Sentences with phrase «gene duplications during»

This is a unique scientific paradigm: the first publication determining the role of human - specific gene duplications during brain development came out of our laboratory recently (Charrier et al., 2012) and represents a milestone in our understanding of the genetic and neurobiological mechanisms underlying the emergence of human - specific traits of brain development, for example neoteny during synaptic maturation (Benavides - Piccione et al., 2002; Petanjek et al., 2011).

We are currently using this new paradigm to define the expression and function of other hominoid - and human - specific gene duplications during brain development and evolution.

Not exact matches

I was fascinated to read how the double duplication of the SRGAP2 gene, which helps drive development of the brain's neocortex, appears to have propelled our ancestors» development at two distinct times during the past few million years (12 May, p 10).

Recent breakthroughs in evolutionary genomics show that a burst of gene duplications occurred in the human lineage during its separation from non-human primates approximately 6 million years ago (Bailey et al., 2002; Fortna et al., 2004; Marques - Bonet et al., 2009).

During her graduate studies she investigated the contribution of gene duplication to the origin and evolution of human phenotypes.