Sentences with phrase «gene editing tools such»

Not exact matches

The aim of current de-extinction efforts is to use gene - editing tools to engineer living species to re-create extinct cousins, such as engineering a woolly mammoth from an elephant.

Recent advances combining the gene - editing tool CRISPR — Cas9 (for, clustered, regularly interspaced, short palindromic repeats with a guiding enzyme called Cas9) are now making it easier for scientists to modify a genome such that nearly all offspring inherit the desired trait.

Although the study looked at CRISPR - Cas9 gene editing, the researchers believe their findings extend to other gene - editing tools such as zinc - finger nucleases (ZFN) and TAL effector nucleases.

Many groups, including Urnov's company, are already using gene - editing tools to develop therapies that correct genetic defects in people (such as by editing white blood cells).

With gene - editing tools such as CRISPR, scientists can now eliminate immune - provoking sugars from the surface of pig cells, introduce human genes that regulate blood coagulation to prevent dangerous clots, and snip out viral sequences that some fear could infect a human host.

CRISPRs are bacterial immune systems that contain many defense enzymes such as the Cas9 «molecular scissors,» which scientists including Hsu have engineered as a powerful DNA - targeting gene - editing tool.

«For our new systemic viral vectors — AAV PHP.S and AAV PHP.eB — there are many potential uses, from mapping circuits in the periphery and fast screening of gene regulatory elements to genome editing with powerful tools such as CRISPR - Cas9,» says Gradinaru.

Compared with gene editing with tools such as CRISPR / Cas9, constructing a full genome could allow more widespread manipulation, Church explains.

More and more scientists are using the powerful new gene - editing tool known as CRISPR / Cas9, a technology isolated from bacteria, that holds promise for new treatment of such genetic diseases as cystic fibrosis, muscular dystrophy...

«Now that powerful gene - editing tools, such as TALENs, are readily available, the next step is to streamline their implementation into stem cell research,» said Dirk Hockemeyer, PhD, assistant professor of molecular and cellular biology at the University of California, Berkeley, who was not involved in this study.

As liposomes are large structures, their composition can be optimised to deliver larger cargos such as mRNA (to replace or up - regulate gene expression) and the tools needed to trigger gene editing through CRISPR / Cas9.