«However,
further mechanistic studies are required to investigate whether irisin could act as a protective factor for the development of cardiovascular disease and age - related disorders.
This 3D proteomics brain data can be integrated with parallel 3D transcriptomic studies to possibly provide insights to interesting targets for either therapeutic intervention or
further mechanistic studies.
There is a clear need for
further mechanistic studies to explore the role of PREX2 and mutations of PREX2 in cancer.
Not exact matches
They go on to say that «since no single broadly neutralizing antibody combines the entire range of
mechanistic features anticipated to support in vivo efficacy, our
study adds
further evidence that combinations of such antibodies need to be considered for human application.»
So
far, «genome - wide association
studies» have identified variant DNA sequences showing statistical association with these and other complex diseases, but demonstrating a
mechanistic role for these variants has proven elusive.
In this way, in - depth immunological monitoring, genetic and proteomic analyses, and biomarker discovery from patient samples guides
further laboratory investigation, where
mechanistic studies can be designed and animal modeling performed.
Further, the HPCs derived here are immunologically well - defined, allowing
mechanistic studies.