Not exact matches
Shares of pioneering CRISPR
gene -
editing firm Editas fell 7 % in early Tuesday trading after the
company announced that it would delay an initial FDA filing for clinical trials of one of its lead drugs, LCA10, to the middle of next year (Editas had originally planned to file by the end of 2017).
• Calyxt, the New Brighton, Minn. - based
company based on
gene -
editing foods, filed for a $ 50 million IPO Friday.
There are a handful of public
companies in the industry, including
gene editing Intellia Therapeutics, which raised $ 108 million in its 2016 IPO.
Now that the barrier of
editing genes in the hospital setting has been broken, these
companies and more have pipelines of
gene -
editing innovation coming to a hospital near you in the next few years, as clinical trials are approved and new ways to cure formerly incurable diseases go mainstream in our lifetimes.
• Excision BioTherapeutics, a Philadelphia - based life science
company focused on the development and commercialization of advanced
gene editing therapeutics for the treatment of life - threatening disease caused by neurotropic viruses, raised $ 10 million in seed funding.
• Calyxt, the New Brighton, Minn. - based
company based on
gene -
editing foods, said it would offer 7 million shares at $ 8 — at the low end of its range of $ 8 to $ 10.
Without doubting the importance of what they call «the
gene -
editing explosion,» they aren't yet sure of the value of Crispr - Cas9 to their
company.
Ultimately, enhancements of many kinds will «definitely» happen in the future, says Fyodor Urnov of Sangamo BioSciences, a
company that is working in the
gene editing space.
Many groups, including Urnov's
company, are already using
gene -
editing tools to develop therapies that correct genetic defects in people (such as by
editing white blood cells).
The
company aims to use CRISPR
gene -
editing to craft RNA therapeutics that can be delivered into the central nervous system — clearly a daunting task for most drug makers.
The track record of earlier
gene -
editing approaches suggests that the CRISPR
companies pursuing medical therapies have a long road ahead.
The first author is Edward Lanphier, the «president and CEO of Sangamo BioSciences in Richmond, California, a
company that hopes to use
gene -
editing technology to treat patients.»
They hope that such a discussion would help the public understand the difference between genome
editing in a person's somatic cells — cells other than sperm and egg cells — and
editing in cells that could pass the changes on to future generations, says Lanphier, who is president and CEO of Sangamo BioSciences in Richmond, California, a
company that hopes to use
gene -
editing technology to treat patients.
«I am thrilled to join Caribou at such an exciting time for the
Company and the field of CRISPR
gene editing,» said Dr. Kanner.
Several biotechnology
companies are using the
gene editing technique in an effort to develop therapies for treating genetic diseases, including CRISPR Therapeutics, Intellia Therapeutics and Editas Medicine.
«With extensive experience at both large and small agriculture and industrial biotech
companies, she is uniquely positioned to help Caribou capitalize on the potential opportunities for CRISPR - Cas
gene editing to develop improved crops and bio-based products.»
CRISPR Therapeutics is pioneering a new class of medicines, to conduct the first
company - sponsored clinical trial of a CRISPR
gene -
edited therapy.
PULLMAN, Wash. — A
gene editing technology developed at Washington State University is being licensed to Genus plc, a global animal genetics
company, to develop cattle that are more resistant to bovine respiratory disease (BRD).