Sentences with phrase «gene content of»

We are also analyzing the gene content of hundreds of microbiome species from humans all over the world to test if the hypotheses we formed from the Khoisan study hold up.
The gene content of these regions, which in several cases reached gene - level resolution, suggests an important role for epigenetic and transcription regulation in the maintenance of reproductive barriers.
It finally reveals the gene content of the two different Y chromosome systems that evolved in mammals,» says Dr Grützner, who has led research into monotreme sex chromosomes for more than 10 years.
Dr Luis Pedro Coelho, corresponding author of the study, commented: «We found many similarities between the gene content of the human and dog gut microbiomes.

Not exact matches

But the vitamin A content was still low, so they turned to a gene found in corn, which increased the amount of vitamin A 23 times.
According to the The Telegraph, among other news outlets, scientists in China have introduced human genes into a herd of cows whose milk contains some of the same properties as breast milk: higher fat content and two human proteins, lysozyme and lactoferrin, which help babies» immune systems.
«Antibiotics use affects the abundance of resistant bacteria in soil: The use of animal manure increases the soil content of antibiotic - resistant genes
Using metabolic function analyses of identified genes, we compared our human genome with the average content of previously sequenced microbial genomes.
The degree of fat content in the liver correlated with the degree of DPP4 gene methylation and the amount of enzymes produced by the liver.
We report a 10.1 - gigabase assembly of the 14 chromosomes of wild tetraploid wheat, as well as analyses of gene content, genome architecture, and genetic diversity.
Compared with controls, fish with only one copy of each gene exhibit hyperactivity, increased propensity for seizures, increased body and head size, and fat content.
Wheat breeder Jorge Dubcovsky of the University of California, Davis, led an international team that discovered the gene — dubbed gpc - B1 for its effect on grain protein content — in a wild emmer wheat that has grown naturally in the Middle East for millennia.
After six to eight weeks, the microbial content of the mice's feces were analyzed by 16S ribosomal RNA gene sequencing, which showed that approximately 20 kinds of oral bacteria were present in these mice.
A new study reveals that decades of breeding the fruits for uniform color have robbed them of a gene that boosts their sugar content.
Although the available introns of these genes had significant correlations among GC content and body mass and among GC content and chromosome position, they exhibited less heterogeneity overall (fig.
«The mitogenome of V. scurruloideum has proven an unexpected goldmine of surprises, setting new benchmarks for the extremes of genome size, gene content, protein divergence and other biological mechanisms,» he said.
Because photosynthesis helps activate the genes needed to develop color and flavor compounds in the fruit, a shutdown will wash out the grapes» color and alter the acid and sugar content, resulting in the loss of some flavor and aroma.
The coherence of the NRY's gene content contrasts with the apparently haphazard content of most eukaryotic chromosomes.
Gene content and order are highly conserved between Mmu 16 and the syntenic blocks of the human genome.
Currently, the gene content and transcription pattern of the bovine Y chromosome is the only non-primate Y chromosome that researchers have studied in depth, according to Liu.
However, genetic isolation and lineage - specific evolution resulted in the unique structure of the bovine Y chromosome, which determines the gene content and transcriptional activity of the Y chromosome among cattle, according to Liu.
Other characteristic patterns of variants included genes involved in immune system activity and the fat content of breast milk.
Scientists have tripled the iron content of rice by inserting a soybean gene into the plant's DNA.
Song explained the structural knowledge of DNMT3A will allow scientists to control DNA methylation content, gene expression, and cell differentiation — all of which are linked to diseases and finding cures for them.
In vertebrates, gene content has remained relatively constant, while the fraction of non-coding DNA varies drastically [1 — 3].
The consequences of gene extinction on DM1 phenotype is then monitored at the molecular level by quantitative PCR or at the cellular level by high content screening in 96 or 384 - well plate format.
Not content to provide just the missing evidence for a 60 - year - old puzzle, Wilhelm and his colleagues went on to describe what a subset of these genes do in C. elegans and how they might be driving the ageing process.
