Sentences with phrase «gene affect symptom»

Not exact matches

The study, which is published in the journal Molecular Psychiatry, describes a possible mechanism for how the gene variant produces clinical symptoms by affecting levels of specific proteins in the brain.

Affected individuals do not have a disease: they only carry 1 copy of a hemoglobin gene variant, and unlike individuals with 2 copies of the variant, they do not experience symptoms.

«In this study we weren't looking at how repressing the gene activity affected the symptoms of the disease and this is obviously a critical question as well.

To find out whether how these changes affected people with the Huntington's gene before clinical symptoms begin, Julie Stout of Monash University in Melbourne, Australia, and colleagues selected 119 people who had the gene but no symptoms.

This means affected individuals receive a flawed gene from each parent in order to have symptoms.

NMD also ensures that many mutations in our genes do not cause any disease symptoms — as long as the second copy of the gene affected is still intact and thus a correct version of the body plan is available.

Over the following years, he and his colleagues cloned the HD gene, located its stretch of repeated DNA, showed that the size of that stretch is correlated with age of disease onset and age of death, described how it causes disease, and identified genetic factors that affect how quickly symptoms develop.

The researchers said their finding could lead to new treatments that might help ease symptoms of menopause, but more research is needed to understand how other rare gene variants could affect hot flashes.

However, the gene is transmitted through a female carrier who is often free of symptoms, or mildly affected with a limb weakness.