Sentences with phrase «future studies of disease»
Studying healthy individuals gave the researchers a baseline for future studies of disease - causing mutations.
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«Future studies need to determine the health effects of these cocoas in models of human disease and to evaluate the consumer acceptability of the cocoas as part of a chocolate product.»
Therefore, future birth cohort studies examining the incidence of atopic disease need to directly compare infants fed hydrolyzed (including both partially and extensively hydrolyzed formulas) and nonhydrolyzed formulas to exclusively breast - fed infants for a prolonged period.
«Future studies will not only seek to further map the function of AIM2 in infectious diseases, but also to track its role in other disorders, including cancer,» Man said.
«The study results elucidate the molecular mechanisms underlying disease progression in multiple sclerosis models, providing a basis for future clinical trials to determine safety and efficacy of these chemical agents in humans with demyelinating disorders,» says Patrizia Casaccia, MD, PhD, Professor of Neuroscience, Genetics and Genomic Sciences at Mount Sinai and senior author of the study.
«Study finds recurrent hypertensive disease of pregnancy associated with early mortality: Pregnancy provides a window to future health.»
This work helps us understand how medical male circumcision reduces HIV - infection in men and points towards novel interventions to decrease HIV risk in the future,» says Rupert Kaul, an infectious disease physician and the study's senior immunologist and a Professor at the University of Toronto.
«Our study shows simply adding one of our available cardiac imaging resources may more accurately predict a patient's risk or diagnose their disease, also giving us an opportunity to prevent them from experiencing a future cardiac event and possibly save more lives from the burdens of cardiovascular diseases.»
Therefore, in our opinion, they could be used in the future not only to improve the sugar metabolism but also to treat non-alcoholic fatty liver disease ***,» adds the lead author of the study, Christian Baumeier from DIfE.
The studies not only point to the future possibility of specific microRNAs as a treatment for colorectal cancer, but also to the importance of external metabolic events conducted outside the cancer cell in the progression of the disease — factors that could someday be targeted to help slow metastasis, or even block it entirely.
«This study convincingly shows that mild trauma has a role in increasing the risk of dementia and sheds light on the more complex relationship between medical and psychiatric diseases with TBI in the development of the future risk of dementias.
Both of the advantages point toward a possibility of using this new method for regenerative therapies and for creating models of rare diseases for future studies and individualized health care.
«These results enable future studies in Alzheimer's and other disease models and highlight the importance of basic research which precedes drug - discovery,» says Jaan - Olle Andressoo.
«This study shines a light on the pathogenesis of inflammatory bowel disease and offers a positive impact on its future clinical management,» says Liu.
The study also shows that metabolic strategies based on diet are sufficient to restore correct heart function, opening the possibility of future treatments for patients with this disease.
Carson and his colleagues plan future studies involving PET imaging of synapses to research epilepsy and other brain disorders, including Alzheimer's disease, schizophrenia, depression, and Parkinson's disease.
«It has shown that the value of sequencing a few thousand individuals is high for highly penetrant, rare diseases, but that for complex traits and diseases much larger sample sizes will be required in future studies.
The findings will likely guide future studies not only on the potential of nanodiamonds in drug delivery but also on fighting bacteria and treating viral diseases.
In future studies, the team plans to use the model to better understand how microbes, host factors and inflammatory markers interact to produce the hallmarks of inflammatory disease in the intestine.
«Future studies are necessary to determine the incidence of positive xenodiagnostic results for B. burgdorferi after antibiotic treatment, if these results represent viable organisms or remnants of infection, and whether these results can be related to ongoing symptoms in patients after therapy for Lyme disease,» they write.
«Our study reveals an explanation how nicotine contributes to induction of inflammation and in doing so shows new possibilities for future therapies to treat tobacco - related diseases which each year lead to premature deaths of several million people worldwide,» said Constantin Urban, a researcher involved in the work from the Umeå Centre for Microbial Research in Sweden.
An analysis of diagnostic test results from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial — in which patients with stable chest pain were randomized to either anatomic or functional testing as an initial diagnostic strategy — showed that the presence and extent of coronary artery disease detected by CT angiography better predicted the risk for future cardiac events than did measures of exercise tolerance or restricted blood flow to the heart muscle.
Our hope is that this and other similar studies can increase the possibilities of personalising treatments that slow down the disease in the future,» says Oskar Hansson, reader at Lund University and consultant at Skåne University Hospital.
In a comprehensive and complex molecular study of blood samples from Ebola patients in Sierra Leone, published in Cell Host and Microbe, a scientific team led by the University of Wisconsin - Madison has identified signatures of Ebola virus disease that may aid in future treatment efforts.
