Sentences with phrase «gene changes activation»

At the core of this cell behavior is how the loss of that single gene changes activation levels of dozens of other genes, suppressing genes associated with metastatic disease and increasing activity of genes linked to normal tissue.

Not exact matches

They found that gene expression is different at 209 sites in chronically lonely people and that many of those changes fit a pattern of elevated immune activation, inflammation, and depressed response to infection.

Activation of the genes enlarged the artery to restore blood flow and mitigated the blood vessel injury that follows blood flow pattern changes.

The research suggests that reducing production of the protein, called myoferlin, affects cancer cells in two primary ways: by changing the activation of many genes involved in metastasis in favor of normal cell behavior, and by altering mechanical properties of cancer cells — including their shape and ability to invade — so they are more likely to remain nested together rather than breaking away to travel to other tissues.

Rutgers University scientists have discovered the three - dimensional structure of a gene - specific transcription activation complex, providing the first structural and mechanistic description of the process cells use to turn on, or activate, specific genes in response to changes in cell type, developmental state and environment.

Analysis of daily gene activation in a patient with severe Ebola virus disease cared for at the National Institutes of Health (NIH) in 2015 found changes in antiviral and immune response genes that pinpointed key transition points in the response to infection.

«In that way, we followed changes in the pleura throughout disease development, observing stages of chronic inflammation, activation of pro-oncogenic signaling pathways, and eventually inactivation and / or loss of genes that are the gatekeepers of cancer development,» MacFarlane says.

Joâ $ ™ s team has used this model to examine changes in gene activation, microRNAs, DNA methylation, and now, metabolic markers.

Results: Within 4 h, activation of CD4 (+) T cells invokes changes in histone modifications and enhancer RNA transcription that correspond to altered expression of the interacting genes identified by promoter capture Hi - C.

The activation will depend on the type of cell the steroids are bind in and changes in how certain genes (especially genes that dominates during the puberty stage) will behave.

Genetics is the study of changes in an organism caused by the activation or deactivation of genes that are passed down to their offspring (without any changes to the organism's DNA).