Characterization of the hcnABC
gene cluster encoding hydrogen cyanide synthase and anaerobic regulation by ANR in the strictly aerobic biocontrol agent Pseudomonas fluorescens CHA0.
This search identified a previously undiscovered
gene cluster encoding a new botulinum neurotoxin and accessory proteins in the genome of a species of Enterococcus bacteria isolated from cow faeces.
Not exact matches
The
genes that
encode the botulinum toxin protein along with accessory proteins that protect the botulinum toxin and ensure it functions, are organised as a
gene cluster.
The dedicated tailoring enzymes are
encoded by
genes clustered with the assembly line
genes for coordinated regulation.
Brady and coworkers amplify and sequence bacterial DNA from environmental soil samples and then look for
gene clusters that
encode enzyme systems likely to biosynthesize natural products with preselected characteristics.
Upregulated
genes clustered into at least 7 functional groups, including immediate early
genes or transcription factors, cell - cycle related
genes, stress - responsive protein
genes, cell signaling protein
genes, cell adhesion and cell surface protein
genes,
genes involved in translation and protein turnover, and
genes encoding metabolic proteins.
Bacteria use small molecule chemicals to mediate these interactions and the genetic information required for their production is typically
encoded in one physical location of the bacterial chromosome, in biosynthetic
gene clusters (BGCs).