Sentences with phrase «future therapeutic target»
«AIM2 may be a future therapeutic target to regulate altered microbiota and dysregulated inflammation in the GI system,» said Dr. Zaki.
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Moreover, this pathway, specifically GARP, may be a potential future therapeutic target for treatment.
Bromodomains have long been a target of cancer therapuetic development, and the YEATS domain may now provide a new avenue for the development of future therapeutic targets.
Not exact matches
This work presents future targets for therapeutic interventions but requires significant work.»
«The study suggests certain gut microbiota, including Ruminococcus and Blautia, may be promising targets for future therapeutic strategies to treat metabolic disorders,» Professor Morris said.
The role of Apelin and Elabela in establishing the circulatory system makes them potential targets in future development of therapeutic applications for illnesses ranging from the various cancers, and cardiovascular diseases, to even metabolic diseases such as diabetes.
This can teach us which factors play a role in infection and those could be therapeutic targets in the future.»
«The induced pluripotent stem cells we used in this study proved to be extremely useful in disease modelling, and they could offer an excellent platform for drug discovery and testing new therapeutic targets for Alzheimer's disease in the future,» says Early Stage Researcher Minna Oksanen, the lead author of the study.
Our findings suggest that soluble Cd14 could be an interesting new therapeutic target for future clinical research.»
«Future studies on how PAF / PAFR signaling controls UCP1 levels through beta3 - AR production in the BAT of animals and humans may reveal new therapeutic targets to treat metabolic disorders associated with obesity,» said Junko Sugatani, Ph.D., a researcher involved in the work from the Department of Pharmaco - Biochemistry at the School of Pharmaceutical Sciences at the University of Shizuoka in Shizuoka, Japan.
Dr. Kirino says that «further studies to understand how SHOT - RNAs promote cell proliferation may lead to the use of SHOT - RNAs as potential target candidates for future therapeutic applications in breast and prostate cancers.»
In the future, my research could lead to the design of a new therapeutic strategy targeting BIN1.
Future investigations on the postsynaptic role of p - tau will be necessary to understand its toxic effects and provide insights into new therapeutic targets for maintaining spine integrity, highlighting the importance of tau toxicity as well as the impact of sex on tau - pathology.
The work provides insights into the future use of TNFR2 as a therapeutic target.
Third, the tumour phenotype of mice with genetic deletion of Tie2 in pericytes warrants some careful reconsideration of the concepts of therapeutic angiopoietin targeting to interfere with tumour angiogenesis and for the future design of anti-angiogenic combination therapies.
It could be suggested that Cyclin D1 protein may be a valuable prognostic marker in IDC and can be targeted in the future therapeutic approaches.
These proteins, if their roles in neuroprotection in the retina are fully established in the future by more comprehensive studies, may present novel therapeutic targets in treating retinal disorders including glaucomatous conditions.»
Given DAXX's putative regulatory role in autophagy, future studies may consider DAXX as a candidate marker and therapeutic target for prostate cancer.
«We believe the use of this index in future studies may help identify novel therapeutic targets against cancer,» Dr. Noushmehr said.
Therefore, the identification of cellular and molecular mechanisms underlying neuron - astrocyte communication will help to a better understanding of the mechanisms of brain phsyiology as well as to appropriately identify cellular targets to direct therapeutic approaches for the future treatment of several brain diseases.
«Those genes may become therapeutic targets or biomarkers that could allow us to individualize treatment in the future,» he said.
Highlight potential future therapies or therapeutic targets that are likely to be important in lymphoid malignancies.