Not exact matches
Beyond offering
further proof that single genes can have
dramatic influences on longevity, an idea that drew skepticism just a decade ago, the new finding may help scientists explain how severely reducing calorie intake extends life span in a variety of animals (SN: 11/25/00, p. 341: Low - cal diet may reduce cancer in monkeys).
Even if glcosepane's low tissue burden in rats means that cleaving it will not have
dramatic rejuvenating effects in these animals (which is a reasonable prediction, but might be happily disproven in the event), its high prevalence in aging and diabetic human collagen, and its implication in the complications of diabetes, will make the mere demonstration of a candidate's ability to cleave glucosepane crosslinks in vivo a sufficient
proof - of - concept to spur
further work to move it down the therapeutic pipeline into human testing.
Opening in theaters almost a year after it emotionally captivated audiences at Sundance, Quest is
further proof that the Steve James model of long - term filming commitments pays big
dramatic dividends.