the brain, which prompts CD4 cells to rally to the meninges, the membranes that surround the brain.
Not exact matches
And earlier this year, a
study showed a neural link between generosity and happiness,
further cementing humans as fundamentally social
animals.
«It is my desire and my purpose to
further the education of the people of Texas and elsewhere in wildlife conservation, in the knowledge of the breeding and living habits of our wild creatures and in the relationship of wildlife to domesticated livestock on our ranches and farms; to afford students and others interested in wildlife betterment and propagation and in the raising of wildlife along with domesticated
animals a place for research and an opportunity for the
study thereof; and to develop scientifically methods of increasing the wildlife population of the state and nation for the benefit of future generations... who may not have the opportunity to know and appreciate our wildlife, as I have, unless methods of increasing and conserving our wildlife are scientifically developed.
So
far, all human
studies of oxytocin's role in social interaction show that we respond similarly to
animals.
Aquatic
animals were by
far the most commonly reported type of injury, accounting for two - thirds of
studies.
Further studies in
animal models and patients (with altered TRPM7 channel function) have been initiated, in order to evaluate the efficacy and safety of magnesium as a therapeutic for this disease.
«Chronic inflammation of the intestine is thought to be caused by abnormal interactions between gut microbes, intestinal epithelial cells and the immune system, but so
far it has been impossible to determine how each of these factors contribute to the development of intestinal bowel disease,» said Hyun Jung Kim, Ph.D., former Wyss Technology Development Fellow and first author on the
study, speaking about the limitations of conventional in vitro and
animal models of bacterial overgrowth and inflammation of the intestines.
In subsequent
studies the researchers plan to analyze
further relevant datasets in order to test different scenarios of the evolution of the earliest
animal phyla.
Last week, a research consortium posted the draft sequence of the naked mole rat's genome online;
further study may unlock the genetic clues to this unique
animal's survival abilities.
Inhibitory cell - based neuro - therapy is a new approach and has shown promise to date in early
animal studies, warranting
further development,» says Cory Nicholas, a co-first author.
«The
study provides
further evidence to explain why dinosaurs were one of the most successful groups of
animals to live on this planet.»
Nath's team is currently developing an
animal model of Nodding syndrome to
further study the disease and test potential therapies.
The biomedical device company CryoLife, Inc. is now using the researchers» design to build ring implants for
further studies in lab
animals, Karp says.
Because the researchers found that CTLA4Ig was effective in suppressing hepatitis in this
study, they suggest that CTLA4Ig should be among the therapeutic options investigated
further as a potential therapy for patients with severe acute hepatitis B. To this end, this
animal model is useful for virological and immunological analysis of HBV infection.
Professor Palombo said
studies in
animals and, eventually, humans are required to take this research
further.
Shettleworth calls the
study «provocative,» but insists that
further experiments with more
animals are needed before Santino's behavior can be interpreted as advance planning.
But others worry that the
study, if wrongly interpreted, could lead to
further restrictions on
animal research.
Although the trial first received the go - ahead in January last year, it was put on hold the following August by the US Food and Drug Administration, which demanded
further evidence that the treatment wouldn't cause cysts like those seen in some
animal studies.
Vertebrate evolution generally proceeds at
far less than a snail's pace, making
study of the process in living
animals difficult at best.
Griffin is now
studying other penguin species and four - legged
animals to
further explore the mechanics and energetics of walking.
Complex phenomena — which we have so
far only been able to
study in live
animals - can now be investigated in simple laboratory experiments using cultivated cells,» says postdoc Hans Christian Cederberg Helms from the Department of Pharmacy.
While the mouse
study does not prove a direct connection between Zika infection and microcephaly, Rossi said, it does underscore the urgent need for effective
animal models to
further study the course of disease and its transmission.
Complicating
study of the virus even
further, a lab
study found that an infected mosquito can pass the virus to nearby mosquitoes while they are feeding on an uninfected
animal.
The amazing variety of human faces —
far greater than that of most other
animals — is the result of evolutionary pressure to make each of us unique and easily recognizable, according to a new
study by University of California, Berkeley, scientists.
