Not exact matches
Since
gabapentin's release in 1993, there have been no human laboratory
studies done on the drug, Vickers Smith said.
Vickers Smith and other researchers authored a paper recently published in Psychology of Addictive Behaviors that explores recreational
gabapentin use by a cohort of
study participants in Appalachian Kentucky.
But they highlight the need for further research — including
studies to determine exactly how
gabapentin works to prevent nausea and vomiting.
Experience showing that
gabapentin can reduce chemotherapy - related nausea led to its being
studied for prevention of nausea and vomiting.
They point to the need for further
studies to compare
gabapentin to more traditional antiemetic drugs, as well as to understand «the actual mechanism by which
gabapentin preempts nausea and vomiting.»
The new analysis, including the largest group of
studies to date, suggests that
gabapentin has a «significant role... not only for alleviating postoperative pain, but also for preventing PONV,» Dr. Grant and coauthors conclude.
Meta - analysis of these primary outcome
studies showed reduced rates of nausea and vomiting for patients receiving
gabapentin before surgery.
In 3
studies comparing
gabapentin to placebo,
gabapentin showed no significant improvement of pain; and in the 3
studies comparing pregabalin to other analgesics, pregabalin actually fared worse in pain relief.
However, some
studies have shown that low doses can be used safely over the long - term and may even slow the progression of chronic kidney disease in cats.3 Other medications like buprenorphine, tramadol, amantidine,
gabapentin, and corticosteroids (e.g., prednisolone) have all been used to improve patient comfort in cats with arthritis.
One
study found that with the introduction of
gabapentin, the affected cat displayed a decrease in pain - associated behaviors including aggression, avoiding human interaction, and loss of appetite.
Gabapentin may play a role in chronic pain management in pets; however further research and
studies need to be done on efficacy and safety.
Two
studies, both published in the last few weeks, examined the potential of a human drug called
gabapentin to address the fear, anxiety and stress of cats in both those situations.
The first article, published in the Sept. 2017 issue of Advances in Small Animal Medicine and Surgery, reported on a double - blind, placebo - controlled
study looking at the ability of
gabapentin to reduce the stress scores of trapped community cats.
GaPP: a pilot randomised controlled trial of the efficacy of action of
gabapentin for the management of chronic pelvic pain in women:
study protocol