«Through
further functional studies we found that myosin IIa is also required for activation of the main guardian of the genome — a tumor suppressor protein called p53.»
The method identifies gene sets that show evidence for positive selection in comparison with matched controls, and thus highlights genes for
further functional studies.
Not exact matches
«Taken together with previously established benefits of egg intake on HDL profiles, these findings
further support the notion that eggs serve as a
functional food to reduce cardiovascular disease risk in individuals with metabolic syndrome,» says Catherine Andersen, lead
study author and PhD candidate at the University of Connecticut.
In the wake of this lobbying, the provision calling for
further study of
functional ingredients was dropped from the Senate version of the bill.
To investigate
further, the team
studied mice lacking a
functional PER3 gene.
So
far,
studies in this field have mainly been based on
functional magnetic resonance imaging (fMRI).
«Our
study sets the stage for
further research to identify which additional cues could induce these neurons to fully mature and incorporate into
functional circuits, thereby allowing this approach to potentially be used in the clinic,» Berninger says.
Our new
study has shown that we can go even
further: from these co-mutations it is possible to uncover the protein's macrostructure, its fundamental structural and
functional units.»
«Most
studies that have so
far dealt with this question by means of
functional imaging have mostly examined only very small and heterogeneous samples, which clearly differ with regard to age, gender or duration of illness.
In a
further step, Matthias Fastenrath
studied the brain activity of 700 healthy participants via
functional imaging while they were were solving working memory tasks.
Further studies with neuropsychological evaluation will be needed to characterize the
functional consequences of these structural changes.»
The results are intriguing and call for
further work, says Thierry Boulinier, an immune ecologist at the
Functional and Evolutionary Ecology Center in Montpellier, France, who was not involved in the
study.
Barbey's group is
further studying how individual differences in
functional brain connectivity are shaped by learning and experience.
«This
study for the first time shows increased expression of IL - 33 in AMD and
further demonstrates a role for glia - derived IL - 33 in the accumulation of myeloid cells in the outer retina, loss of photoreceptors, and
functional impairment of the retina in preclinical models of retina stress,» the authors note.
«As
far as we know, this is one of the first
studies of dyslexia to examine differences in
functional connectivity across the whole brain, shedding light on the brain networks that crucially support the complex task of reading,» added Finn.
«As eliciting a highly diverse immune response may be favorable to providing protection against incredibly diverse HIV - 1 variants in global circulation,» the researchers conclude that their
study «supports
further investigations of the molecular and
functional characteristics of the virus - antibody interplay in superinfected individuals, as superinfection may provide insight to the development of a diverse Nab response with multiple epitope specificities.»
Further studies may address whether differentiation of these limbal - iPSCs to a non-related cell type provides suitably
functional cells, and therefore, if they represent an ideal source for therapeutic purposes throughout the body.
Further studies showed that Notch1 knockdown in NSCLC helps induce cell death (which inhibits tumor initiation and growth); this process is mediated by p53, and thus the effects of inhibiting Notch1 require
functional p53.
The
study of antigenic targets of naturally - acquired immunity is essential to identify and prioritize antigens for
further functional characterization.
Both reviewers consider that since the
functional studies were only tested in 2 basal and 2 luminal breast cancer cell lines, the sample set was too small, and testing additional cell lines for their dependency on MELK should
further strengthen the authors conclusions.
She has
furthered her
studies with Andrea Nakayama completing the Full Body Systems Comprehensive
Functional Nutrition Immersion.
Further studies on foods made with pulse flours may be of interest, given its potential as a
functional ingredient (59) and the expanding variety of products made with pulse flours now available, such as tortillas, pasta, and bakery products.
Studies have shown that even highly
functional low - income parents speak
far less to their children, on average, than affluent parents.