Sentences with phrase «gene controls whether»

The Newcastle University study suggests that an as - yet undiscovered gene controls whether a man's sperm contains more X or more Y chromosomes, which affects the sex of his children.

Not exact matches

Before this can happen though, Teixeira said that his team will first have to determine whether the Stk11 gene or the other genes and proteins it controls are similarly affected in the human form of BPH.
After isolating per, we began to question whether the gene acted alone in controlling the day - night cycle.
The findings by a team of Massachusetts General Hospital (MGH) investigators, which will be published in the April 24 issue of Cell and are receiving advance online release, support the importance of epigenetics — processes controlling whether or not genes are expressed — in cancer pathology and identify molecular circuits that may be targeted by new therapeutic approaches.
The pilot project tested a dozen or so of the most commonly used gene promoters (regions of DNA that facilitate gene transcription) and segments of DNA that encode ribosome - binding sites (sequences of messenger RNA that control protein translation) to determine whether they behave consistently in different cellular contexts.
Purdue University researchers have pinpointed the gene that controls whether soybean seed coats are hard or permeable, a finding that could be used to develop better varieties for southern and tropical regions, enrich the crop's genetic diversity and boost the nutritional value of soybeans.
The proposed strategy reflects a continuing move toward combination therapies, particularly when it comes to epigenetic approaches, which target the mechanisms that control whether genes are switched «on» or «off.»
The researchers previously discovered that a gene called ALX1 controls whether beaks are blunt or pointy (SN: 3/7/15, p. 7).
Such high levels of genetic variation poise mosquito populations to rapidly evolve in response to our efforts to control them whether that be with insecticides or any other control measure, including gene drive.»
Among the approximately 100 imprinted genes discovered so far, about half of them, including Igf2, make proteins in the brain, raising the question of whether imprinting errors in genes that control the structure and function of the brain might contribute to mental illness.
For all 20,000 individual genes, they determined whether those genes were heritable — controlled by the DNA «dimmer switch» — or largely affected by environment.
There has been some controversy among neuroscientists over whether gene expression could functionally control plasticity or connectivity between neurons.
One way to control expression, he explains, is through microRNA, small pieces of noncoding genetic material that control whether a gene's protein is generated from the DNA blueprints inside cell nuclei.
BET inhibitors reduce tumour growth by blocking BET proteins, a family of proteins that control whether genes are switched on or off.
In recent decades we have learned that it does much more, from controlling what form a protein will take to influencing whether a particular gene is able to generate a protein.
Methylations are chemical changes that control gene activity, that is, whether they are active or not.
Of these, a high proportion are so - called command - and - control genes that help bacteria decide whether to form colonies or to continue seeking better shelter, possibly making Pseudomonas «smarter» than other bacteria.
Instead, the differences appear to be in the promoter regions for these genes, an area of DNA close to the gene that helps control whether it ultimately used to make protein.
Tapio, meanwhile, has adapted standard proteomics techniques so that they can be applied to some of the old tissues, and several groups are studying whether micro-RNAs — which help to control gene expression and are relatively stable — are present in the samples.
It's hard to say what is selecting for these traits, and to discern whether they are being passed down through the women's genes, but because Stearns controlled for many social and cultural factors, it is likely that his results document genetic, rather than cultural evolution at work.
Interestingly, the results of our promoter analysis for all these genes revealed that 9 of 17 genes (COL13A1, CSF3, FSCN1, HG18, LTBP1, PELI1, PLOD2, SCNN1A, and TNFSF10) have perfectly matched consensus sequences of KLF4 binding site on the promoter regions, suggesting a potential possibility of controlling these genes by KLF4 although it is not clear whether these genes are cause or consequence of brain metastasis at this point.
Using data from blood and brain tissue, a team led by researchers at Johns Hopkins Bloomberg School of Public Health found that they could gain insights into mechanisms that might help explain autism by analyzing the interplay between genes and chemical tags that control whether genes are used to make a protein, called epigenetic marks.
The identification of a gene that controls whether petunia flowers attract pollination by hawkmoths at night or by hummingbirds during the day is reported in a paper published online this week in Nature Genetics.
The current work shows that changes in the genetic code of a particular gene can control epigenetic marks at different genes, implying that a gene's genetic code can affect whether other genes are turned on and off, which makes it important to understand the function of all genes involved, not just the one with the so - called misspelling.
The researchers identified 24 potential reprogramming factors — proteins that control whether other genes in the cell are turned on or off.
Gene Set Enrichment Analysis (GSEA) is a microarray data - mining technique used to determine whether there is coordinated differential expression or «enrichment» in a set of functionally related genes when comparing control and experimental samples [35].
Rather, how genes are controlled may help determine whether we have hair or fur or other distinct characteristics.
To examine whether CCHa2 acts together with CCHa2 - R in the control of Dilps in vivo, we generated animals carrying a defective CCHa2 gene using the CRISPR / Cas system [29].
To explore whether salt affects the circadian rhythm of Daphnia, researchers first established that the plankton is governed by a core set of clock - control genes that anticipates the day / night cycle.
Although still not entirely understood, it is widely accepted that DNA methylation plays a role in controlling whether or not a gene is turned on.
In a developing embryo, for example, a researcher could determine whether or not newly synthesized or long - lived transcription factors control gross changes in gene expression as new body sections are formed.
In this study, we examined whether the potential to utilise global regulatory mechanisms to control gene expression through chromatin organisation varies between housekeeping and tissue specific genes (Hkg and Tsg respectively) by virtue of their organisation.
Some things that affect whether your metabolism is speedy or sluggish include things you don't control, like your age, sex, and genes.
Education Next's Mike Petrilli talks with Gene about his experience as a school board member — and now, school board president — and whether he sees a future for this last bastion of local control.
A second gene known as Edn3 was identified as controlling whether the animal grows dark fur or light at the site of its blotches and stripes.
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