Sentences with phrase «further animal testing»

The researchers said further animal testing is needed to determine optimal dosage, dosing frequency and other factors.

The compound, already proven safe for humans, is undergoing further animal testing in preparation for possible clinical trials in cocaine addicts, the researchers say.

Not exact matches

Again, this isn't completely clear: most of the evidence so far comes from tests on animals, although there has been one proper randomised controlled trial, published in December, by KCL colleagues of Di Forti's.

Hingtgen's group is already testing how far their tumor - homing cells can migrate using larger animal models.

In subsequent studies the researchers plan to analyze further relevant datasets in order to test different scenarios of the evolution of the earliest animal phyla.

The unexpected idea has been tested only in cells and animals so far, but some scientists are already considering whether lowering oxygen levels might treat certain rare but deadly conditions.

Nath's team is currently developing an animal model of Nodding syndrome to further study the disease and test potential therapies.

Thus far, no genetically modified animals have thrived in the wild — unlike some of the GMO plants that have spread beyond test plots.

However, scientists say the tests may have exaggerated the impact by subjecting animals to doses of CO2 far higher than they would sense during careful gas disposal.

Two years later a coalition of green groups led by NRDC and including the International Fund for Animal Welfare (IFAW), the League for Coastal Protection, Cetacean Society International, and Ocean Futures Society upped the ante, asking the federal courts to also restrict testing of more intense, harmful and far ranging mid-frequency types of sonar off Southern California's coastline.

Except for houseflies, animal species tested with CR so far, including primates, rats, mice, spiders, Drosophila, C. elegans and rotifers, have shown lifespan extension.

The researchers plan to perform further tests on lab animals to assess the fake cells» long - term health effects before running clinical trials.

Venoms have been shown to fight cancer, kill bacteria, and even serve as potent painkillers — though many have only gone as far as animal tests.

This is the most efficient so - called «optogenetic switch» activated by red and far - red light that has been successfully designed and tested in animal cells — and it doesn't require the addition of sensing molecules from outside the cells.

Green says that the treatments may last longer in humans than in mice, but clinical trials will not begin before further testing in other animals.

This means that (1) animals are directly involved in an oxygen - regulating cycle or feedback loop that has previously been overlooked, and (2) we can directly test the idea (despite the uncertainties associated with looking so far back in time) by looking for a decrease in ocean oxygenation in conjunction with the spread of bioturbation.

Dr. Zhu said he believes the study provides the scientific community with an important animal model to further investigate ARID1B's role in human brain disorders and will be a useful tool for therapeutic testing of potential treatments for autism, intellectual disability, and Coffin - Siris syndrome.

A draft law that is now wending its way through the political system would put far - reaching limitations on animal testing that go well beyond those required by the European Union, and some wonder whether it is in compliance with the E.U. directive.

Looking further ahead the research will expand to include animal testing and then a series of clinical trials in humans.

After further testing, they discovered that the scent of a male — human or otherwise — actually acts like a painkiller by ramping up the animal's stress levels.

The protein, called glial cell - line derived neurotrophic factor (GDNF), was first isolated in 1993 and has so far only been tested in animals.

To ensure that the glial cell - to - neuron conversion method is not limited to rodent animals, Chen and his team further tested the method on cultured human glial cells.

So far, Dr Gross and his team have tested Turing Learning in robot swarms but the next step is to reveal the workings of some animal collectives such as schools of fish or colonies of bees.

Although further refinement and testing is needed, Dr. Burgess said the new techniques have the potential to speed the production of many different types of transgenic animal models that will shed new light on human development and disease.

As a result of a number of natural animal lineages with this mutation, myostatin knockout is by far the most examined and tested of all potential gene therapies.

Further discussions of REACH and alternative testing methods will be addressed at the 7th World Congress on Alternatives & Animal Use in the Life Sciences held in Rome, Italy, August 30 to September 3.

Even if glcosepane's low tissue burden in rats means that cleaving it will not have dramatic rejuvenating effects in these animals (which is a reasonable prediction, but might be happily disproven in the event), its high prevalence in aging and diabetic human collagen, and its implication in the complications of diabetes, will make the mere demonstration of a candidate's ability to cleave glucosepane crosslinks in vivo a sufficient proof - of - concept to spur further work to move it down the therapeutic pipeline into human testing.

It should be possible to work some of these issues out by further test - tube research and studies in animals.

«Our plan now is to further optimize and test these synthetic cells in larger animals, develop a skin patch delivery system for them, and ultimately test them in people with diabetes,» says principal investigator Zhen Gu.

Their hope is that drug candidates that get as far as animal testing and clinical trials will then be more likely to be safe and effective.

So far, we've seen gene silencing drugs tested in several different animal models of Huntington's disease, successfully delaying symptom onset or even reversing symptoms.

Far from replacing animal testing, computer simulation is leading to smarter experiments — and the need for more animals.

It is far from clear that thalidomide's terrible effects would have been detected even by today's animal testing.

However, the testing was only done on animals so far.

Further testing is being pursued After passing chronic and acute toxicity testing in animals, a pilot study was undertaken with HCV patients.

The Weston A. Price Foundation plans to do further testing of broth, and it encourages consumers to know their farmers and the living conditions under which poultry and animals are raised.

Surely Ri Ri's socially conscious make - up range is all about keeping product testing far away from animals, right?

The first round is based purely on appearance, followed by further sections such as job, family, view on testing on animals as well as other key factors.

While we're on the subject of frugality, it also boasts the best EPA fuel economy ratings, and in our rigorous testing (we drove like animals) used by far the least fuel.

To thwart pet owners from leaving behind waste, some apartment building managers have gone as far as testing abandoned feces to match DNA with resident pets and identify the offending animal's owner.

Before allowing the animals to progress further they must pass the AKC Good Citizen Test qualifications and Public Access tTest qualifications and Public Access testtest.

The mirror test is so far the only way that we can measure if an animal is self - aware.

Following the test results, the staff at Animal Care Unlimited, referred Skye to a nearby specialty hospital for further treatment.

Negative results may occur even when animals are infected depending on timing of sampling or excessive blood in stool, so an ill animal with negative test results may require further testing and care and should still be handled as though infectious.

Complicated problems that require further testing may involve your animal staying with us for the day.

The HACC, Inc wanted to take this proposition one step further and test this idea at a public Animal Shelter.

The problem is that the initiative appears to be limited to purebreds, though the crisis created by vicious animals extends far beyond those sacred breeds and the owners most likely to need such encouragement are least likely ever to hear of it.According to the AKC, the test will consist of 10 categories that will show the dog's acceptance of strange people and strange dogs and of being handled in routine ways, such as grooming or petting by unfamiliar people.

Rescue animals come with flea treatment, vaccines, spay / neuter surgeries, microchips, viral testing, and more — providing all these yourself would cost far more than any adoption fee.

These tests enable our veterinarians to further assess each animal's general health, further evaluate their heart and lungs, and also evaluate kidney and liver function prior to anesthesia.

Shallowford Animal Hospital is pleased to take their service one step further by offering ultrasound testing.