In a first for machine - learning algorithms, a new piece of software developed at Caltech can predict behavior of bacteria by reading the content of a gene.
The complete genome sequence was determined and shows a high level of conservation in both sequence and overall gene content in comparison to other Chlamydiaceae.
This revealed, despite the high overall genomic conservation of the region, remarkable differences of the gene content between human and mouse.
Stem cell researchers from UCLA used a high resolution technique to examine the genome, or total DNA content, of a pair of human embryonic stem cell lines and found that while both lines could form neurons, the lines had differences in the numbers of certain genes that could control such things as individual traits and disease susceptibility.
Second, are you tired of visiting a dozen different gene portals, each of which have 80 % of the same data, for the 20 % unique content?
Since the expression of genes representing oxidative phosphorylation is decreased in adipose tissue of T2D twins (Table 2 and Fig. 1A), we quantified mtDNA content to follow up these results.
Lower sequence coverage (survey sequencing) of related species can yield a wealth of information about gene content and putative regulatory elements.
Array CGH provided a much better look at the gene content on the chromosomes of human embryonic stem cells, with a resolution about 100 times better than standard clinical methods.
Here, we report a deeper analysis of its gene content and compare it to other P. fluorescens strains to unveil the genetic elements that might explain UM270's great colonizing and plant growth - promoting capabilities.
«For any characteristic of the tomato, whether it's taste, natural pest resistance or nutritional content, we've captured virtually all those genes,» says Giovannoni.
We hope our content will be of particular interest to industrial or academic scientists active in R&D in molecular biotechnology, gene transfer and expression, applied microbiology, environmental biotechnology, biofuels and bioenergy, nanotechnology, bioprocessing, chemical biotechnology, tissue engineering and regenerative medicine, nucleic acid therapeutics and vaccines, plant biotechnology, and patenting and regulatory issues.
Finally, we show that a high proportion of these novel induced genes are taxonomically restricted, highlighting the rapid evolution of immune gene content.
Biased gene conversion and GC - content evolution in the coding sequences of reptiles and vertebrates.
For custom gene expression projects the Genomics Core has a platform that uses sets of human and mouse custom arrays whose probe content is aimed at gene expression studies in the areas of cancer, immunology and other complex diseases.
Cenix BioScience is a contract research organization focused on the discovery and pre-clinical development of novel therapeutics, specializing in advanced applications of RNA interference (RNAi) gene silencing combined with high content phenotyping in cultured cells in vitro and in animals in vivo.
We used ∼ 9-fold whole - genome Sanger shotgun coverage to produce a ∼ 167 - megabase - pair assembly that typically represents each locus once rather than splitting alleles (Supplementary Notes 2 and 3) and captures ∼ 97 % of the protein - coding gene content (Supplementary Note 2.5).
Metazoans can now be defined by a long list of genomic synapomorphies — gene content, intron — exon structure and syntenies — as well as characteristics common to all animal life such as sex, development, controlled cellular proliferation, differentiation and growth, and immunity.
Dmitry: as the paper itself notes, the most likely mechanism for the ability of hydroxypropyl - β - cyclodextrin to lower Aβ burden in the mouse model is AD finding is by normalizing membrane cholesterol content and reducing the appearance of abnormal cathepsin D - positive lysosomes, leading to reduced beta - secretase cleavage of APP and an upregulation of genes involved in cholesterol trafficking and Aβ clearance.
The genome comprises 4,411,529 base pairs, contains around 4,000 genes, and has a very high guanine + cytosine content that is reflected in the biased amino - acid content of the proteins.
Many bacterial species are composed of multiple lineages distinguished by extensive variation in gene content.
Researchers expect they will find genes they can tweak to increase the nutritional content and yields of food crops.
In addition, the remarkably high (~ 80 %) A + T content of parasite genes can result in long stretches of repetitive amino acids [13], and codons that are not frequently used by organisms popular for heterologous protein expression.
To confirm the accuracy, fidelity, and sensitivity of the method, we carried out several tests including the dilution of a pool of cDNA to levels equivalent to single cell content prior to measurement of gene expression in ten replicates.
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