The gene activity profiles also provided several novel insights into the biology of outer radial glia.
Not exact matches
To understand why only some motor neurons are vulnerable to ALS, the researchers used DNA microarray
profiling to compare the
activity of tens of thousands of
genes in neurons that resist ALS (oculomotor neurons / eye movement and Onuf's nuclei / continence) with neurons affected by ALS (lumbar 5 spinal neurons / leg movement).
Rao's team used various approaches, including assays of telomerase
activity, measurement of cell growth, and
gene expression
profiling of TSY - 1 treated cells, to determine how it acts.
We took a second muscle biopsy to see what happened to their individual
gene expression
profile, which is a genetic portrait of
gene activity.
Researchers have shown they can distinguish between viral and bacterial infections in children with fever by
profiling the
activity of
genes in a blood sample.
Using an array of techniques, including RNA sequencing and targeted
gene expression
profiling, the researchers searched for links between
gene activity and protein production in these tumors and the clinical outcomes of patients.
Gaining access to the inner workings of a neuron in the living brain offers a wealth of useful information: its patterns of electrical
activity, its shape, even a
profile of which
genes are turned on at a given moment.
Furthermore, the
gene -
activity profiles of the first - generation iPS cells were similar, but not identical, to those of ES cells — and chemical marks called methyl groups on the DNA did not exactly reflect those on ES cells either.
Based on the
gene expression
profile, we demonstrated the up - regulation of hormone sensitive lipase and enhancement of the lipolytic
activity by the treatment of adipocytes with C3G or Cy.