Not exact matches
Michael Skinner's claim that chemicals can cause
changes to
gene expression that persist
across multiple generations of animals has stirred excitement — and outrage.
We predicted a link between
gene expression evolution
across species and the degree of sexual selection, but this is the first statistical evidence for it and shows how powerful sexual selection can be in leading to major
changes in how a
gene is expressed.»
The most significant
changes occurred in a
gene called RbAp48, whose
expression declined steadily with aging
across the study subjects.
To work out the genetic basis, Duke University postdoctoral associate Bob Fitak and biology professor Sönke Johnsen and colleagues investigated
changes in
gene expression that take place
across the rainbow trout genome when the animal's magnetic sense is disrupted.
The bags» locations in the genome are similar
across cell types, although the bags» contents and roles can
change from transcription factors (blue OSN oval) and enhancers (red box) that promote the
gene (green)
expression (left diagram) or to repressors (right diagram) that inhbit
gene expression (gray box).
RNA - seq technology offers a rapid and scalable approach to characterize how
gene expression changes in response to experimental manipulations, and is applicable
across a wide range of taxa.
They focused their search on
expression levels of two sets of
genes, those that remained largely unchanged
across all four species, suggesting that there was little room — or need — for improvement, and those that
changed most dramatically, usually in the human lineage — an indication of powerful incentives to adapt to a
changing environment.