Sentences with phrase «gene annotations from»

Not exact matches

The RNA - guided endonuclease Cas9 is a versatile genome - editing tool with a broad range of applications from therapeutics to functional annotation of genes.

The paper demonstrates how BinoX can be used to find many biologically meaningful pathway annotations for gene sets from cancer and other diseases, which are not found by other methods.

In addition, the significant number (> 1000) novel models that came from RNA - Seq that were absent from the zebrafish cDNAs suggests that the deep sequencing offered by RNA - Seq can be used to expand the gene annotation of even well - studied model organisms.

Phenotype data from 449 mutant alleles were acquired, representing 320 unique genes, of which half had no previous functional annotation and data from over 27,000 mice were captured, finding that 83 % of the mutant lines are phenodeviant, with 65 % demonstrating pleiotropy.

Functional annotations from Ensembl BioMart, TAIR10, Phytozome, and MaizeGDB were based on homologs determined through Ensembl Compara gene trees (gramene.org).

Up - to - date gene annotation data were retrieved regularly from common data sources (predominantly NCBI and Ensembl), and then stored in a CouchDB instance and indexed via Lucene.

We considered genes with at least 5 reads mapping in exons and from all biotypes in the annotation.

Draft genome annotation was transferred from P. vivax P01 using RATT21 (version 1), and supplemented with the output of the Augustus22 gene finder, trained on P. vivax P01 as described in23.

While further study will be necessary to better understand the biological role these immune - inducible genes play, it is clear from this study that a transcriptional approach reveals a depth and complexity to the immune response in Nasonia that is not apparent from only comparative and computational annotations.

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence cgene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence cGene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

By sequencing RNA from infected and uninfected control samples and identifying genes that are differentially regulated by infection status, it is possible for the first time to identify all genes regulated by a specific immune challenge independent of homology - based annotations.

This makes them ideal to predict gene function, by transferring known functional annotations from orthologs in model organisms.

This annotation was used to query 107 whole genome sequences from 19 breeds and identified over 5500 alleles across the 550 genes of the seven AR loci: the IG heavy, kappa, and lambda loci; and the TR alpha, beta, gamma, and delta loci.