Recent studies have found elevated levels of this protein in post-mortem brain samples of patients with MS.. In this latest work, investigators compared the frequencies of «more active» and «less active» variants of the DNA sequences that control expression of
the galanin gene between healthy controls and MS patients.
«We hope that our findings will foster development of a personalized strategy for the prevention and treatment of multiple sclerosis, one that takes into account the gender - specific contribution of
galanin gene variants to susceptibility and disease progression,» said Dr. Victoria Lioudyno, lead author of the study.
Not exact matches
The researchers attached these entry keys to PNAs designed to shut down expression of a test
gene — the
galanin receptor
gene, which binds a protein,
galanin, that helps regulate everything from pain perception to food intake.