Most likely,
the future of oncology will not rest on a single therapy but a precise combination of targeted drugs.
Not exact matches
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and
future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability
of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect
of lowering prices or reducing the number
of insured patients; the possibility
of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels
of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology /
oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's
future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Through this arrangement, Celgene obtained rights
of first refusal on the first three
oncology products Triphase advances to clinical proof -
of - concept, plus a right
of first negotiation on three more
future oncology products which may be acquired by Triphase.
If Novartis can get clinical trial success to translate into commercial success, it would bode extremely well for Gilead's
future as a leader
of this exciting new
oncology space.
«This study's results can have practice changing implications on how
future prostate cancer trials are designed in terms
of identifying the men for these studies who are at high risk for early death due to ineffective initial treatment for their prostate cancer,» stated Anthony Victor D'Amico, MD, PhD, chief, Genitourinary Radiation
Oncology, Brigham and Women's Hospital and senior author
of the study.
«
Future comparative
oncology studies, optimizing the delivery
of PMed strategies, may aid cancer drug development.»
«Overall the turnaround for sample analyses fit a relevant clinical window for
future comparative
oncology trials to model human PMed advancements,» said Dr. William Hendricks, a TGen Staff Scientist and another author
of the study.
«This study forms the basis for
future research in patients with breast cancer and offers hope for targeted therapy for patients with aggressive triple - negative inflammatory breast cancer,» said lead researcher Mateusz Opyrchal, M.D., Ph.D., Assistant Professor
of Oncology at RPCI.
Future studies are planned by Chang and other School
of Medicine researchers — including senior author Kenneth R. Carson, MD, PhD, an assistant professor
of oncology, and Graham Colditz, MD, DrPH, a cancer expert who also is associate director
of prevention and control at Siteman Cancer Center at Washington University School
of Medicine and Barnes - Jewish Hospital.
Tryfonidis et al. discuss perspectives and
future directions for the management
of locally advanced breast cancer in Nature Reviews Clinical
Oncology, and they see a need for not only standardizing treatment for this disease, but also for developing new therapies that could substantially improve outcome.
«Identification
of these variations has helped the family to better understand why their children developed cancer and to plan for the
future,» said co-author Kim Nichols, M.D., a member
of the St. Jude
Oncology department and director
of the St. Jude Cancer Predisposition Division.
«We urgently need markers to predict which therapies are going to be effective and which will not be effective in individual patients with advanced prostate cancer,» said lead study author Emmanuel Antonarakis, MD, an assistant professor
of oncology and urology at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins in Baltimore, Md. «AR - V7 testing may be extremely valuable in guiding treatment decisions for men with hormone - resistant disease in the near
future.»
As one
of the finest pediatric hematology -
oncology fellowship programs in the nation, our centers are training fellows to obtain outstanding clinical and laboratory research knowledge, paving the
future of pediatric cancer and blood disorder care.
His team will drive the discovery and development
of compounds to support Moderna's existing and
future research partnerships, as well as its internal efforts in rare diseases and
oncology.
Clinical Trials Research and Billing First in Human / Early Phase PET in
Oncology Case - Based Dose Reduction in Pediatric Nuclear Medicine: Practical and Necessary Radioiodine Therapy for Hyperthyroidism: The State
of the Art Spondylodiscitis: Role
of Imaging for Diagnosis and Monitoring Treatment Response Current Status and
Future Prospects: PET and SPECT Instrumentation Alternative Payment Models and Value - Based Health Care: Nuts and Bolts Maximal Tolerated Activity
of Radioactive Iodine for Metastatic Thyroid Cancer Teaching Old Radiopharmaceuticals New Tricks Intraoperative Detection Devices and Probes Molecular Imaging
of Lung Inflammation Standardization
of Advanced PET / SPECT Data Acquisition and Analysis Thyroid Cancer Management: Novel Therapeutics and Management Options Targeting Radionuclide Therapy in Various Non-Malignant Arthritic Conditions Using Radiosynoviorthesis (RSO) Are You Prepared for a Radiation Accident?
NJTV - New Pancreatic Study May Offer Hope for the
Future - November 17, 2011 CINJ Deputy Director Dr. Edmund Lattime and Co-Director
of CINJ's Gastrointestinal - Hepatobiliary
Oncology Program Dr. Elizabeth Poplin discuss early results to a unique clinical trial that uses vaccine therapy to target pancreatic cancer.
The theme
of this year's meeting is «Expanding horizons in Neurosciences: New approaches to Brain Activation», which will provide an international platform for discussion and sharing
of novel ideas for present and
future expansions in various fields
of neurology such as Neuroimmunology, Neurological disorders, Neuro
Oncology, Neuroimaging, Cognitive neuroscience and expertise meeting.
Archives
of Dermatological Research, March 2010, pages 71 - 83; Skin Pharmacology and Physiology, September 2009, pages 299 - 304; Skin Research and Technology, August 2009, pages 338 - 345; Dermatologic Surgery, July 2009, pages 1,057 - 1,065; Experimental Dermatology, June 2009, pages 522 - 526; Clinics in Dermatology, November - December 2008, pages 614 - 626; Skin Therapy Letter, September 2008, pages 5 - 9; Journal
of Drugs in Dermatology, July 2008, pages S7 - S12; Food and Chemical Toxicology, April 2008, pages 1,298 - 1,307; Journal
of Toxicology and Environmental Health, Volume 72, pages 796 - 806;
Future Oncology, December 2008, pages 841 - 856; Journal
of Pathology, January 2007, 241 - 251; Journal
of Radiation Research, December 2004, pages 491 - 495; British Journal
of Dermatology, October 2003, page 681; and Journal
of Dermatological Science, volume 31, 2003, pages 193 - 201; and Journal
of Investigative Dermatology, November 2003, pages 1,163 - 1,167; and January 2002, pages 117 - 125.
The PCOP is integrally involved in educating and training the veterinary
oncology team
of the
future.
He is currently working to develop the WCVM's human and technological resources in the areas
of veterinary
oncology and food safety and security — two areas that the college is focusing on for the
future.
If you're interested in being one
of these minds, working towards
future advances in
oncology, talk to us at Hays.