Sentences with phrase «gene cluster contains»

The gene cluster contains an inversion, or a strand of DNA flipped end - to - end, making it impossible for recombined DNA segments to line up properly on the chromosomes and resulting in a hopeless genetic tangle.

This pharyngeal gene cluster contains six genes ordered in a common pattern in all deuterostomes and includes the genes for four proteins that are critical transcriptional regulators that control activation of numerous other genes.

Not exact matches

Pcdhαc2 is found in a cluster of genes that contain the blueprints for proteins that protrude from the surface of cells.

The genome of Streptomyces chartreusis contains 128 gene clusters, predicted to be relevant for the synthesis of natural products.

Genome sequencing revealed that the isolated B. pumilus contained three unique gene clusters for the production of antimicrobial peptide compounds known as bacteriocins.

The team discovered, for instance, that F. venenatum does not contain some clusters of genes that produce subsidiary compounds, or secondary metabolites, which are produced by F. graminearum during successful wheat infection.

The human T cell receptor beta (TRB, previously known as TCRB) gene locus on chromosome 7 (7q34) includes 65 Vb (variable) gene segments, followed by two separate clusters of genes each containing a Db (diversity) gene, several Jb (joining) genes, and a Cb (constant) region spread over 685 kilobases.

For instance, Cluster 1 contains genes such as cyclin A2, cyclin B1, cyclin E1, cyclin F, polymerase alpha 2, RNA polymerase II polypeptide H, and RNA polymerase III polypeptide G, whereas Cluster 3 genes include Nanog, Sox2, Pou5f1 (Oct4), Klf2, Zpf42 (Rex1) and Esrrb.

For example, cluster 5 of the concise «Time Series», which consists of transiently induced genes around day 3 of differentiation, similarly to Global Cluster 30, contains the same transcripts, but in addition, it also includes T - brachyury, Axin2, Mesp2, Fgf8, Wnt8a, Sp5, Sp8, Follistatin, Mix1 ancluster 5 of the concise «Time Series», which consists of transiently induced genes around day 3 of differentiation, similarly to Global Cluster 30, contains the same transcripts, but in addition, it also includes T - brachyury, Axin2, Mesp2, Fgf8, Wnt8a, Sp5, Sp8, Follistatin, Mix1 anCluster 30, contains the same transcripts, but in addition, it also includes T - brachyury, Axin2, Mesp2, Fgf8, Wnt8a, Sp5, Sp8, Follistatin, Mix1 and Lim1.

For example, clusters containing genes that are upregulated during the course of ES cell differentiation (Table 3) include in order of time of expression: cluster 30 that represents genes which take part in the formation of the three embryonic germ layers during gastrulation, i.e., Goosecoid, Cerberus like 1 homolog, Wnt3, Mesp1, Mixl1, mEomes and Even - skipped 1; cluster 15 containing molecular regulators of early mesoderm development including Bmp2, Bmp5, Msx1, Msx2, Cripto, Tbx20, Hey2, Smad6, Vegfr2 (Kdr), Foxf1 and Hand1; cluster 20, which comprises regulatory and structural genes linked to hemopoiesis such as Gata1, Nfe2, Klf1, Tie1, hemoglobins (Hba - x, Hbb - b1) and Glycophorin A; cluster 12, which is rich in genes involved in cardiac development, e.g., Mef2c, Myl4, cardiac Troponin T2, Tropomodulin 1, myosin binding protein C, Bves, Angiopoietin 1 and Angiopoietin 2; and, cluster 4, which consists mostly of genes associated with neuronal development and differentiation, for example, Neurog1, Neurog2, Olig2, Nkx6.1, Neurod4, Pou3f2, Pou3f4, Cacna2d3, Cacng4, Kcnq2 and EphA5.

In addition to well - described genes, clusters often contain transcripts the function of which has not yet been associated with a specific biological process thus providing novel unexplored links to known molecular pathways.

5 % of the permuted data sets gave rise to clusters containing no more than two genes at a similarity score > 0.85071 (Supplemental File S6).

Unsupervised hierarchical clustering of the 5,959 genes, using 100 random permutations, gave rise to 115 groups, containing a total number of 2,855 transcripts, with a probability of 95 % or higher that clustering was not random (Supplemental File S2).