Sentences with phrase «further growth of any cells»

Success is best when the tumor is small; large cancers are surgically removed before the treatments and radiation is used to stop further growth of any cells missed in the surgery.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Most of the wireless industry is looking for new markets, as the number of cell phones now far exceeds the number of people in the United States and revenue growth is hard to find.

And it is the consensus of experts that such tariffs themselves are far from sufficient to result in widespread growth in the domestic solar cell and module manufacturing space.

Heretofore, this earth has witnessed the emergence of single - celled living organisms, the growth of multicelled plant organisms, the advent of animals with centralized nervous systems making self - directed activity possible, and the flowering of humanity with its far - flung culture.

In both cases individual members may exercise some dominance over others, in particular by altering the patterns guiding further growth and development, but the social coordination stems from basic patterns embodied in the genetic makeup of the plant cells and in the laws and traditions of human culture.

Lewis is now skimming through these genes to check their function; of those he's looked at so far, several are involved in growth and development, cell differentiation, cell death, and protecting against cancer.

Lo's team set out to find ways to further weaken the tumors, since the drug addiction response (which can range from a mere slow down of the cancer's growth rate to cancer cell death), can be used to improve clinical outcomes.

«In most cases we think the body's growth control mechanisms eventually stop the cells from proliferating further, but in occasional cases where additional mutations occur in the clump of cells, a tumour will eventually develop,» says Andrew Wilkie also of the University of Oxford, who supervised the work.

Then came a new step: They carefully extracted the fragile, immature eggs and some surrounding cells from the follicles, and allowed them to further mature on a special membrane in the presence of more growth - supporting proteins.

Such a drug would block only the androgen receptor in prostate cells, and so stop the chain of reactions leading to further tumour growth, says McCague.

While further research is needed to understand the effectiveness of H1.0 protein in preventing the spread of cancer growth, this research advances significantly the study of the mechanisms of cancer stem cells and the relatively new epigenetic approach to cancer research.

«You can see they are very active and affect the DNA in the tumor tremendously, causing lots of mutations that may further the cells» uncontrolled growth, says Alon Keinan, a computational biologist at Cornell University.

Further investigations could pave the way to a more complete understanding of the genetics and metabolomics of cell growth in yeast and the underlying mechanisms relevant to other settings in which cells face challenging conditions, such as cancer progression and the evolution of drug resistance.

Yet, more recent discoveries suggest a much more active role of endothelial cells during tumor growth than has been anticipated so far.

They have a burst of growth that increases the pool of cells waiting for the next mutation to push them even further.

Ralph Brinster, part of the team at the University of Pennsylvania in Philadelphia that first cultured sperm stem cells in the lab, has written that culturing stem cells from human sperm is not far off — humans and mice, like other mammals, he says, require similar growth factors.

On the other hand, genetic mutations that further promote the growth of intestinal stem cells are associated with uncontrolled organ regeneration and the development of colon cancer.

We further determined that T cells deficient in DGKζ exhibit greater control of murine pancreatic tumor growth as compared with T cells deficient in Cbl - b.

By stimulating the growth of new blood vessels, promoting anti-inflammatory effects, recruiting cells toward tissue regeneration and inhibiting further cell death, adult stem cells can restore some function to damaged or diseased heart muscle.

These abnormal cells — in the case of pulmonary hypertension, those that line the blood vessels leading to the lungs — release signals that stimulate the growth of small new blood vessels to feed the renegade cells, allowing further proliferation, and thickening of the vessel walls.

Six ovarian factors (BDNF, IGF - I, estradiol, GDNF, leptin and FGF2) were further studied based upon the expression of their receptors in oocytes and cumulus cells described above, as well as the availability of growth factor concentration information from previous animal model studies [1], [20], [21], [22], [23].

With each cell division the telomeres of most cells shorten and this progressive DNA loss triggers a growth arrest that prohibits the cell from dividing further.

«Our study also highlights that growth of normal cells and cancer cells is driven by different gene switches, suggesting that further work to find ways to control the activity of such disease - specific switches could lead to novel, highly specific approaches for therapeutic intervention», says Professor Jussi Taipale, who led the study.

Further studies showed that Notch1 knockdown in NSCLC helps induce cell death (which inhibits tumor initiation and growth); this process is mediated by p53, and thus the effects of inhibiting Notch1 require functional p53.

Further, white tea may be able to prevent the growth of new fat cells.

Cancer is said to be a disease of old age, that is because we are living longer, we are encountering more carcinogens which further mutate our DNA which can lead to uncontrolled cell growth.

Pure pomegranate seed oil may help breast cancer patients inhibit further growth of cancer cells.

Start with a «fasting mimicking» diet, like our 26 - day detox, know that you're giving yourself an amazing health reboot — with some loss of fat stores being an inevitable result, some increase in human growth hormone and stem cells — and congratulate yourself on your wins, as you think about taking it a step further, potentially, later.

In summary, perhaps through glucose «starvation» of tumour cells and by reducing the effect of direct insulin - related actions on cell growth, ketogenic diets show promise as an aid in at least some kind of cancer therapy and is deserving of further and deeper investigation — certainly the evidence justifies setting up clinical trials.

Here's a quote: «Lactoferrin: Lactoferrin found in foods such as yogurt and kefir will stimulate new bone growth while preventing further breakdown of existing bone tissue, lactoferrin enhances both the growth and the activity of osteoblasts (the cells that build bone), and reduces the rate of bone cell death by 50 to 70 percent and decreases the development of osteoclasts, the cells responsible for breaking down bone.»

The exciting finding by University of Washington researchers provides further proof of the powerful effect of artemisinin on cancer and the powerful effect of combining naturally - occurring herbals with other essentials, such as iron, to combat cancer cell growth.

So far this year, American Veterinarian ® has reported on immunotherapies that may slow growth or even shrink gliomas in dogs and humans, a liquid biopsy assessment tool to detect tumor cell mutation, and a shared study between the American Kennel Club Canine Health Foundation and the V Foundation for Cancer Research on the treatment of bladder cancer.

Installations of solar cells are doubling every two years, and the annual growth in wind generating capacity is not far behind.

Sales of solar cells are doubling every two years, and the annual growth in wind generating capacity is not far behind.

He hates it so much that he further compares its «monstrous growth» to a hypertrophic, diseased organ that «grows to an abnormal size because of the uncontrolled growth of the cells that constitute it.»