Sentences with phrase «future clinical application»

(3) Future clinical application of human germline genome editing should not proceed unless, at a minimum, there is (a) a compelling medical rationale, (b) an evidence base that supports its clinical use, (c) an ethical justification, and (d) a transparent public process to solicit and incorporate stakeholder input.

The work on stem cell isolation strategies for future clinical application was recognized with a Medical Technology Innovation award and the Overall Grand Prix Award at the Engineer Technology and Innovation Awards in 2010.

Further, they agreed that before any future clinical application of germline genome editing takes place, there should be:

For future clinical applications, the pajamas will only emit their blue light inward, directly onto the child's skin.

Sunday, September 25 2:15 - 3:00 pm — The godfather of iPSCs, Nobel Prize - winner Shinya Yamanaka presents the opening keynote address on recent progress made in iPSC research and future clinical applications of the technology.

(2) Currently, there is no reason to prohibit in vitro germline genome editing on human embryos and gametes, with appropriate oversight and consent from donors, to facilitate research on the possible future clinical applications of gene editing.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Crucial research breakthroughs often lack direct clinical applications themselves but are essential for future discoveries with direct applications.

As such, it provides a means of moving organoids from basic research to actual pharmaceutical and clinical applications in the future.

In future studies, the researchers will characterize the interplay between the virus and host throughout evolution and continue to seek improved vectors for clinical applications.

In future work, the Eischen laboratory aims to further understand the role of lncRNAs in ovarian cancer, and potentially translate their findings into clinical applications to reduce ovarian cancer metastasis.

«The use of a mouse tumor - derived matrix would limit any future applications of these organoid technologies in humans, and this work opens the door to research directed specifically for clinical applications,» noted Asma Nusrat, study co-author and the Aldred Scott Warthin Professor and Director of Experimental Pathology in the University of Michigan's School of Medicine.

In future studies, Sulchek and his team plan to test this approach and scale up the technology with clinical applications in mind.

This would be a major breakthrough in the management of DCIS and although this research is not ready for clinical application yet it shows great promise for the future.»

Future work will include higher multiplexing and application in clinical settings.

We will also cover the varied applications for which organoids could be utilized, and investigate what the future could hold for organoids in research and clinical translation.

«If future clinical studies demonstrate that this strategy is effective, we hope our work will lead to development of new, low - cost atopic dermatitis therapies that do not require daily application,» Myles, an NIAID researcher, said in an institute news release.

A planned future use for this test is its application to detect the presence of hemangiosarcoma in dogs at risk before the tumor poses a clinical hazard.

Symetis is also developing the ACURATE neo / AS ** next generation valve system, currently in a clinical trial intended to serve as the basis for a future CE mark application.

A well - written resume sample for Clinical Applications Specialist mentions duties such as answering to customer inquiries, organizing training sessions, making suggestions on future products and services, producing reports, and providing troubleshooting.

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Future research focused on application in clinical settings might usefully address the impact supplement and evaluate clinical cutoffs for psychiatric caseness.

Applications for future research and clinical assessment will be discussed.