Sentences with phrase «further decreasing their ability»

We only included women aged 40 — 60 y that further decreases the ability to extrapolate our findings to the whole population.

This has even greater implications for children who have experienced trauma and may feel constantly threatened and unsafe, further decreasing their ability to access the parts of the brain that manage rational thought.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

The approach halts further necrosis and can save a baby's life, but it often leaves infants with insufficient intestine and puts them at risk for long - term complications, such as short bowel syndrome, which requires feeding support for life due to the intestines» decreased ability to absorb enough nutrients.

Guessing that the reduced ability to control force in patients with PD was related to decreased dopamine — which makes it harder to «recruit» neurons for a particular task — the researchers devised a brain stimulation experiment to further test their hypothesis.

The ability of our eyes to change shape to allow for near - focus or far - focus is high when we are young and decreases with age.

The required supplies (BOX 3) are minimal in cost — $ 0.26 per patient — but offer the ability to further decrease the use of inhalant agents and the maintenance fluid rate, thereby preventing use of hypotensive treatments and further reducing the clinic's overhead cost.

Books further augment his skills by providing passive abilities, which buff weapon durability or decrease the zombies» detection radius, for example.

In addition, the ability of biomass and oceans to take up some of the emitted CO2 is decreasing, which will further amplify the warming influence.

No surprise that this impacts our enthusiasm and ability to be at our best, making the job search even more difficult and further decreasing our chances of success.

This improvement in cognition generally would then be the basis for any improvements in behaviour (far transfer, ie, improvements in overall executive functioning ability lead to decreases in psychopathology).