These experiments were essential to understanding the effect of
gemcitabine on cell cycle and the effective scheduling of checkpoint inhibitor for maximal malignant cell kill.
Not exact matches
Findings were presented at the WCLC are based
on the updated results of 12 lung cancer patients enrolled in the clinical trial with pembro and irinotecan or
gemcitabine with or without vinorelbine or docetaxel.
While testing the effect of many normal, non-cancerous, human cells
on the sensitivity of cancer cells to chemotherapy, they found a specific sample of normal human skin cells that rendered pancreatic cancer cells resistant to
gemcitabine.
Gemcitabine is used
on bladder, pancreas and ovary cancer, whilst DON has been tested in clinical trials.
Based
on results from this and previous studies, pemetrexed and
gemcitabine were included in a St. Jude - led multicenter clinical trial of children and adolescents newly diagnosed with medulloblastoma.
In a study appearing in the May 3 issue of JAMA, Pascal Hammel, M.D., of Beaujon Hospital, Clichy, France and colleagues assessed whether chemoradiotherapy improves overall survival of patients with locally advanced pancreatic cancer controlled after 4 months of
gemcitabine - based induction chemotherapy, and assessed the effect of erlotinib
on survival.
Influence of
gemcitabine chemotherapy
on the microbiota of pancreatic cancer xenografted mice.