While the overall distribution of white sharks is very broad, ranging from Newfoundland to the British Virgin Islands and from the Grand Banks to the Gulf of Mexico as
far west as the Texas coast, 90 percent of the
animals recorded in this
study were found along the East Coast roughly between the Florida Keys and northern Caribbean Sea to Nova Scotia, Canada.
«The next stage would be to repeat the
study in primates, a more suitable
animal model where HIV infection induces disease, in order to
further demonstrate elimination of HIV - 1 DNA in latently infected T cells and other sanctuary sites for HIV - 1, including brain cells,» Dr. Khalili said.
Studying animals that show similar hemispheric biases for their own vocalization — like primates, sea lions and horses — could reveal important clues about how ancient language - processing mechanisms are, she adds: «Evolutionarily, this could go
far beyond primates to a common ancestor for all mammals.
Most
studies of
animal warning colors focus on how well they deter potential predators, but
far fewer have examined whether the same signals help their bearers avoid detection by parasites, prey, or competitors, the researchers say.
Our findings have confirmed that it is crucial to
study further the actual microbial environment within the
animal fur to confirm these associations.»
It turns out that these exotic sea critters — affectionately known to the researchers in the
study as «shrimp from Mars» — can see a kind of light that, as
far as we know, is not apparent to any other
animal on the planet.
Further studies showed that very similar genes controlled the process in
animal and human cells, and also helped piece together how the genes work together to keep the cell's recycling centers running.
This
study also increased the number of genetic markers scientist can use to
study the population biology of great white and related sharks, Stanhope said, by a thousandfold, from which they hope to
further expand knowledge of these fascinating
animals, many of which are in urgent need of conservation.
Model behavior So
far, there are only a few autism
studies in which the sex of
animals seems to make a difference, but that may be because scientists have only just begun to look.
A report published in March in the journal Trends in Genetics revealed that the lizardlike native of New Zealand has undergone the fastest rate of molecular evolution of any vertebrate
animal studied thus
far.
The authors of that
study reported that termite mounds are «hotspots» of plant growth and
animal activity that decreases the
farther one gets from the mound.
The
studies suggest that the viruses — one of which also widely circulates in
animals in Vietnam — could be involved in brain inflammation and paraplegia, but
further studies are needed to confirm a causative link.
Author of the
study Aldrich commented, «
Far too often, well - meaning,
animal - loving people fail to recognize the suffering of wild primates in captivity.
The results of this
study contribute to our understanding of how plants and
animals will respond to global climate change and highlight the need to slow and prevent
further warming.
This ability — termed maneuverability — has
far - reaching implications for
animal success and survival (1, 2) but is challenging to
study because it includes a wide range of distinct behaviors and is characterized by spontaneity.
In a
study published in the June 12 edition of Science, they detail how a new drug repaired damage to the colon, liver and bone marrow in
animal models — even going so
far as to save the lives of mice who otherwise would have died in a bone marrow transplantation model.
A Mexican national who went to school not
far from Xochimilco, she never thought much about the
animal and certainly never considered
studying it until she came to Germany.
Dr. Zhu said he believes the
study provides the scientific community with an important
animal model to
further investigate ARID1B's role in human brain disorders and will be a useful tool for therapeutic testing of potential treatments for autism, intellectual disability, and Coffin - Siris syndrome.
But without
further study in live
animals, «it's impossible to say» how important the webs are for fighting infection, cautions microbiologist Victor Nizet of the University of California, San Diego.
A new
study at the Smithsonian Tropical Research Institute (STRI) in Panama shows that lianas prevent canopy trees from producing fruit, with potentially
far - reaching consequences for other plants and
animals.
«Our
studies in
animals so
far suggest it doesn't have major side effects.»
«The results of our
study have huge implications for better understanding early sea turtle survival and behavior, which may ultimately lead to new and innovative ways to
further protect these imperiled
animals,» said Mansfield.
At a just - concluded archaeology meeting in Paris, and in a paper published online today in the Proceedings of the National Academy of Sciences, they draw upon
further studies at the site to argue that the
animal remains — which include the shells of 71 tortoises and the bones of at least three wild cattle — were consumed during a feast to commemorate the death and burial of the woman.