Gene clusters refer to groups of genes that are located close to each other on a chromosome. These genes often work together or are involved in similar functions. It's like a team of genes that are grouped together to carry out specific jobs in our cells.
Full definition
Because most of these substances can be traced back to a
single gene cluster, the scientists also studied the molecular reasons for the diversity of products.
Genome sequencing revealed that the isolated B. pumilus contained three unique
gene clusters for the production of antimicrobial peptide compounds known as bacteriocins.
This pharyngeal
gene cluster contains six genes ordered in a common pattern in all deuterostomes and includes the genes for four proteins that are critical transcriptional regulators that control activation of numerous other genes.
The so - called SERPINB
gene cluster on chromosome 18 was identified as a specific genetic risk locus for food allergies.
This search identified a previously undiscovered
gene cluster encoding a new botulinum neurotoxin and accessory proteins in the genome of a species of Enterococcus bacteria isolated from cow faeces.
The invasion of epithelial cells and immune cells are controlled by two separate
gene clusters called Salmonella Pathogenicity Islands 1 and 2 (SPI1, SPI2) respectively.
The dedicated tailoring enzymes are encoded by
genes clustered with the assembly line genes for coordinated regulation.
«Using improved computer software, we have enhanced gene predictions and secondary
metabolite gene cluster predictions in both species to a level not found in most other filamentous fungal species,» says Robert King, the team's lead bioinformatician at Rothamsted.
Upregulated
genes clustered into at least 7 functional groups, including immediate early genes or transcription factors, cell - cycle related genes, stress - responsive protein genes, cell signaling protein genes, cell adhesion and cell surface protein genes, genes involved in translation and protein turnover, and genes encoding metabolic proteins.
This research shows that the
pharyngeal gene cluster is unique to the deuterostomes and it could be linked to the development of the pharynx, the region that links the mouth and nose to the esophagus in humans.
«In this new study we found strong evidence that variation in the
glycophorin gene cluster influences malaria susceptibility.
Two
new gene clusters involved in the degradation of plant cell wall from the fecal microbiota of Tunisian dromedary
Two new
gene clusters involved in the degradation of plant cell wall from the fecal microbiota of Tunisian dromedary — Rihab Ameri — PLoS One
Four of these six regions are located in
known gene clusters: the protocadherin alpha cluster, two olfactory receptor clusters and a recently identified human microRNA cluster (Figure 2).
Genetic Variants of the FADS1
FADS2 Gene Cluster Are Associated with Altered (n - 6) and (n - 3) Essential Fatty Acids in Plasma and Erythrocyte Phospholipids in Women during Pregnancy and in Breast Milk during Lactation
As well as understanding the implications of finding this new variant of the
botulism gene cluster in a non-clostridial species of gut bacterium, the team are interested in exploring how it might help in developing new treatments for diseases.
«It is an intriguing question as to how this Enterococcus strain acquired a botulinum
neurotoxin gene cluster, what benefit it brings to this bacterium, and further work is required to explore the implications of our important finding with regard to the possibility of its transfer between bacteria.
But for mice in which the
whole gene cluster was deleted, serotonin axons don't keep their distance from each other.
One
gene cluster connected with the development of the pharynx in vertebrates and acorn worms is particularly interesting.
But the
Hox gene clusters may contain a far deeper message about the DNA double helix.
[Nicholas I. Mundy et al., Red Carotenoid Coloration in the Zebra Finch Is Controlled by a Cytochrome
P450 Gene Cluster]
Junji Hirota at Tokyo Tech and team focused on discovering a long - range enhancer for a
large gene cluster, finding an evolutionary conserved sequence motif in mammalian evolution, and elucidating enhancer - dependent allelic preference or exclusion mechanism for odor - detecting receptor genes.
The research team had previously identified a section of DNA adjacent to the
HoxD gene cluster, which formed a particular 3D structure in order to interact with and activate certain Hox genes.
A different research group recently found that the
Osiris gene cluster is under strong selection in an isolated population of the fly D. yakuba that has just begun adapting to a diet of poison - laden noni, another clue that learning more about these genes may be crucial for understanding OA resistance and this compelling model of ecological adaptation.
His research career has been principally concerned with understanding the mechanisms by which tissue and developmental stage specific gene expression is achieved and regulated with early work focusing on the regulation of the b -
globin gene clusters.
It should be noted, however, that the typing method used here is based on the analysis of a noncoding spacer region within the
rRNA gene cluster of B. burgdorferi [16, 19, 28, 35].
Characterization of the
hcnABC gene cluster encoding hydrogen cyanide synthase and anaerobic regulation by ANR in the strictly aerobic biocontrol agent Pseudomonas fluorescens CHA0.
Single nucleotide polymorphisms in the
FADS gene cluster are associated with delta - 5 and delta - 6 desaturase activities estimated by serum fatty acid ratios.
Some people believe a whole genome was duplicated and others believe
smaller gene clusters were duplicated.
Although M. frappieri JAM7 does not grow under anoxic conditions with NO 3 −, which concurs with the
absence gene cluster encoding a dissimilatory NO 3 − reductase, the occurrence of nirK may be associated with the detoxification mechanism.
Rapid transcriptional plasticity of
duplicated gene clusters enables a clonally reproducing aphid to colonise diverse plant species
Phrases with «gene clusters»