Sentences with phrase «gene expression»

For instance, protein and DNA modifications involved in gene expression in kidneys must at some point be turned off.

An analysis of gene expression of the known fungal partner in the two species showed no differences.

The same can be said for patterns of gene expression changes in the same brain region for different age frames.

Then, she was more interested in the rapid change in gene expression patterns stimulated by environmental stress, which is anything but subtle.

Both were known to be active in regulating gene expression in the liver, kidney, and intestine.

They then examined genetic variants throughout the human genome for their effects on gene expression in these two representative populations of immune cells.

Controls gene expression by turning on some genes while turning off the expression of other genes.

More recent research on the epigenetic modification of gene expression by early maternal care in animals suggests the possibility of similar processes affecting human development.

This cellular thermometer is sensitive enough to react to changes in body temperature between 36 and 38 ° C with altered gene expression.

A new computational method can improve the accuracy of gene expression analyses, which are increasingly used to diagnose and monitor cancers and are a major tool for basic biological research.

The environmental factors also affected gene expression in the brain.

This can then be used to create computational estimates of gene expression levels from any whole genome sequence or chip dataset.

We have developed a novel «integrated» approach for gene expression profiling analysis that combines both «unbiased» and «biased» profiling (22)[Fig. 5].

Monitoring these expression ratios in live cells would provide prospective gene expression data as opposed to traditional retrospective characterization.

The study suggests that methods based on variance may help get the most from existing and future global gene expression studies.

The new research focused on just nine genes, those most strongly associated with autism in recent sequencing studies, and investigated their effects using precise maps of gene expression during human brain development.

Then — noting the side of the colon that the tumor originated from — the researchers look at gene expression.

It's not clear, for example, if the process of analyzing gene expression from a tumor biopsy to decide on a course of treatment can be protected by a patent.

In addition, he has also discovered another protein that can be affected by drugs and directly influences gene expression in both cancer and heart failure.

The transmission of different states of gene expression through multiple cell divisions and across generations has been termed «epigenetic,» since the underlying DNA sequence is identical in both states.

The researchers used the worm's genomic information to study how gene expression changed during regeneration.

Although much similarity exists, mouse and human gene expression differs significantly in specific biological pathways.

Blood samples were also collected at the beginning and end to measure gene expression and levels of inflammation.

«It's unclear to me how a nerve impulse could activate gene expression in a general way,» he says.

The transition actually shifts metabolic related gene expression, increasing fat oxidation pathways and decreasing fat storage pathways.

The research revealed fascinating physical similarities, and differences, in the patterns of gene expression across disorders including autism and schizophrenia.

Exposure to parental stress in early childhood has been shown to impact gene expression even years later in adolescence.

The resulting enzyme can increase gene expression without permanently changing the DNA.

Identifying gene expression patterns in relation to the compound could facilitate the selection of the most appropriate patient cohorts for clinical development.

Studies in certain geographic regions show different gene expressions depending on ethnic society.

To understand immune suppression in mice with genetically distinct pregnancies, the researchers examined gene expression patterns in immune cells during infection.

Genetic variants affecting gene expression show both shared and specific immune cell type effects.

New research shows that patients with psychiatric disorders like autism, schizophrenia and bipolar disorder have similar gene expressions in the brain.

From this data, a relative gene expression profile for each sample is made.

It is an important factor for the correct regulation of gene expression within all these groups of organisms.

The Core provides equipment and services to determine gene expression patterns in mouse and human tissues.

In the study, fragments of the virus that were not infectious were used to study viral gene expression.

But the technologies for spatial gene expression measurements are feasible to perform for individual labs that wants to study their tissue of on a genomic level.

We successfully established sequencing - based protocols to quantify gene expression of thousands of single cells.

Do think these folks had a clue about gene expression?

We feel that this is the only way to ultimately understand the regulatory mechanisms governing gene expression.

Highly coordinated gene expression networks ultimately produce all traits.

They next analyzed long gene expression in mice of different ages.

Another provocative observation from the new study was that transient gene expression events during brain development set up broad distinctions in neural fate between cells in different areas in the cerebral cortex.

The researchers also studied one of the risk factors in more detail and found a new regulatory signal that leads to increased gene expression in bone cancer cells from humans.

The researchers showed that this technique was successful in monitoring gene expression in a brain tumor in mice.