Sentences with phrase «gene annotation for»

This additional sequencing information, the researchers observed, greatly improved gene annotation for that species of gorilla.

Not exact matches

We tested the top ten percent of the genes expressed in each stage of lactation for significant enrichment of functional annotations.

The paper demonstrates how BinoX can be used to find many biologically meaningful pathway annotations for gene sets from cancer and other diseases, which are not found by other methods.

He and his colleagues, at Johns Hopkins University in Baltimore, have gone back to the lab to look for genes that annotation missed.

Other labs will pitch in for the final assembly and annotation of the genome, as well as analyzing the functions of the new genes discovered.

In a study published online in Genome Research, researchers devised a strategy for genome - wide annotation of primary miRNA transcripts, providing extensive new annotations in human and mouse, and shedding light on mechanisms of regulation of microRNA gene expression.

For each region comparison the percentage of genes found in gap annotation hotspots was reported.

In addition, we have generated a high - quality RNA - Seq gene annotation pipeline that is now routinely used in Ensembl annotation and is proving particularly useful for species with very little protein or cDNA evidence.

The accuracy of the poreFUME pipeline is > 97 % sufficient for the reliable annotation of antibiotic resistance genes.

BioGPS interfaces with the CouchDB instance via the REST - based web services for gene annotation queries and retrieval.

Through systematic annotation of the resulting movies, we developed a phenotypic profiling system, which shows high correlation with cellular processes and biochemical pathways, thus enabling us to predict new functions for previously uncharacterized genes.

Whereas 12 of 16 annotations were confirmed by RT - PCR in human tissues, for only seven genes mouse orthologs could be identified and found to be expressed.

Tet2 is a type of cellular enzyme known as an epigenetic regulator — responsible for making specific chemical annotations to regions of DNA that alter the activity of many different genes.

Careful manual annotation of the human reference sequence provides a solid basis for the identification of disease - associated genes.

RNA - seq reads were aligned to the human genome (hg19 / GRCh37) using TopHat41 (v1.4) and Gencode annotation v1926 was used for gene quantification.

Click «Expression Details» to view all expression annotations and details for this locus, including a visualization of genes that share a similar expression pattern.

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., «cell shape»), a qualifier (e.g., «abnormal»), a mutant type (e.g., null), strain background, and a reference.

This application uses calculated break points to determine fusion genes based on the latest annotation for genomic sequence information, and where relevant the structural variation (SV) events are annotated with predicted RNA and protein sequences.

In light of this, homology - based methods of functional gene annotation will be suitable for only a subset of the genome.

«Register, set up some views, and you'll be finding all sorts of useful annotations for your genes or regions of interest.»

Click «Phenotype Details» to view all phenotype annotations and evidence for this locus as well as phenotypes it shares with other genes.

VAAST (the Variant Annotation, Analysis & Search Tool) is a probabilistic search tool for identifying damaged genes and their disease - causing variants in personal genome sequences.

The study demonstrated the advantages of having an integrated approach to gene prediction and developed a computational framework for combining multiple genome annotations.

«Researchers at the Novartis Institute for Functional Genomics have launched Biology Gene Portal Services, or BioGPS, a gene portal designed to display gene - centric annotation that can be customized for individual users...&raGene Portal Services, or BioGPS, a gene portal designed to display gene - centric annotation that can be customized for individual users...&ragene portal designed to display gene - centric annotation that can be customized for individual users...&ragene - centric annotation that can be customized for individual users...»

By sequencing RNA from infected and uninfected control samples and identifying genes that are differentially regulated by infection status, it is possible for the first time to identify all genes regulated by a specific immune challenge independent of homology - based annotations.

We find evidence of expression for all VR, and almost all OR genes that are annotated as functional in the reference genome, and use the data to generate over 1100 new, multi-exonic, significantly extended receptor gene annotations.

A Uniform System for the Annotation of Human microRNA Genes and the Evolution of the Human microRNAome.

The statistical analysis of gene - families, resistance genes and mobile elements was performed by ShotgunFunctionalizeR 1.03 using custom - made annotations and the Poisson model for direct comparisons [24].

We integrate functional genomic datasets with up - to - date gene and genome annotations, Gene Ontology and pathway annotations, gene orthologs, gene interactions, and a comprehensive set of miRNA - target predictions for human, mouse, zebrafish, and nematgene and genome annotations, Gene Ontology and pathway annotations, gene orthologs, gene interactions, and a comprehensive set of miRNA - target predictions for human, mouse, zebrafish, and nematGene Ontology and pathway annotations, gene orthologs, gene interactions, and a comprehensive set of miRNA - target predictions for human, mouse, zebrafish, and nematgene orthologs, gene interactions, and a comprehensive set of miRNA - target predictions for human, mouse, zebrafish, and nematgene interactions, and a comprehensive set of miRNA - target predictions for human, mouse, zebrafish, and nematode.

Here, we discuss and illustrate the strengths and weaknesses of approaches for the annotation and classification of important elements of protein - coding genes, other genomic elements such as pseudogenes and the non-coding genome, comparative - genomic approaches for inferring gene function, and new technologies for aiding genome annotation, as a practical guide for clinicians when considering pathogenic sequence variation.

Specifically, we have generated clusters of transcripts that behave the same way under the entire spectrum of the sixty - seven experimental conditions; we have assembled genes in groups according to their time of expression during successive days of ES cell differentiation; we have included expression profiles of specific gene classes such as transcription regulatory factors and Expressed Sequence Tags; transcripts have been arranged in «Expression Waves» and juxtaposed to genes with opposite or complementary expression patterns; we have designed search engines to display the expression profile of any transcript during ES cell differentiation; gene expression data have been organized in animated graphs of KEGG signaling and metabolic pathways; and finally, we have incorporated advanced functional annotations for individual genes or gene clusters of interest and links to microarray and genomic resources.

The functional annotations of all the clusters with ≥ 10 transcripts, which were obtained using the on GO classification categories of the g: Profiler tool for all the genes in each cluster, are shown in Table 2 (for downregulated genes during ES cell differentiation) and Table 3 (for upregulated genes).

Group of Designs for Ballet and Various Stage Productions, 1940s - 50s, including two mixed - media examples with annotations, attributed to Miles White, one designed for the dancer Gene Carrons; six More...