«This embryo gene correction method — if proven safe — can potentially be used to prevent transmission of genetic disease to future generations,» says study co-author Paula Amato.
From cholera to bird flu, researchers are studying how diseases spread at such events, in the hopes of preventing a future pandemic.
The study shows that patients suffering from RBD have a risk of developing Parkinson's disease or dementia in the future, because they already suffer from a lack of dopamine in the brain.
«This study highlights the importance of concussion prevention, long - term follow - up of those with concussion, and the need for future studies to investigate if there are other risk factors for Parkinson's disease that can be modified after someone has a concussion,» said lead study author Raquel C. Gardner, MD, of the University of California, San Francisco, the San Francisco Veterans Affairs Medical Center, and a member of the American Academy of Neurology.
Additionally, since ribosomal RNA has been shown to have specified controlled of cellular fate, this study provides a theoretical basis for disease therapy and neuroscience research and may lead to future advances in treating degenerative diseases or even brain cancers.
As many of these diseases have no effective treatment, future studies examining the role of glucose in regulating neutrophils and inflammation are critical.»
«The distinct neural markers associated with cognitive performance and GWI revealed in our study can be useful for future research to objectively measure the efficacy of treatments for GWI as well as other brain disorders related to the same neurotransmitter system, like Alzheimer's disease.»
By studying how research funding is allocated relative to the global burden of disease, and assessing the outputs and impact of research, the resulting data will be used to better inform future investment decisions.
«In the future we hope to apply this strategy to target other disease - causing RNAs, which range from incurable cancers to important viral pathogens such as Zika and Ebola,» added Research Associate Sai Pradeep Velagapudi, the first author of the study and a member of the Disney lab.
«The induced pluripotent stem cells we used in this study proved to be extremely useful in disease modelling, and they could offer an excellent platform for drug discovery and testing new therapeutic targets for Alzheimer's disease in the future,» says Early Stage Researcher Minna Oksanen, the lead author of the study.
«It's not yet clear whether or how GSK3 might be a target for future therapies for B cell - related diseases, but this research opens a lot of doors for further studies,» Rickert said.
Our findings clarify the disease's distinctive genetic signature, which should, in the future, help improve clinical trials, and lead to more targeted treatments,» said the study's lead author, Dr Jose Bras (UCL Institute of Neurology and Alzheimer's Society senior research fellow).
Whether or not future research supports the idea that the disease is transmissible, the study is «good for appreciating the potential role of IAPP in diabetes.»
«It's well established that psoriasis is associated with an increased risk for other comorbidities like chronic kidney disease, diabetes, and cardiovascular disease, but we don't yet understand how the severity of psoriasis impacts future risk of major health problems,» said the study's senior author Joel M. Gelfand, MD MSCE, a professor of Dermatology and Epidemiology at Penn..
Future work will focus on identifying cellular targets of ampulexins, and potentially generating a useful animal model for the study of Parkinson's disease treatments.
Future studies will focus on developing biomarkers capable of making early predictions on whether patients will develop a severe form of the disease.
- In a study with potentially major implications for the future treatment of autoimmunity and related conditions, scientists from the Perelman School of Medicine at the University of Pennsylvania have found a way to remove the subset of antibody - making cells that cause an autoimmune disease, without harming the rest of the immune system.
Future studies to better define the relationship between MSSA colonization and subsequent infection will help to clarify the importance of such interventions for preventing MSSA disease,» the study concludes.
Brain imaging using radioactive dye can detect early evidence of Alzheimer's disease that may predict future cognitive decline among adults with mild or no cognitive impairment, according to a 36 - month follow - up study led by Duke Medicine.
«When combined with existing knowledge, this study provides a new roadmap for future studies to identify the underlying causes of chronic kidney disease.
Using a biomaterial matrix of porous silk, the new, scalable system is capable of producing platelets for future clinical use and also provides a laboratory tissue system to advance study of blood platelet diseases.
Using a biomaterial matrix of porous silk, the new system is capable of producing platelets for future clinical use and also provides a laboratory tissue system to advance study of blood platelet diseases.
Dr. Budoff and Rine Nakanishi, MD, PhD, presented these findings at ACC.14, the annual scientific session of the American College of Cardiology in March, along with other researchers whose studies also found coronary artery calcium screening accurately predicted the risk of future heart disease.
In future studies, it will be important to measure the biomarker at several time points to determine whether levels of the biomarker increase as the disease progresses, Apte said.
The effectiveness of the concomitant approach demonstrated in this definitive study also indicates the importance of future clinical studies that seek greater clinical benefit through the study of multi-targeted approaches in earlier disease settings.»
The data yielded in this study will contribute to future studies of marine mammal diseases, conservation and evolution.