Sentences with phrase «gen sequencing»

Austin, TX About Blog Genohub is the easiest and most reliable way to find and order next - gen sequencing services.

Various instrument platforms: RT - PCR, semiconductor and next gen sequencing, capillary electrophoresis, benchtop automation.

This will include robotic DNA extraction, genome - wide mapping with high density gene chips (querying 175,000 DNA markers), and next - gen sequencing of the entire genome of an affected dog (interrogating every letter of the 2.4 billion letter genetic code).

All of those tests, in the next two years, will transition from Sanger (classical) sequencing to next - gen sequencing.

With next - gen sequencing you are sequencing, 10, 50, or 100 or more genes together,» said Dr. Smith.

I'll be attending the coveted Marco Island meeting early next month (February 4 - 8), where I'll present a poster on my evaluations of short read aligners for next - gen sequencing data.

Some fellow NGS bloggers have covered some important developments in the field of next - gen sequencing.

Conceptually, SNVs should be the easiest things to find in next - gen sequencing data.

Taken together, these results support the utility of VarScan for variant detection in next - gen sequencing, and demonstrate the feasibility of large - scale mutational profiling by deep resequencing of pooled samples.

My primary research interest is the application of next - gen sequencing to uncover the genetic basis of rare disorders and pediatric cancers.

Yet those who produce next - gen sequencing data are rapidly adopting this universal short read data format as the de facto standard.

It's been an interesting year for the field of genomics as next - gen sequencing technologies continue to emerge, evolve, and in some cases, fade to obscurity.

Next - gen sequencing technologies have introduced two paradigm shifts for genomic medicine.

You may know me as the author of MassGenomics, a blog about next - gen sequencing, genetics, and genomics that I ran 2008 - 2018.

With longer (> 50 bp) fragment - end reads and / or paired - end libraries, it's possible to detect small insertion / deletion variants (indels) in next - gen sequencing data.

The capabilities of next - gen sequencing would continue to surprise us: the Trace Archive couldn't hold them, and even the Short Read Archive ultimately failed.

The wide availability of high - throughput sequencing and ever - more robust and user - friendly analysis tools put the power of next - gen sequencing in the hands of the entire research community.

The ultimate goal is to translate discoveries enabled by next - gen sequencing into medically actionable information.

Though not required, experience in bioinformatics, next - gen sequencing, FACS, and ELISA is considered a plus.

Notably, due to the high instrument cost and staggering computational requirements, most next - gen sequencing took place at a handful of large - scale sequencing centers around the world.

More importantly, it became accessible: companies and core labs began to offer next - gen sequencing as a service.

We published the first complete genome of a tumor in 2008 and have applied next - gen sequencing technologies to breast cancer, glioblastoma, ovarian cancer, leukemia, and other cancers.

This study also represents one of the largest surveys of breast cancer by next - gen sequencing, certainly by whole - genome sequencing.

Seventy - seven cases from two neoadjuvant aromatase inhibitor clinical trials underwent next - gen sequencing (46 whole - genome, 31 exome).

Enrichment for such regions, coupled with the growing throughput of next - gen sequencing, yields sufficient coverage to identify small sequence variants (SNVs and indels) with great accuracy.

A clinical trial of AI therapy response paired with next - gen sequencing offers the opportunity to profile the genetic alterations of AI - sensitive and AI - resistant tumors.

In the fields of next - gen sequencing and genomics, this problem is getting worse.

Next - gen sequencing is particularly useful for analyzing highly fragmented DNA, adds Eske Willerslev, a geneticist at the University of Copenhagen's Natural History Museum of Denmark, because it can capture the sequences of exceedingly short stretches of nucleotides.

I started MassGenomics in 2008 out of a desire to share my experiences with next - gen sequencing, which was still a relatively new technology.

In my last post, I wrote about the return of results from next - gen sequencing, specifically a recent paper in AJHG about secondary findings in ~ 6500 ESP exomes.

In fairness, some of those who work in the field of next - gen sequencing, even to tackle genetic diseases, do not have knowledge of (or even access to) laboratory techniques that could functionally validate their findings.

Using a combination of next - gen sequencing and a third - generation, single - molecule sequencer from Helicos Biosciences that can sequence DNA directly without the need for an amplification step, his group sequenced the 700,000 - year - old horse DNA that still holds the record as the oldest genome yet sequenced.4 «This type of technology will be the future,» he says.

This is a slight exaggeration, but with the power of next - gen sequencing and human genetics, it's still plausible.

We should move quickly to collect the information necessary for well - guided decision making, because one thing is clear: Next - gen sequencing will soon be a routine part of clinical care, whether we like it or not.

This year (2015) was a dynamic and busy one for the field of next - gen sequencing.

Next - gen sequencing technologies have enabled rapid identification of many genes contributing human disease.

The application of next - gen sequencing to RNA libraries (RNA - Seq), chromatin immunoprecipitates (CHiP - Seq), bisulfite - treated DNA, and regions of open chromatin (DNAse - Seq) makes it possible to interrogate many aspects of the genome in high - throughput fashion.

As 2014 draws to a close, I can't help but speculate about the face of next - gen sequencing, genetics, and genomics in 2015.

Researchers also sequenced the genomes of other Panthera - a white Bengal tiger, an African lion, a white African lion, and a snow leopard - using next - gen sequencing technology, and aligned them using the genome sequences of tiger and domestic cat.

The job will entail working on a team of 20 software engineers on next - gen sequence analysis pipelines, focusing on utilizing the information management capabilities of the analysis system to migrate data appropriately between different tiers of storage and eliminate data duplication.

Not exact matches

The technology, available through Genesis Genetics or Good Start Genetics, involves next - generation, or next - gen, sequencing.

«This is where next - gen [eration sequencing] technology comes to help us, because it's actually good at sequencing small pieces and lots of them,» says Mikheyev.

By analogy, the scientists sought to fix RNA in place in the cell, make a tiny ball with many matching DNA replicas of each RNA, then adapt next - gen DNA sequencing so it worked in fixed cells.

Instead of using double - stranded DNA to make genetic libraries that can be fed into a next - gen sequencer, as was standard practice at the time, Meyer and his team first separated the double helix, then prepared the sequence library using each of the single strands, doubling the amount of fragments the group had to sequence.

This study aims to use ecological genomics and next - gen DNA sequencing tools to provide the baseline knowledge on the bio-geographic distribution of chromerids and apicomplexans on the Great Barrier Reef (GBR), their association with different coral hosts, and their role in coral health and disease.

The closest thing to what I'd imagine the minimum of what next gen should look like has been the Watch Dogs sequence and Star Wars 1313 at E3.

The more I've seen of this game since it was first announced — from the action sequences to the next - gen graphics — the more hyped up I've gotten about it.

It doesn't look particularly next gen on the Xbox One, however, and there's a disappointing amount of loading that takes place, both behind the scenes (lengthy sections involving opening doors) and during action sequences (they'll literally stop while «loading» appears in the corner) throughout.

leads broken down into lists: mail sequences, follow ups, drip campaigns, postcards seq, letter seq. (will be necessary as lead gen grows)