The Newcastle University study suggests that an as - yet undiscovered
gene controls whether a man's sperm contains more X or more Y chromosomes, which affects the sex of his children.
Not exact matches
Before this can happen though, Teixeira said that his team will first have to determine
whether the Stk11
gene or the other
genes and proteins it
controls are similarly affected in the human form of BPH.
After isolating per, we began to question
whether the
gene acted alone in
controlling the day - night cycle.
The findings by a team of Massachusetts General Hospital (MGH) investigators, which will be published in the April 24 issue of Cell and are receiving advance online release, support the importance of epigenetics — processes
controlling whether or not
genes are expressed — in cancer pathology and identify molecular circuits that may be targeted by new therapeutic approaches.
The pilot project tested a dozen or so of the most commonly used
gene promoters (regions of DNA that facilitate
gene transcription) and segments of DNA that encode ribosome - binding sites (sequences of messenger RNA that
control protein translation) to determine
whether they behave consistently in different cellular contexts.
Purdue University researchers have pinpointed the
gene that
controls whether soybean seed coats are hard or permeable, a finding that could be used to develop better varieties for southern and tropical regions, enrich the crop's genetic diversity and boost the nutritional value of soybeans.
The proposed strategy reflects a continuing move toward combination therapies, particularly when it comes to epigenetic approaches, which target the mechanisms that
control whether genes are switched «on» or «off.»
The researchers previously discovered that a
gene called ALX1
controls whether beaks are blunt or pointy (SN: 3/7/15, p. 7).
Such high levels of genetic variation poise mosquito populations to rapidly evolve in response to our efforts to
control them
whether that be with insecticides or any other
control measure, including
gene drive.»
Among the approximately 100 imprinted
genes discovered so far, about half of them, including Igf2, make proteins in the brain, raising the question of
whether imprinting errors in
genes that
control the structure and function of the brain might contribute to mental illness.
For all 20,000 individual
genes, they determined
whether those
genes were heritable —
controlled by the DNA «dimmer switch» — or largely affected by environment.
There has been some controversy among neuroscientists over
whether gene expression could functionally
control plasticity or connectivity between neurons.
One way to
control expression, he explains, is through microRNA, small pieces of noncoding genetic material that
control whether a
gene's protein is generated from the DNA blueprints inside cell nuclei.
BET inhibitors reduce tumour growth by blocking BET proteins, a family of proteins that
control whether genes are switched on or off.
In recent decades we have learned that it does much more, from
controlling what form a protein will take to influencing
whether a particular
gene is able to generate a protein.
Methylations are chemical changes that
control gene activity, that is,
whether they are active or not.
Of these, a high proportion are so - called command - and -
control genes that help bacteria decide
whether to form colonies or to continue seeking better shelter, possibly making Pseudomonas «smarter» than other bacteria.
Instead, the differences appear to be in the promoter regions for these
genes, an area of DNA close to the
gene that helps
control whether it ultimately used to make protein.
Tapio, meanwhile, has adapted standard proteomics techniques so that they can be applied to some of the old tissues, and several groups are studying
whether micro-RNAs — which help to
control gene expression and are relatively stable — are present in the samples.
It's hard to say what is selecting for these traits, and to discern
whether they are being passed down through the women's
genes, but because Stearns
controlled for many social and cultural factors, it is likely that his results document genetic, rather than cultural evolution at work.
Interestingly, the results of our promoter analysis for all these
genes revealed that 9 of 17
genes (COL13A1, CSF3, FSCN1, HG18, LTBP1, PELI1, PLOD2, SCNN1A, and TNFSF10) have perfectly matched consensus sequences of KLF4 binding site on the promoter regions, suggesting a potential possibility of
controlling these
genes by KLF4 although it is not clear
whether these
genes are cause or consequence of brain metastasis at this point.
Using data from blood and brain tissue, a team led by researchers at Johns Hopkins Bloomberg School of Public Health found that they could gain insights into mechanisms that might help explain autism by analyzing the interplay between
genes and chemical tags that
control whether genes are used to make a protein, called epigenetic marks.
The identification of a
gene that
controls whether petunia flowers attract pollination by hawkmoths at night or by hummingbirds during the day is reported in a paper published online this week in Nature Genetics.
The current work shows that changes in the genetic code of a particular
gene can
control epigenetic marks at different
genes, implying that a
gene's genetic code can affect
whether other
genes are turned on and off, which makes it important to understand the function of all
genes involved, not just the one with the so - called misspelling.
The researchers identified 24 potential reprogramming factors — proteins that
control whether other
genes in the cell are turned on or off.
Gene Set Enrichment Analysis (GSEA) is a microarray data - mining technique used to determine
whether there is coordinated differential expression or «enrichment» in a set of functionally related
genes when comparing
control and experimental samples [35].
Rather, how
genes are
controlled may help determine
whether we have hair or fur or other distinct characteristics.
To examine
whether CCHa2 acts together with CCHa2 - R in the
control of Dilps in vivo, we generated animals carrying a defective CCHa2
gene using the CRISPR / Cas system [29].
To explore
whether salt affects the circadian rhythm of Daphnia, researchers first established that the plankton is governed by a core set of clock -
control genes that anticipates the day / night cycle.
Although still not entirely understood, it is widely accepted that DNA methylation plays a role in
controlling whether or not a
gene is turned on.
In a developing embryo, for example, a researcher could determine
whether or not newly synthesized or long - lived transcription factors
control gross changes in
gene expression as new body sections are formed.
In this study, we examined
whether the potential to utilise global regulatory mechanisms to
control gene expression through chromatin organisation varies between housekeeping and tissue specific
genes (Hkg and Tsg respectively) by virtue of their organisation.
Some things that affect
whether your metabolism is speedy or sluggish include things you don't
control, like your age, sex, and
genes.
Education Next's Mike Petrilli talks with
Gene about his experience as a school board member — and now, school board president — and
whether he sees a future for this last bastion of local
control.
A second
gene known as Edn3 was identified as
controlling whether the animal grows dark fur or light at the site of its blotches and stripes.